hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14178.1

Complex Portal: CPX-18685

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
HSPA9	Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)	5	UniProt NCBI
LONRF1	LON peptidase N-terminal domain and RING finger protein 1 (RING finger protein 191)	5	UniProt NCBI
KIF15	Kinesin-like protein KIF15 (Kinesin-like protein 2) (hKLP2) (Kinesin-like protein 7) (Serologically defined breast cancer antigen NY-BR-62)	5	UniProt NCBI
ISCU	Iron-sulfur cluster assembly enzyme ISCU (NifU-like N-terminal domain-containing protein) (NifU-like protein)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP5152	0.000232143427839	0.5	HSPA9 ISCU	Iron sulfur cluster biogenesis
HP:0001924	0.0165423111708	0.5	HSPA9 ISCU	Sideroblastic anemia
CORUM:7124	0.049938562206	0.25	HSPA9	HSPA9-GRPEL1 complex
CORUM:7125	0.049938562206	0.25	HSPA9	HSPA9-GRPEL2 complex
REAC:R-HSA-9694301	0.0499436884912	0.25	ISCU	Maturation of replicase proteins

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ISCU	HSPA9	0.975	0.272		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction boldt_WMM
LONRF1	ISCU	0.956			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
KIF15	HSPA9	0.885	0.077		hein_WMM bioplex_WMM bioplex3_WMM WMM_only boldt_WMM
LONRF1	HSPA9	0.019			bioplex3_HEK293 bioplex ()

Related Complexes

Genename	Complexes
HSPA9	huMAP3_07445.1 huMAP3_11030.1 huMAP3_14178.1
LONRF1	huMAP3_02575.1 huMAP3_12331.1 huMAP3_14178.1
KIF15	huMAP3_04725.1 huMAP3_06422.1 huMAP3_06916.1 huMAP3_07678.1 huMAP3_14178.1 huMAP3_14950.1
ISCU	huMAP3_02575.1 huMAP3_14178.1 huMAP3_14759.1