hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_13987.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BIRC7 | Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)] | 5 | UniProt NCBI |
| XIAP | E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP) | 5 | UniProt NCBI |
| OSTM1 | Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit) | 5 | UniProt NCBI |
| MORN3 | MORN repeat-containing protein 3 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04215 | 0.00101582950709 | 0.5 | BIRC7 XIAP | Apoptosis - multiple species |
| WP:WP1772 | 0.00761604886135 | 0.5 | BIRC7 XIAP | Apoptosis modulation and signaling |
| KEGG:05222 | 0.00909742323246 | 0.5 | BIRC7 XIAP | Small cell lung cancer |
| KEGG:05145 | 0.0101879335017 | 0.5 | BIRC7 XIAP | Toxoplasmosis |
| KEGG:04120 | 0.0224124539322 | 0.5 | BIRC7 XIAP | Ubiquitin mediated proteolysis |
| CORUM:6292 | 0.049938562206 | 0.25 | XIAP | HAX-1-XIAP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| OSTM1 | BIRC7 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MORN3 | XIAP | 0.975 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| OSTM1 | XIAP | 0.931 | 0.10641025641 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| XIAP | BIRC7 | 0.877 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes