hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14181.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FOXE3 | Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead-related transcription factor 8) (FREAC-8) | 5 | UniProt NCBI |
| PARM1 | Prostate androgen-regulated mucin-like protein 1 (PARM-1) | 5 | UniProt NCBI |
| OSM | Oncostatin-M (OSM) | 5 | UniProt NCBI |
| IL6ST | Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130) | 5 | UniProt NCBI |
| C5orf22 | UPF0489 protein C5orf22 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3229 | 0.049938562206 | 0.25 | IL6ST | CDK9-IL6ST complex |
| CORUM:5579 | 0.049938562206 | 0.25 | IL6ST | CNTF-CNTFR-gp130-LIFR complex |
| CORUM:5582 | 0.049938562206 | 0.25 | IL6ST | LIFR-LIF-gp130 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| C5orf22 | OSM | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| OSM | IL6ST | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| IL6ST | PARM1 | 0.945 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| C5orf22 | IL6ST | 0.903 | 0.022 | bioplex_WMM bioplex3_WMM WMM_only |
| C5orf22 | FOXE3 | 0.815 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes