hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14061.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PLCD4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4) (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4) | 5 | UniProt NCBI |
| AFF3 | AF4/FMR2 family member 3 (Lymphoid nuclear protein related to AF4) (Protein LAF-4) | 5 | UniProt NCBI |
| MXD4 | Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4) | 3 | UniProt NCBI |
| WDR70 | WD repeat-containing protein 70 | 3 | UniProt NCBI |
| TRMT10A | tRNA methyltransferase 10 homolog A (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 2) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10A) | 5 | UniProt NCBI |
| SYT2 | Synaptotagmin-2 (Synaptotagmin II) (SytII) | 5 | UniProt NCBI |
| BRPF1 | Peregrin (Bromodomain and PHD finger-containing protein 1) (Protein Br140) | 5 | UniProt NCBI |
| MYC | Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0002714 | 0.046383752319 | 0.375 | AFF3 BRPF1 TRMT10A | Downturned corners of mouth |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TRMT10A | SYT2 | 0.971 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AFF3 | SYT2 | 0.954 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MXD4 | MYC | 0.946 | bioplex3_WMM WMM_only | |
| WDR70 | PLCD4 | 0.942 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SYT2 | WDR70 | 0.901 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MYC | BRPF1 | 0.899 | 0.472 | hein_WMM bioplex3_WMM hein () |
| BRPF1 | PLCD4 | 0.871 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| BRPF1 | SYT2 | 0.857 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MYC | SYT2 | 0.81 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| AFF3 | TRMT10A | 0.415 | bioplex3_WMM WMM_only | |
| BRPF1 | WDR70 | 0.37 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
| BRPF1 | AFF3 | 0.262 | bioplex_WMM bioplex3_WMM WMM_only | |
| MYC | TRMT10A | 0.21 | 0.342 | bioplex3_WMM WMM_only |
| MYC | WDR70 | 0.102 | 0.479333333333 | bioplex3_WMM WMM_only |
| TRMT10A | WDR70 | 0.095 | 0.08 | bioplex3_WMM WMM_only |
| BRPF1 | TRMT10A | 0.079 | 0.098 | bioplex3_WMM WMM_only |
| MYC | AFF3 | 0.078 | bioplex3_WMM WMM_only | |
| AFF3 | WDR70 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes