hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14008.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AFF3 | AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4) | 5 | UniProt NCBI |
| TRMT10A | tRNA methyltransferase 10 homolog A (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 2) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10A) | 5 | UniProt NCBI |
| SYT2 | Synaptotagmin-2 (Synaptotagmin II) (SytII) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005943 | 0.00348901893966 | 0.666666666667 | AFF3 SYT2 | Respiratory arrest |
| HP:0001321 | 0.00973016767814 | 1.0 | TRMT10A AFF3 SYT2 | Cerebellar hypoplasia |
| HP:0001620 | 0.0103578783075 | 0.666666666667 | TRMT10A SYT2 | High pitched voice |
| HP:0007360 | 0.0149841228953 | 1.0 | TRMT10A AFF3 SYT2 | Aplasia/Hypoplasia of the cerebellum |
| HP:5200005 | 0.0173967419879 | 0.666666666667 | TRMT10A SYT2 | Abnormal pitch |
| HP:5200010 | 0.023094623718 | 0.666666666667 | TRMT10A SYT2 | Abnormal Intonation |
| HP:0031434 | 0.0304647837379 | 0.666666666667 | TRMT10A SYT2 | Abnormal prosody |
| HP:0011451 | 0.0313463863633 | 0.666666666667 | TRMT10A AFF3 | Primary microcephaly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TRMT10A | SYT2 | 0.971 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AFF3 | SYT2 | 0.954 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AFF3 | TRMT10A | 0.415 | bioplex3_WMM WMM_only |
Related Complexes