hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14201.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GIGYF1 | GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1) | 5 | UniProt NCBI |
| LSM12 | Protein LSM12 | 5 | UniProt NCBI |
| ATXN2 | Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein) | 5 | UniProt NCBI |
| MCRIP2 | MAPK regulated corepressor interacting protein 2 (Protein FAM195A) | 4 | UniProt NCBI |
| TRIM11 | E3 ubiquitin-protein ligase TRIM11 (EC 2.3.2.27) (Protein BIA1) (RING finger protein 92) (Tripartite motif-containing protein 11) | 5 | UniProt NCBI |
| DDX6 | Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK) | 5 | UniProt NCBI |
| ATXN2L | Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein) | 5 | UniProt NCBI |
| DMRTB1 | Doublesex- and mab-3-related transcription factor B1 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0010494 | 0.00245296942189 | 0.5 | MCRIP2 ATXN2L ATXN2 DDX6 | cytoplasmic stress granule |
| GO:0034063 | 0.0139126682532 | 0.375 | DDX6 ATXN2 ATXN2L | stress granule assembly |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LSM12 | ATXN2L | 1.0 | 0.514 | youn () bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| MCRIP2 | LSM12 | 1.0 | 0.146 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| MCRIP2 | ATXN2L | 0.999 | 0.09 | youn () bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| LSM12 | DDX6 | 0.999 | 0.114 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| ATXN2L | DDX6 | 0.998 | 0.334 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM |
| MCRIP2 | DDX6 | 0.998 | 0.122 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| ATXN2 | MCRIP2 | 0.998 | 0.092 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| DMRTB1 | TRIM11 | 0.997 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | |
| ATXN2L | TRIM11 | 0.996 | 0.194 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ATXN2 | LSM12 | 0.996 | 0.216 | youn () bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction |
| ATXN2 | DDX6 | 0.986 | 0.31 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM treiber_WMM |
| MCRIP2 | TRIM11 | 0.957 | 0.118 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| LSM12 | TRIM11 | 0.944 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ATXN2 | ATXN2L | 0.92 | 0.54 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| DDX6 | TRIM11 | 0.823 | 0.222 | bioplex_WMM bioplex3_WMM fraction |
| ATXN2 | TRIM11 | 0.159 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only |
| ATXN2 | DMRTB1 | 0.041 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATXN2L | DMRTB1 | 0.016 | bioplex3_HCT116 WMM_only | |
| DDX6 | DMRTB1 | 0.004 | bioplex3_HCT116 WMM_only |
Related Complexes