hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13977.1
Complex Portal: CPX-11581
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LIG4 | DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) | 5 | UniProt NCBI |
| APTX | Aprataxin (EC 3.6.1.71) (EC 3.6.1.72) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000012 | 0.0210690324038 | 1.0 | LIG4 APTX | single strand break repair |
| CORUM:213 | 0.0249718442457 | 0.5 | LIG4 | DNA ligase IV-XRCC1 complex |
| KEGG:03450 | 0.0261247873322 | 0.5 | LIG4 | Non-homologous end-joining |
| CORUM:206 | 0.0499419797295 | 0.5 | LIG4 | DNA ligase IV-XRCC4 complex |
| CORUM:344 | 0.0499419797295 | 0.5 | LIG4 | DNA ligase IV-XRCC4 complex |
| CORUM:345 | 0.0499419797295 | 0.5 | LIG4 | DNA ligase IV-XRCC4 complex |
| CORUM:348 | 0.0499419797295 | 0.5 | LIG4 | DNA ligase IV-XRCC4 complex |
| CORUM:352 | 0.0499419797295 | 0.5 | LIG4 | DNA ligase IV-XRCC4 complex |
| CORUM:354 | 0.0499419797295 | 0.5 | LIG4 | DNA ligase IV-XRCC4 complex |
| CORUM:359 | 0.0499419797295 | 0.5 | LIG4 | DNA ligase IV-XRCC4-XLF complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LIG4 | APTX | 0.89 | 0.082 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes