hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_13994.1
Complex Portal: CPX-21011
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLEKHJ1 | Pleckstrin homology domain-containing family J member 1 (PH domain-containing family J member 1) (Guanine nucleotide-releasing protein x) | 3 | UniProt   NCBI |
| PHETA1 | Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1) | 5 | UniProt   NCBI |
| INPP5B | Type II inositol 1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36) (75 kDa inositol polyphosphate-5-phosphatase) (Phosphoinositide 5-phosphatase) (5PTase) | 5 | UniProt   NCBI |
| DENND4B | DENN domain-containing protein 4B | 4 | UniProt   NCBI |
| PHETA2 | Sesquipedalian-2 (Ses2) (27 kDa inositol polyphosphate phosphatase interacting protein B) (IPIP27B) (PH domain-containing endocytic trafficking adaptor 2) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   GO:0001881 | 0.00573353417253 | 0.6 | PLEKHJ1 PHETA2 PHETA1 | receptor recycling |
|   GO:0043112 | 0.0224016609185 | 0.6 | PLEKHJ1 PHETA2 PHETA1 | receptor metabolic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  INPP5B |  PHETA2 | 1.0 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  PLEKHJ1 |  PHETA1 | 1.0 |            |
mutually_exclusive (Q6ICB4)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  PLEKHJ1 |  PHETA2 | 1.0 |            |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  PHETA1 |  INPP5B | 0.999 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  PHETA1 |  PHETA2 | 0.998 |            |
structurally_consistent (dimer)        
|
bioplex3_WMM     bioplex3_HCT116     WMM_only     |
|  PLEKHJ1 |  INPP5B | 0.987 | 0.1           |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
|  PLEKHJ1 |  DENND4B | 0.981 | 0.076           |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  PHETA1 |  DENND4B | 0.113 |            |          | bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| PLEKHJ1 | huMAP3_03486.1 huMAP3_13994.1 |
| PHETA1 | huMAP3_03486.1 huMAP3_13994.1 |
| INPP5B | huMAP3_03486.1 huMAP3_13994.1 |
| DENND4B | huMAP3_03486.1 huMAP3_13994.1 |
| PHETA2 | huMAP3_03486.1 huMAP3_13994.1 |