hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14214.1
Complex Portal: CPX-19111
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PPM1A | Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA) | 5 | UniProt NCBI |
| CERKL | Ceramide kinase-like protein | 5 | UniProt NCBI |
| PPM1B | Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta) | 5 | UniProt NCBI |
| RASL11B | Ras-like protein family member 11B (EC 3.6.5.2) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0006498 | 0.0168521501606 | 0.5 | PPM1A PPM1B | N-terminal protein lipidation |
| GO:0006499 | 0.0168521501606 | 0.5 | PPM1A PPM1B | N-terminal protein myristoylation |
| GO:0018377 | 0.0168521501606 | 0.5 | PPM1A PPM1B | protein myristoylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CERKL | PPM1A | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| PPM1B | PPM1A | 0.997 | 0.234 |
mutually_exclusive (Q9BPW5)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM |
| PPM1B | CERKL | 0.948 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PPM1A | RASL11B | 0.915 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PPM1B | RASL11B | 0.285 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PPM1A | huMAP3_09227.1 huMAP3_10009.1 huMAP3_14214.1 |
| CERKL | huMAP3_06408.1 huMAP3_11246.1 huMAP3_14214.1 |
| PPM1B | huMAP3_00643.1 huMAP3_07361.1 huMAP3_09738.1 huMAP3_13627.1 huMAP3_14214.1 |
| RASL11B | huMAP3_14214.1 |