hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14118.1

Complex Portal: CPX-11281

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
CS	Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase)	5	UniProt NCBI
FAM169A	Soluble lamin-associated protein of 75 kDa (SLAP75) (Protein FAM169A)	3	UniProt NCBI
FAM83G	Protein FAM83G (Protein associated with SMAD1)	5	UniProt NCBI
FBXO45	F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)	5	UniProt NCBI
FBXW7	F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)	5	UniProt NCBI
HDAC4	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	5	UniProt NCBI
HDAC7	Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a)	5	UniProt NCBI
HEY1	Hairy/enhancer-of-split related with YRPW motif protein 1 (Cardiovascular helix-loop-helix factor 2) (CHF-2) (Class B basic helix-loop-helix protein 31) (bHLHb31) (HES-related repressor protein 1) (Hairy and enhancer of split-related protein 1) (HESR-1) (Hairy-related transcription factor 1) (HRT-1) (hHRT1)	5	UniProt NCBI
IGFBP4	Insulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4)	5	UniProt NCBI
INHBE	Inhibin beta E chain (Activin beta-E chain)	4	UniProt NCBI

Showing 1 to 10 of 17 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-2122947	0.00303413678181	0.1875	HDAC4 HEY1 HDAC7	NOTCH1 Intracellular Domain Regulates Transcription
WP:WP4906	0.00338354586634	0.1875	MYCBP2 FBXO45 FBXW7	3q29 copy number variation syndrome
REAC:R-HSA-2894862	0.00495638650203	0.1875	HDAC4 HEY1 HDAC7	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
REAC:R-HSA-2644606	0.00495638650203	0.1875	HDAC4 HEY1 HDAC7	Constitutive Signaling by NOTCH1 PEST Domain Mutants
REAC:R-HSA-2894858	0.00495638650203	0.1875	HDAC4 HEY1 HDAC7	Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
REAC:R-HSA-2644602	0.00495638650203	0.1875	HDAC4 HEY1 HDAC7	Signaling by NOTCH1 PEST Domain Mutants in Cancer
REAC:R-HSA-2644603	0.00495638650203	0.1875	HDAC4 HEY1 HDAC7	Signaling by NOTCH1 in Cancer
REAC:R-HSA-1980143	0.00985760715853	0.1875	HDAC4 HEY1 HDAC7	Signaling by NOTCH1
WP:WP3996	0.0465207903625	0.125	HDAC4 HDAC7	Ethanol effects on histone modifications
CORUM:57	0.0497620750785	0.0625	HDAC4	HDAC4-ERK2 complex

Showing 1 to 10 of 11 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RASSF8	TP53BP2	1.0	0.148
PARD3	RASSF8	1.0	0.116
FBXO45	CS	0.997	0.154
INHBE	FBXO45	0.997
FBXO45	MYCBP2	0.995	0.1
CS	MYCBP2	0.993	0.108
FBXO45	SPRYD3	0.992	0.124
SPRYD3	MYCBP2	0.989	0.146
HEY1	CS	0.989
FAM83G	HDAC4	0.987	0.07

Showing 1 to 10 of 80 entries

Related Complexes

Genename	Complexes
FAM83G	huMAP3_00531.1 huMAP3_06269.1 huMAP3_09641.1 huMAP3_10898.1 huMAP3_14118.1
IGFBP4	huMAP3_02449.1 huMAP3_03816.1 huMAP3_07658.1 huMAP3_08066.1 huMAP3_09635.1 huMAP3_11188.1 huMAP3_11456.1 huMAP3_14118.1 huMAP3_14676.1
INHBE	huMAP3_00074.1 huMAP3_03816.1 huMAP3_09635.1 huMAP3_14118.1
IRS2	huMAP3_04537.1 huMAP3_07081.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_08092.1 huMAP3_09358.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1 huMAP3_11629.1 huMAP3_12185.1 huMAP3_12897.1 huMAP3_14118.1
SPRYD3	huMAP3_03816.1 huMAP3_09635.1 huMAP3_14118.1
HEY1	huMAP3_03816.1 huMAP3_09635.1 huMAP3_14118.1
PARD3	huMAP3_00531.1 huMAP3_03400.1 huMAP3_05806.1 huMAP3_06269.1 huMAP3_07838.1 huMAP3_09641.1 huMAP3_09726.1 huMAP3_09810.1 huMAP3_10212.1 huMAP3_10898.1 huMAP3_12987.1 huMAP3_14118.1
HDAC4	huMAP3_00531.1 huMAP3_04537.1 huMAP3_06269.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09641.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1 huMAP3_12897.1 huMAP3_14118.1
MYCBP2	huMAP3_04604.1 huMAP3_09635.1 huMAP3_11973.1 huMAP3_14118.1
FBXO45	huMAP3_03816.1 huMAP3_09635.1 huMAP3_14118.1
TP53BP2	huMAP3_01036.1 huMAP3_06304.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_10148.1 huMAP3_14118.1 huMAP3_14504.1
RASSF8	huMAP3_00531.1 huMAP3_01036.1 huMAP3_06269.1 huMAP3_09354.1 huMAP3_09633.1 huMAP3_09641.1 huMAP3_10148.1 huMAP3_10898.1 huMAP3_12886.1 huMAP3_14118.1
CS	huMAP3_03816.1 huMAP3_09635.1 huMAP3_14118.1
HDAC7	huMAP3_00531.1 huMAP3_06269.1 huMAP3_09641.1 huMAP3_10898.1 huMAP3_14118.1
PRR36	huMAP3_12702.1 huMAP3_13744.1 huMAP3_14118.1
FAM169A	huMAP3_14118.1
FBXW7	huMAP3_12702.1 huMAP3_14118.1