hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14067.1

Complex Portal: CPX-24430

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
CD99L2	CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99)	5	UniProt NCBI
GRM4	Metabotropic glutamate receptor 4 (mGluR4)	5	UniProt NCBI
GRM7	Metabotropic glutamate receptor 7 (mGluR7)	5	UniProt NCBI
RNF111	E3 ubiquitin-protein ligase Arkadia (EC 2.3.2.27) (RING finger protein 111) (hRNF111) (RING-type E3 ubiquitin transferase Arkadia)	5	UniProt NCBI

Showing 1 to 4 of 4 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP501	9.18788843787e-05	0.5	GRM4 GRM7	GPCRs class C metabotropic glutamate pheromone
REAC:R-HSA-420499	0.000931962666506	0.5	GRM4 GRM7	Class C/3 (Metabotropic glutamate/pheromone receptors)
GO:0007196	0.0028092043205	0.5	GRM4 GRM7	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
KEGG:04724	0.00806816574582	0.5	GRM4 GRM7	Glutamatergic synapse
GO:0001640	0.00842684400117	0.5	GRM4 GRM7	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0098988	0.00842684400117	0.5	GRM4 GRM7	G protein-coupled glutamate receptor activity
WP:WP5083	0.0154364529098	0.5	GRM4 GRM7	Neuroinflammation and glutamatergic signaling
KEGG:04072	0.0165563012031	0.5	GRM4 GRM7	Phospholipase D signaling pathway
CORUM:6357	0.0249718442456	0.25	GRM4	Glutamate receptor 4 complex, metabotropic
CORUM:6358	0.0249718442456	0.25	GRM7	Glutamate receptor 7 complex, metabotropic

Showing 1 to 10 of 16 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
RNF111	CD99L2	0.991			bioplex3_WMM bioplex3_HCT116 WMM_only
CD99L2	GRM4	0.988			bioplex3_HEK293 bioplex3_WMM WMM_only
GRM4	GRM7	0.986			bioplex3_HEK293 bioplex3_WMM WMM_only
CD99L2	GRM7	0.415			bioplex3_WMM WMM_only

Showing 1 to 4 of 4 entries

Related Complexes

Genename	Complexes
CD99L2	huMAP3_02210.1 huMAP3_07682.1 huMAP3_14067.1
GRM4	huMAP3_02210.1 huMAP3_07682.1 huMAP3_14067.1
GRM7	huMAP3_02210.1 huMAP3_14067.1
RNF111	huMAP3_01759.1 huMAP3_06386.1 huMAP3_08083.1 huMAP3_10162.1 huMAP3_14051.1 huMAP3_14067.1