hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14013.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
GPR180 | Integral membrane protein GPR180 (Intimal thickness-related receptor) | 2 | UniProt   NCBI |
AGTR1 | Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor) | 5 | UniProt   NCBI |
TMEM11 | Transmembrane protein 11, mitochondrial (Protein PM1) (Protein PMI) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  WP:WP4799 | 0.0186595012434 | 0.5 | AGTR1 | Downregulation of ACE2 by SARS CoV 2 spike protein |
  WP:WP5076 | 0.0248784837172 | 0.5 | AGTR1 | Soluble ACE2 mediated cell entry of SARS CoV 2 |
  WP:WP5133 | 0.0310970405539 | 0.5 | AGTR1 | Non classical role of vitamin D |
  WP:WP4883 | 0.0373151717536 | 0.5 | AGTR1 | SARS CoV 2 and ACE2 receptor molecular mechanisms |
  KEGG:04614 | 0.0474849820587 | 0.5 | AGTR1 | Renin-angiotensin system |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 AGTR1 |  TMEM11 | 0.93 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 TMEM11 |  GPR180 | 0.892 | 0.078           | bioplex_WMM     bioplex3_WMM     WMM_only     boldt_WMM     |
 AGTR1 |  GPR180 | 0.041 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes
Genename | Complexes |
---|---|
GPR180 | huMAP3_14013.1 |
AGTR1 | huMAP3_11741.1 huMAP3_14013.1 |
TMEM11 | huMAP3_11741.1 huMAP3_14013.1 |