hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14138.1

Complex Portal: CPX-24843

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
TSPAN33	Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane)	5	UniProt NCBI
MECOM	Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1)	5	UniProt NCBI
MYL1	Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) (MLC1F/MLC3F) (Myosin light chain alkali 1/2) (Myosin light chain A1/A2)	5	UniProt NCBI
MYOZ1	Myozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ)	5	UniProt NCBI
MYH4	Myosin-4 (Myosin heavy chain 2b) (MyHC-2b) (Myosin heavy chain 4) (Myosin heavy chain IIb) (MyHC-IIb) (Myosin heavy chain, skeletal muscle, fetal)	5	UniProt NCBI
MYBPC1	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform)	5	UniProt NCBI
MYH13	Myosin-13 (Myosin heavy chain 13) (Myosin heavy chain, skeletal muscle, extraocular) (MyHC-EO) (Myosin heavy chain, skeletal muscle, laryngeal) (MyHC-IIL) (Superfast myosin)	5	UniProt NCBI
LATS1	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)	5	UniProt NCBI
MYH1	Myosin-1 (Myosin heavy chain 1) (Myosin heavy chain 2x) (MyHC-2x) (Myosin heavy chain IIx/d) (MyHC-IIx/d) (Myosin heavy chain, skeletal muscle, adult 1)	5	UniProt NCBI
CKM	Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK)	5	UniProt NCBI
MYOM2	Myomesin-2 (165 kDa connectin-associated protein) (165 kDa titin-associated protein) (M-protein) (Myomesin family member 2)	5	UniProt NCBI
TLE3	Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)	5	UniProt NCBI
ACTN2	Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)	5	UniProt NCBI
MYH6	Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)	5	UniProt NCBI
MYH3	Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE)	5	UniProt NCBI
NEB	Nebulin	5	UniProt NCBI
ABTB2	Ankyrin repeat and BTB/POZ domain-containing protein 2	3	UniProt NCBI
MYL11	Myosin regulatory light chain 11 (Fast skeletal myosin light chain 2) (MLC2B) (Myosin light chain 11) (Myosin regulatory light chain 2, skeletal muscle isoform)	5	UniProt NCBI
MYH7	Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)	5	UniProt NCBI
LDB3	LIM domain-binding protein 3 (Protein cypher) (Z-band alternatively spliced PDZ-motif protein)	5	UniProt NCBI
ACTN3	Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein)	5	UniProt NCBI
MYH2	Myosin-2 (Myosin heavy chain 2) (Myosin heavy chain 2a) (MyHC-2a) (Myosin heavy chain IIa) (MyHC-IIa) (Myosin heavy chain, skeletal muscle, adult 2)	5	UniProt NCBI
MYBPC2	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform)	4	UniProt NCBI
TTN	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)	5	UniProt NCBI
PYGM	Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)	5	UniProt NCBI
TNNT3	Troponin T, fast skeletal muscle (TnTf) (Beta-TnTF) (Fast skeletal muscle troponin T) (fTnT)	5	UniProt NCBI
HIF1A	Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)	5	UniProt NCBI
RSPH6A	Radial spoke head protein 6 homolog A (Radial spoke head-like protein 1)	3	UniProt NCBI
MYH8	Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal)	5	UniProt NCBI
MYOM1	Myomesin-1 (190 kDa connectin-associated protein) (190 kDa titin-associated protein) (Myomesin family member 1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0043292	1.85517119751e-18	0.583333333333	MYOZ1 MYH2 NEB MYH4 MYH13 TNNT3 ACTN2 LDB3 MYBPC1 TTN MYOM1 ACTN3 MYL1 MYL11	contractile fiber
WP:WP383	1.38163802283e-16	0.375	TNNT3 NEB MYBPC2 TTN ACTN2 MYBPC1 MYOM1 ACTN3 MYL1	Striated muscle contraction pathway
GO:0008307	1.44201129788e-16	0.416666666667	MYL11 MYOM2 TTN MYBPC2 ACTN2 MYBPC1 MYOM1 ACTN3 MYL1 NEB	structural constituent of muscle
GO:0030016	1.63928089424e-14	0.5	MYOZ1 NEB MYH4 TTN TNNT3 ACTN2 LDB3 MYBPC1 MYOM1 ACTN3 MYL1 MYH2	myofibril
REAC:R-HSA-390522	5.79052488898e-14	0.333333333333	TNNT3 NEB MYBPC2 TTN ACTN2 MYBPC1 ACTN3 MYL1	Striated Muscle Contraction
GO:0030017	4.11559415008e-13	0.458333333333	MYOZ1 NEB TNNT3 TTN ACTN2 LDB3 MYH4 MYOM1 ACTN3 MYL1 MYH2	sarcomere
REAC:R-HSA-397014	3.40648358531e-10	0.375	TNNT3 MYL11 MYBPC2 TTN ACTN2 MYBPC1 ACTN3 MYL1 NEB	Muscle contraction
GO:0099512	8.01886041544e-10	0.583333333333	MYOZ1 MYH2 NEB MYH4 MYH13 TNNT3 ACTN2 LDB3 MYBPC1 TTN MYOM1 ACTN3 MYL1 MYL11	supramolecular fiber
GO:0099081	9.52645361608e-10	0.583333333333	MYOZ1 MYH2 NEB MYH4 MYH13 TNNT3 ACTN2 LDB3 MYBPC1 TTN MYOM1 ACTN3 MYL1 MYL11	supramolecular polymer
GO:0015629	7.23352001795e-09	0.5	MYOZ1 MYH2 NEB TNNT3 MYH13 ACTN2 LDB3 MYH4 TTN ACTN3 MYL1 MYL11	actin cytoskeleton
GO:0030029	5.74954815449e-08	0.541666666667	MYOZ1 MYH2 NEB MYH4 TTN TNNT3 ACTN2 LDB3 MYOM2 ACTN3 LATS1 MYL1 MYL11	actin filament-based process
GO:0003012	7.05368422197e-08	0.416666666667	MYOZ1 MYL11 MYH4 MYH13 TNNT3 MYOM2 TTN ACTN3 MYL1 MYH2	muscle system process
GO:0099080	3.66398067699e-07	0.583333333333	MYOZ1 MYH2 NEB MYH4 MYH13 TNNT3 ACTN2 LDB3 MYBPC1 TTN MYOM1 ACTN3 MYL1 MYL11	supramolecular complex
GO:0003779	3.80933236919e-07	0.416666666667	MYOZ1 NEB TNNT3 MYH13 ACTN2 LDB3 MYH4 TTN ACTN3 MYH2	actin binding
GO:0006936	7.69426993427e-07	0.375	TNNT3 MYL11 MYOM2 MYH13 MYH4 TTN ACTN3 MYL1 MYH2	muscle contraction
GO:0005859	1.13691957783e-06	0.208333333333	MYL11 MYH4 MYH2 MYL1 MYH13	muscle myosin complex
HPA:0440343	2.06230706087e-06	0.458333333333	CKM MYH2 MECOM MYOZ1 MYBPC2 ACTN2 MYBPC1 MYOM2 TNNT3 MYL1 NEB	skeletal muscle; myocytes[High]
GO:0030239	3.37507529641e-06	0.25	MYOZ1 NEB TNNT3 TTN ACTN2 MYOM2	myofibril assembly
GO:0055002	3.89019895357e-06	0.25	MYOZ1 NEB TNNT3 TTN ACTN2 MYOM2	striated muscle cell development
GO:0055001	4.20967788482e-06	0.291666666667	MYOZ1 NEB TNNT3 TTN ACTN2 MYOM2 ACTN3	muscle cell development
KEGG:04814	1.17613829761e-05	0.25	TNNT3 MYL11 MYH13 MYH4 MYL1 MYH2	Motor proteins
GO:0016460	1.26292585988e-05	0.208333333333	MYL11 MYH4 MYH2 MYL1 MYH13	myosin II complex
HPA:0440342	1.54617801715e-05	0.75	MYL11 MYOZ1 MYH2 MECOM LDB3 MYBPC1 TTN MYBPC2 CKM TNNT3 ACTN2 MYH4 MYOM2 TSPAN33 MYOM1 LATS1 MYL1 NEB	skeletal muscle; myocytes[>=Medium]
GO:0045214	1.59354506072e-05	0.208333333333	MYOZ1 TTN ACTN2 TNNT3 MYOM2	sarcomere organization
HP:0003803	4.24530892724e-05	0.208333333333	TTN MYH2 NEB MYL1 ACTN2	Type 1 muscle fiber predominance
GO:0030018	5.10189950298e-05	0.25	MYOZ1 NEB TTN ACTN2 LDB3 ACTN3	Z disc
HP:0003701	5.33686211996e-05	0.291666666667	MYH2 TTN LDB3 ACTN2 MYBPC1 MYL1 NEB	Proximal muscle weakness
GO:0061061	5.34891236299e-05	0.375	MYOZ1 MYL11 TNNT3 TTN ACTN2 LDB3 MYOM2 ACTN3 NEB	muscle structure development
GO:0010927	6.09871781631e-05	0.25	MYOZ1 NEB TNNT3 TTN ACTN2 MYOM2	cellular component assembly involved in morphogenesis
GO:0016459	7.48466908255e-05	0.208333333333	MYL11 MYH4 MYH2 MYL1 MYH13	myosin complex
GO:0031674	9.3165454753e-05	0.25	MYOZ1 NEB TTN ACTN2 LDB3 ACTN3	I band
HP:0033684	0.000136913881407	0.208333333333	TTN MYH2 NEB MYL1 ACTN2	Abnormal muscle fiber-type distribution
GO:0005198	0.000151989923474	0.416666666667	MYL11 MYOM2 TTN MYBPC2 ACTN2 MYBPC1 MYOM1 ACTN3 MYL1 NEB	structural molecule activity
GO:0008092	0.000230262492868	0.458333333333	MYOZ1 NEB MYH4 MYH13 TNNT3 ACTN2 LDB3 MYBPC1 TTN ACTN3 MYH2	cytoskeletal protein binding
GO:0033275	0.000276827676899	0.166666666667	MYH4 MYH2 MYL1 MYL11	actin-myosin filament sliding
GO:0051015	0.000357939134385	0.291666666667	MYH2 MYH13 ACTN2 MYH4 TTN ACTN3 NEB	actin filament binding
HP:0003327	0.000407748222839	0.166666666667	MYBPC1 TTN MYL1 NEB	Axial muscle weakness
HP:0003557	0.000489056358775	0.208333333333	TTN MYH2 NEB MYL1 ACTN2	Increased variability in muscle fiber diameter
GO:0005856	0.000611746527943	0.583333333333	MYOZ1 MYH2 NEB TNNT3 MYH13 ACTN2 LDB3 MYH4 ACTN3 LATS1 TTN RSPH6A MYL1 MYL11	cytoskeleton
GO:0042692	0.000621945195681	0.291666666667	MYOZ1 NEB TNNT3 TTN ACTN2 MYOM2 ACTN3	muscle cell differentiation
HP:0012084	0.00063378770657	0.208333333333	TTN MYH2 NEB MYL1 ACTN2	Abnormality of skeletal muscle fiber size
GO:0032982	0.000656031490424	0.166666666667	MYH4 MYOM1 MYH2 MYH13	myosin filament
HP:0002460	0.000760455182429	0.25	MYH2 TTN ACTN2 LDB3 MYBPC1 NEB	Distal muscle weakness
HP:0003324	0.0013365421958	0.208333333333	TTN MYH2 MYL1 LDB3 NEB	Generalized muscle weakness
GO:0051146	0.00177929651928	0.25	MYOZ1 NEB TNNT3 TTN ACTN2 MYOM2	striated muscle cell differentiation
HP:0004303	0.00203734484986	0.25	MYH2 TTN LDB3 ACTN2 MYL1 NEB	Abnormal muscle fiber morphology
HP:0003555	0.00224053295878	0.125	TTN NEB LDB3	Muscle fiber splitting
HP:0003457	0.00225030275029	0.25	NEB TTN LDB3 ACTN2 MYBPC1 MYL1	EMG abnormality
HPA:0440000	0.00272137420945	0.791666666667	MYL11 MYOZ1 MYH2 MECOM LDB3 MYBPC1 TTN MYBPC2 CKM TNNT3 ACTN2 MYH4 MYOM2 TSPAN33 MYOM1 LATS1 ABTB2 MYL1 NEB	skeletal muscle
HPA:0440341	0.00272137420945	0.791666666667	MYL11 MYOZ1 MYH2 MECOM LDB3 MYBPC1 TTN MYBPC2 CKM TNNT3 ACTN2 MYH4 MYOM2 TSPAN33 MYOM1 LATS1 ABTB2 MYL1 NEB	skeletal muscle; myocytes[>=Low]
HP:0030059	0.00331342048059	0.0833333333333	TTN NEB	Mitochondrial depletion
HP:0009077	0.00400521012882	0.125	TTN NEB LDB3	Weakness of long finger extensor muscles
GO:0030036	0.00413989657902	0.375	MYOZ1 NEB TNNT3 TTN ACTN2 LDB3 MYOM2 ACTN3 LATS1	actin cytoskeleton organization
GO:0031032	0.00499348711555	0.25	MYOZ1 NEB TNNT3 TTN ACTN2 MYOM2	actomyosin structure organization
HP:0003198	0.00592642546759	0.25	MYH2 TTN ACTN2 LDB3 MYBPC1 NEB	Myopathy
WP:WP5402	0.00676515571942	0.125	RSPH6A ACTN2 LDB3	10q22q23 copy number variation
HP:0000467	0.0080613707095	0.166666666667	TTN MYH2 MYL1 NEB	Neck muscle weakness
HP:0000218	0.0101225291318	0.333333333333	TNNT3 NEB MYL11 TTN ACTN2 MYBPC1 MYL1 MYH2	High palate
HP:0003272	0.0109189073562	0.291666666667	TNNT3 MYL11 TTN MECOM MYBPC1 MYL1 NEB	Abnormal hip bone morphology
HP:0002792	0.0112043178905	0.125	TTN ACTN2 NEB	Reduced vital capacity
HP:0003691	0.0132827639448	0.166666666667	MYBPC1 TTN NEB MYH2	Scapular winging
HP:0005750	0.0141651060075	0.208333333333	MYL11 MYBPC1 TTN MYL1 NEB	Lower-limb joint contracture
HP:0010557	0.0159073169909	0.125	MYBPC1 MECOM TNNT3	Overlapping fingers
HP:0000174	0.0182562016765	0.375	TNNT3 MYH2 MYL11 TTN MECOM ACTN2 MYBPC1 MYL1 NEB	Abnormal palate morphology
HP:0000160	0.020620829629	0.208333333333	MYBPC1 TTN NEB TNNT3 MYL11	Narrow mouth
HP:0001376	0.0212994849922	0.25	TNNT3 MYL11 TTN MYBPC1 MYL1 MECOM	Limitation of joint mobility
HP:0002644	0.0226403651664	0.291666666667	TNNT3 MYL11 TTN MECOM MYBPC1 MYL1 NEB	Abnormal pelvic girdle bone morphology
HP:0001181	0.0306783794231	0.166666666667	MYBPC1 TNNT3 NEB MYL11	Adducted thumb
HP:0003458	0.0318465039788	0.166666666667	MYBPC1 TTN NEB LDB3	EMG: myopathic abnormalities
GO:0003008	0.0324401225811	0.416666666667	MYOZ1 MYL11 MYH4 MYH13 TNNT3 MYOM2 TTN ACTN3 MYL1 MYH2	system process
HP:0031237	0.0330345446309	0.0833333333333	TTN ACTN2	Internally nucleated skeletal muscle fibers
HP:0003805	0.0405236307779	0.125	TTN ACTN2 NEB	Rimmed vacuoles
HP:0003121	0.0410395138018	0.25	TNNT3 MYL11 TTN MYBPC1 MYL1 NEB	Limb joint contracture
GO:0030049	0.0423869429414	0.125	MYH4 MYL1 MYH2	muscle filament sliding
HP:0001446	0.0428417498611	0.208333333333	MYBPC1 MYH2 NEB TTN LDB3	Abnormality of the musculature of the upper limbs
HP:0008366	0.0469572325324	0.166666666667	MYBPC1 TTN NEB MYL11	Foot joint contracture
HP:0006685	0.0495020942397	0.0833333333333	ACTN2 LDB3	Endocardial fibrosis
CORUM:1987	0.0497620750785	0.0416666666667	MYOM1	MYOM1 homodimer complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
LATS1	MYOZ1	0.997
MYOM2	TSPAN33	0.997		structurally_consistent (dimer)
MYOM1	TSPAN33	0.997
TSPAN33	NEB	0.997
MYBPC1	TSPAN33	0.996
MYH4	MYH3	0.996
MYL1	MYH1	0.995
TSPAN33	MYBPC2	0.993		structurally_consistent (dimer)
TSPAN33	LDB3	0.993
MYH6	HIF1A	0.993
TTN	TSPAN33	0.992
MYH7	MYH4	0.992
MYH6	MYH3	0.991
LATS1	MYH6	0.991
MYH7	MYH3	0.991
LATS1	MYOM2	0.991
MYH8	MYH4	0.99
MYH13	RSPH6A	0.99
LATS1	TNNT3	0.99
LATS1	TTN	0.989
MYH4	MYL1	0.989		structurally_consistent (dimer)
LDB3	RSPH6A	0.986
MYL11	TSPAN33	0.986
TLE3	MYH3	0.986
HIF1A	MYH2	0.986
TLE3	MYH2	0.986	0.038
LATS1	MYBPC1	0.985
MYH13	TSPAN33	0.985
RSPH6A	MYH2	0.985
TNNT3	TSPAN33	0.985
LATS1	LDB3	0.984
MYL11	RSPH6A	0.984
HIF1A	MYH3	0.984
LATS1	MYOM1	0.984	0.074
TLE3	MYOM1	0.983
MYH1	MYH2	0.983
LATS1	MYH1	0.982
MYH1	TSPAN33	0.982
TNNT3	RSPH6A	0.982
MYH8	RSPH6A	0.981
TSPAN33	MYH2	0.981
LATS1	MYBPC2	0.981
MYH4	MYH1	0.98
MYL1	TSPAN33	0.98
MYH4	TSPAN33	0.98
MYH7	TSPAN33	0.98
LATS1	MYH2	0.98	0.13
LATS1	MYH13	0.979
TTN	RSPH6A	0.979
MYL1	MYH3	0.979
LATS1	NEB	0.979	0.182
MYH8	TSPAN33	0.978
LATS1	MYH3	0.978
PYGM	TSPAN33	0.978		structurally_consistent (dimer)
TLE3	MYH1	0.976
TLE3	MYH8	0.976
ACTN2	MYH2	0.976	0.244
LATS1	MYL11	0.976
LATS1	MYH8	0.975
LATS1	MYL1	0.975
MYH1	ACTN2	0.975
TLE3	MYBPC2	0.974
LATS1	MYH4	0.974
MYH1	HIF1A	0.974
MYH13	MYH8	0.973
MYH8	ACTN2	0.973
MYH7	MYL1	0.972
TLE3	MYH4	0.972
LATS1	PYGM	0.972	0.13
MYH1	RSPH6A	0.972
MYOM2	RSPH6A	0.971
MYBPC1	RSPH6A	0.971
RSPH6A	MYBPC2	0.971
MYH7	ACTN3	0.969	0.054
CKM	TSPAN33	0.969		structurally_consistent (dimer)
MYH1	MYH3	0.969
ACTN3	TSPAN33	0.967
ABTB2	MYH6	0.967
MYH8	MYH2	0.967
TLE3	MYL1	0.966
MYH8	MYH7	0.965
MYL1	HIF1A	0.965
MYH4	RSPH6A	0.961
NEB	RSPH6A	0.961
MYH4	HIF1A	0.961
MYH6	ACTN2	0.959
MYH4	MYH2	0.959
PYGM	MYH2	0.957	0.134
MYH7	MYH2	0.956	0.274
MYH1	PYGM	0.954
TLE3	MYH7	0.952	0.036
MYH7	RSPH6A	0.947
LATS1	MYH7	0.945	0.086
MYH4	ACTN2	0.944
ABTB2	LDB3	0.944
MYH7	MYH1	0.942
MYH8	MYH1	0.941
MYH7	ACTN2	0.941	0.226
MYOM1	ABTB2	0.939	0.032
MECOM	MYBPC2	0.937
ACTN2	ACTN3	0.937	0.13
MECOM	MYOM2	0.937
ABTB2	MYBPC2	0.931
MYH3	MYH2	0.928
CKM	RSPH6A	0.928
PYGM	RSPH6A	0.925
MYH2	MYBPC2	0.925
ABTB2	MYH2	0.924	0.032
MYL11	MYBPC2	0.924
TTN	MYBPC2	0.922
MYL11	TTN	0.918
TNNT3	ABTB2	0.915
ACTN2	TSPAN33	0.915
MYL11	MECOM	0.912
ABTB2	MYH3	0.911
CKM	LATS1	0.91
MYL11	MYH2	0.909
TTN	MYH2	0.907
ACTN2	MYH3	0.905
MYOZ1	TNNT3	0.904
MYOZ1	MYH3	0.904
MYOZ1	MYH2	0.904
ABTB2	NEB	0.903	0.068
MYL1	MYH2	0.903
MYOZ1	MYH6	0.902
MYOZ1	MYOM1	0.902
MYOZ1	MYBPC2	0.902
MYOZ1	MYH13	0.902
MYOZ1	TTN	0.902
MYOZ1	MYOM2	0.902
MYOZ1	MYL11	0.902
MYOZ1	LDB3	0.902
MYOZ1	MYBPC1	0.902
MYOZ1	NEB	0.902
NEB	MYH2	0.902	0.176
MYL1	MYL11	0.901
MYH8	MYH3	0.901
MYL1	TTN	0.9
MYH8	TTN	0.899
MYH1	MYBPC2	0.898
MYH8	MYL11	0.898
MYH1	MYL11	0.898
MYL1	MYBPC2	0.898
MYH4	MYBPC2	0.898
MYH8	MYBPC2	0.898
MYH7	MYBPC2	0.898
LATS1	ACTN3	0.897	0.064
MYH1	MYH6	0.896
MYH4	MYL11	0.896
MYH13	MYH3	0.892
MYBPC1	MYH6	0.892
TTN	NEB	0.892
MYH7	MYL11	0.89
MYH1	TTN	0.89
MYH4	TTN	0.887
MYOZ1	MYH1	0.883
TNNT3	MECOM	0.881
MYOZ1	PYGM	0.881
MYL1	NEB	0.88
MYH1	NEB	0.88
MYH8	PYGM	0.871
TNNT3	MYL11	0.87
MECOM	MYH2	0.869
MYH1	ABTB2	0.869
MYH8	ABTB2	0.869
PYGM	TTN	0.868
PYGM	MYL11	0.865
PYGM	MYBPC2	0.865
CKM	MYL11	0.865
MYH4	NEB	0.864
MYH8	NEB	0.864
CKM	MYBPC2	0.864		mutually_exclusive (Q86UF1)
CKM	NEB	0.864
TNNT3	MYH2	0.864
MYH4	MYH6	0.863
MYL1	PYGM	0.86
CKM	MYH4	0.859
TNNT3	TTN	0.856
MYL11	NEB	0.856
TNNT3	NEB	0.856
TNNT3	MYBPC2	0.856
MYL11	MYOM1	0.856
TTN	MYOM1	0.855
MYH7	MYOM1	0.854	0.112
MYL1	MECOM	0.852
CKM	TNNT3	0.849
NEB	MYBPC2	0.848
ACTN3	RSPH6A	0.848
MYOM1	MYBPC2	0.847
TTN	ACTN2	0.846
MYH7	MECOM	0.846
MYOM1	MYH2	0.844	0.058
PYGM	NEB	0.843	0.178
MYH1	TNNT3	0.84
MYH4	TNNT3	0.84
MYH8	TNNT3	0.84
TNNT3	ACTN3	0.834
MYH8	MYOM1	0.834
MYH1	MYOM1	0.834
MYH4	MYOM1	0.834
MYL1	MYOM1	0.834
MYH8	MECOM	0.83
MYH4	ABTB2	0.83
CKM	ACTN3	0.829
MYH1	MECOM	0.828
MYH4	MECOM	0.826
CKM	MYH8	0.826
MYH7	TTN	0.825
PYGM	TNNT3	0.824
MYH6	MYH2	0.823
MYL11	ACTN2	0.822
TTN	ACTN3	0.813
MYOZ1	ACTN2	0.81
MYH4	PYGM	0.808
CKM	MECOM	0.806
ACTN2	MYBPC2	0.802
ACTN2	NEB	0.802	0.242
MYL1	ACTN3	0.8
ACTN2	LDB3	0.799
TLE3	TTN	0.799
MYL11	ACTN3	0.798
CKM	TTN	0.798
MYH7	MYOM2	0.797
MYH7	NEB	0.797	0.15
MYH6	MYBPC2	0.796
MYH6	NEB	0.796
TTN	MYH6	0.796
MYH6	LDB3	0.796
MYH13	MYH6	0.796
MYOM1	MYH6	0.796
MYL11	MYH6	0.796
TNNT3	MYBPC1	0.792
PYGM	MYBPC1	0.792
CKM	LDB3	0.791
MYH8	MYOM2	0.79
MYOM2	ACTN3	0.79
MYH4	MYOM2	0.79
CKM	MYOM2	0.79		mutually_exclusive (Q86UF1)
ACTN3	NEB	0.79	0.078
MYH4	LDB3	0.79
ACTN3	MYBPC2	0.79
MYL1	MYOM2	0.79
ACTN3	MYH2	0.79	0.02
MYH8	MYL1	0.789
MYOM1	ACTN2	0.787	0.134
MYL11	MYBPC1	0.785
MYH13	MYBPC1	0.785
MYBPC1	LDB3	0.785
MYOM1	LDB3	0.785
MYH13	MYL1	0.784		structurally_consistent (dimer)
MYH7	LDB3	0.784
ACTN3	LDB3	0.784
MYH4	MYBPC1	0.783
MYL1	MYBPC1	0.783
MYH13	MYH2	0.783
MYH13	TTN	0.783
CKM	MYOM1	0.783
MYH7	MYBPC1	0.783
CKM	MYBPC1	0.783
MYH1	MYBPC1	0.783
MYBPC1	ACTN3	0.783
MYH8	MYBPC1	0.783
PYGM	MYH6	0.781
MYH13	MYL11	0.777
MYH13	NEB	0.777
MYOM2	LDB3	0.777
MYH13	LDB3	0.777
MYH13	MYBPC2	0.777
MYH13	MYOM2	0.777
TNNT3	MYOM1	0.777
MYBPC1	MYH2	0.777
MYH1	MYOM2	0.775
MYL1	LDB3	0.773
CKM	MYL1	0.772
TNNT3	MYH6	0.772
CKM	MYH7	0.771
MYOM1	NEB	0.765	0.09
TTN	MYBPC1	0.765
CKM	MYH2	0.764
PYGM	ACTN3	0.759	0.0464166666667
PYGM	LDB3	0.758
PYGM	MYOM2	0.758
MYH13	PYGM	0.758
MYBPC1	MYOM2	0.757
MYBPC1	MYBPC2	0.757
MYBPC1	NEB	0.757
MYH7	TNNT3	0.757
TNNT3	MYOM2	0.756
MYH1	LDB3	0.756
MYL11	MYOM2	0.756
TNNT3	LDB3	0.756
LDB3	MYBPC2	0.756
LDB3	MYH2	0.756
MYOM2	MYH2	0.756
MYH8	LDB3	0.756
LDB3	NEB	0.756
MYL11	LDB3	0.756
TTN	LDB3	0.756
MYH13	TNNT3	0.756
CKM	MYH1	0.756
TLE3	MYL11	0.755
MYL1	TNNT3	0.752
MYOZ1	MYH4	0.751
MYOM2	NEB	0.744
TTN	MYOM2	0.744
MYOM2	MYBPC2	0.744
MECOM	NEB	0.74
MYH4	ACTN3	0.733
MYH3	MYBPC2	0.732
MYOM1	MYH3	0.732
MYH6	MYOM2	0.73
LATS1	ACTN2	0.719	0.132
MYL11	MYH3	0.714
TTN	MYH3	0.712
TNNT3	ACTN2	0.706
MYH7	PYGM	0.688	0.092
TTN	MECOM	0.687
ACTN2	MYOM2	0.683
MYH3	ACTN3	0.679
MYL1	MYH6	0.675
MYL1	RSPH6A	0.671
TTN	ABTB2	0.669
MYH13	MYH4	0.667		mutually_exclusive (P05976)
CKM	MYH13	0.667
MYH13	MYH7	0.667
MYH13	ACTN3	0.667
MYH8	ACTN3	0.667
MYH13	ACTN2	0.662
MYBPC1	ACTN2	0.662
CKM	PYGM	0.655		mutually_exclusive (Q86UF1)
MYH13	MYH1	0.647
MYH13	MYOM1	0.633
MYOM1	ACTN3	0.633	0.002
MYOZ1	MYH8	0.626
MYH1	ACTN3	0.615
MYOM1	MYOM2	0.596
MYL1	ACTN2	0.566
MYBPC1	MYOM1	0.564
PYGM	ACTN2	0.55	0.228
PYGM	MYOM1	0.54	0.046
MYH3	NEB	0.537
MECOM	ACTN3	0.534
CKM	ABTB2	0.52
MYH8	MYH6	0.512
CKM	MYH6	0.504
PYGM	MYH3	0.499
MYH6	ACTN3	0.49
MYH7	MYH6	0.479
MYH3	LDB3	0.477
TNNT3	MYH3	0.477
CKM	ACTN2	0.461
MYOZ1	MYL1	0.455
MYL1	ABTB2	0.436
MYL11	ABTB2	0.425
MYOZ1	ACTN3	0.418
CKM	MYOZ1	0.418
MYBPC1	MYH3	0.41
PYGM	HIF1A	0.4
MYOZ1	MYH7	0.388
MYOM2	MYH3	0.364
CKM	MYH3	0.265
PYGM	ABTB2	0.263	0.052
ABTB2	ACTN2	0.2	0.094
PYGM	MECOM	0.181
TLE3	MECOM	0.147
TLE3	PYGM	0.039	0.024
ACTN2	RSPH6A	0.019
ACTN2	HIF1A	0.013
MECOM	ACTN2	0.011
TLE3	ACTN2	0.008	0.084
TLE3	NEB	0.006	0.076
TLE3	HIF1A	0.006
TLE3	LATS1	0.005	0.100909090909

Related Complexes

Genename	Complexes
TSPAN33	huMAP3_07933.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
MECOM	huMAP3_03205.1 huMAP3_05273.1 huMAP3_06451.1 huMAP3_07714.1 huMAP3_10093.1 huMAP3_10331.1 huMAP3_14138.1
MYL1	huMAP3_01597.1 huMAP3_08441.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_13982.1 huMAP3_14138.1
MYOZ1	huMAP3_00581.1 huMAP3_03011.1 huMAP3_07504.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10383.1 huMAP3_10799.1 huMAP3_14138.1
MYH4	huMAP3_01597.1 huMAP3_08441.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
MYBPC1	huMAP3_03011.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10383.1 huMAP3_10799.1 huMAP3_12943.1 huMAP3_14138.1
MYH13	huMAP3_00683.1 huMAP3_03725.1 huMAP3_05020.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
LATS1	huMAP3_00581.1 huMAP3_03011.1 huMAP3_07504.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10383.1 huMAP3_10799.1 huMAP3_14138.1
MYH1	huMAP3_02460.1 huMAP3_08441.1 huMAP3_09455.1 huMAP3_10799.1 huMAP3_14138.1
CKM	huMAP3_00497.1 huMAP3_09546.1 huMAP3_12854.1 huMAP3_14138.1
MYOM2	huMAP3_03713.1 huMAP3_05027.1 huMAP3_06073.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10732.1 huMAP3_10799.1 huMAP3_11143.1 huMAP3_11407.1 huMAP3_11751.1 huMAP3_12644.1 huMAP3_14138.1
TLE3	huMAP3_00022.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_11616.1 huMAP3_14138.1 huMAP3_14261.1
ACTN2	huMAP3_03382.1 huMAP3_05719.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_11050.1 huMAP3_14138.1
MYH6	huMAP3_03382.1 huMAP3_09076.1 huMAP3_09913.1 huMAP3_10799.1 huMAP3_14138.1
MYH3	huMAP3_06057.1 huMAP3_08441.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
NEB	huMAP3_07933.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
ABTB2	huMAP3_03230.1 huMAP3_09913.1 huMAP3_14138.1
MYL11	huMAP3_02931.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_09693.1 huMAP3_10799.1 huMAP3_14138.1
MYH7	huMAP3_01597.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
LDB3	huMAP3_07933.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
ACTN3	huMAP3_06664.1 huMAP3_08324.1 huMAP3_10949.1 huMAP3_11403.1 huMAP3_12864.1 huMAP3_14138.1
MYH2	huMAP3_08759.1 huMAP3_09455.1 huMAP3_10799.1 huMAP3_14138.1
MYBPC2	huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
TTN	huMAP3_03011.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10383.1 huMAP3_10799.1 huMAP3_14138.1
PYGM	huMAP3_02460.1 huMAP3_07933.1 huMAP3_08093.1 huMAP3_09076.1 huMAP3_09760.1 huMAP3_10799.1 huMAP3_11993.1 huMAP3_12186.1 huMAP3_14138.1
TNNT3	huMAP3_02931.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_09693.1 huMAP3_10799.1 huMAP3_14138.1
HIF1A	huMAP3_06057.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14050.1 huMAP3_14138.1 huMAP3_14853.1
RSPH6A	huMAP3_07933.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_12943.1 huMAP3_14138.1
MYH8	huMAP3_00683.1 huMAP3_08759.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1
MYOM1	huMAP3_03011.1 huMAP3_07933.1 huMAP3_09076.1 huMAP3_10383.1 huMAP3_10799.1 huMAP3_14138.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_14138.1

Complex Portal: CPX-24843