hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14129.1
Complex Portal: CPX-23774
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TSC22D4 | TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) | 5 | UniProt NCBI |
| WNK3 | Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3) | 5 | UniProt NCBI |
| NRG2 | Pro-neuregulin-2, membrane-bound isoform (Pro-NRG2) [Cleaved into: Neuregulin-2 (NRG-2) (Divergent of neuregulin-1) (DON-1) (Neural- and thymus-derived activator for ERBB kinases) (NTAK)] | 5 | UniProt NCBI |
| NRBP1 | Nuclear receptor-binding protein | 5 | UniProt NCBI |
| NRBP2 | Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16) | 4 | UniProt NCBI |
| SH2B3 | SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) | 5 | UniProt NCBI |
| TSC22D1 | TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein) | 5 | UniProt NCBI |
| C1QL3 | Complement C1q-like protein 3 (C1q and tumor necrosis factor-related protein 13) (C1q/TNF-related protein 13) | 4 | UniProt NCBI |
| TSC22D2 | TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4) | 4 | UniProt NCBI |
| TSC22D3 | TSC22 domain family protein 3 (DSIP-immunoreactive peptide) (Protein DIP) (hDIP) (Delta sleep-inducing peptide immunoreactor) (Glucocorticoid-induced leucine zipper protein) (GILZ) (TSC-22-like protein) (TSC-22-related protein) (TSC-22R) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TSC22D4 | NRBP1 | 1.0 | 0.2 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| TSC22D4 | TSC22D2 | 1.0 | 0.06 |
mutually_exclusive (Q99576)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TSC22D3 | NRBP1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | ||
| TSC22D4 | TSC22D1 | 1.0 | 0.072 |
mutually_exclusive (Q99576)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TSC22D2 | NRBP1 | 1.0 | 0.21 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TSC22D2 | TSC22D3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D1 | TSC22D3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D4 | TSC22D3 | 0.999 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D4 | NRBP2 | 0.999 | 0.034 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TSC22D1 | NRBP1 | 0.999 | 0.132 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NRBP2 | NRBP1 | 0.996 | 0.096 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TSC22D4 | SH2B3 | 0.993 | 0.11 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NRBP2 | TSC22D3 | 0.982 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NRBP2 | TSC22D1 | 0.962 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| TSC22D1 | TSC22D2 | 0.962 | 0.228 |
mutually_exclusive (Q99576)
|
bioplex_WMM bioplex3_WMM WMM_only |
| NRBP2 | TSC22D2 | 0.951 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only | |
| SH2B3 | TSC22D2 | 0.904 | 0.062 | bioplex3_WMM WMM_only | |
| TSC22D3 | C1QL3 | 0.897 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TSC22D2 | C1QL3 | 0.887 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| WNK3 | TSC22D4 | 0.873 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NRBP1 | NRG2 | 0.867 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SH2B3 | NRBP1 | 0.848 | 0.074 | bioplex3_WMM WMM_only | |
| NRBP1 | C1QL3 | 0.837 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TSC22D2 | NRG2 | 0.821 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| TSC22D3 | NRG2 | 0.733 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SH2B3 | TSC22D3 | 0.715 | bioplex3_WMM WMM_only | ||
| NRBP2 | SH2B3 | 0.698 | 0.07 | bioplex3_WMM WMM_only | |
| SH2B3 | TSC22D1 | 0.676 | 0.12 | bioplex3_WMM WMM_only | |
| WNK3 | TSC22D1 | 0.353 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only | |
| WNK3 | TSC22D3 | 0.227 | bioplex_WMM bioplex3_WMM WMM_only | ||
| WNK3 | NRBP1 | 0.216 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only | |
| WNK3 | NRBP2 | 0.215 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| WNK3 | TSC22D2 | 0.215 | 0.074 | bioplex_WMM bioplex3_WMM WMM_only | |
| WNK3 | SH2B3 | 0.214 | 0.144 | bioplex3_WMM WMM_only |
Related Complexes