hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14264.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UTP4 | U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component) | 5 | UniProt NCBI |
| UTP15 | U3 small nucleolar RNA-associated protein 15 homolog | 5 | UniProt NCBI |
| ZCCHC8 | Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8) | 5 | UniProt NCBI |
| WDR75 | WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) | 5 | UniProt NCBI |
| MPHOSPH6 | M-phase phosphoprotein 6 | 5 | UniProt NCBI |
| EXOSC2 | Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) | 5 | UniProt NCBI |
| EXOSC1 | Exosome complex component CSL4 (Exosome component 1) | 5 | UniProt NCBI |
| DIS3L | DIS3-like exonuclease 1 (EC 3.1.13.1) | 5 | UniProt NCBI |
| EXOSC6 | Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11) | 5 | UniProt NCBI |
| EXOSC8 | Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9) | 5 | UniProt NCBI |
| EXOSC9 | Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) | 5 | UniProt NCBI |
| EXOSC3 | Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10) | 5 | UniProt NCBI |
| EXOSC7 | Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8) | 5 | UniProt NCBI |
| MTREX | Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) | 5 | UniProt NCBI |
| NOL11 | Nucleolar protein 11 | 4 | UniProt NCBI |
| EXOSC4 | Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A) | 5 | UniProt NCBI |
| WDR43 | WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog) | 5 | UniProt NCBI |
| EXOSC5 | Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B) | 5 | UniProt NCBI |
| C1D | Nuclear nucleic acid-binding protein C1D (hC1D) | 5 | UniProt NCBI |
| HBS1L | HBS1-like protein (EC 3.6.5.-) (ERFS) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7443 | 4.53309265109e-31 | 0.55 | EXOSC7 EXOSC5 EXOSC3 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC6 MPHOSPH6 EXOSC8 DIS3L | Exosome |
| GO:1905354 | 1.99119955278e-29 | 0.65 | EXOSC7 EXOSC5 EXOSC3 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC6 MPHOSPH6 C1D EXOSC8 MTREX DIS3L | exoribonuclease complex |
| GO:0000178 | 1.99119955278e-29 | 0.65 | EXOSC7 EXOSC5 EXOSC3 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC6 MPHOSPH6 C1D EXOSC8 MTREX DIS3L | exosome (RNase complex) |
| GO:0000176 | 5.79619008508e-29 | 0.6 | EXOSC7 EXOSC5 EXOSC3 EXOSC1 EXOSC2 EXOSC4 EXOSC9 MPHOSPH6 C1D EXOSC8 MTREX EXOSC6 | nuclear exosome (RNase complex) |
| REAC:R-HSA-6791226 | 5.47880087882e-28 | 0.85 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 C1D EXOSC1 MTREX UTP4 NOL11 EXOSC6 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 1.43015734931e-27 | 0.85 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 C1D EXOSC1 MTREX UTP4 NOL11 EXOSC6 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 3.54576597217e-27 | 0.85 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 C1D EXOSC1 MTREX UTP4 NOL11 EXOSC6 | rRNA processing |
| GO:0016072 | 5.22447116763e-25 | 0.85 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 C1D DIS3L MTREX UTP4 NOL11 EXOSC6 | rRNA metabolic process |
| CORUM:788 | 7.32494661877e-25 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Exosome |
| KEGG:03018 | 1.75853838513e-24 | 0.65 | EXOSC7 EXOSC5 EXOSC3 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC6 MPHOSPH6 C1D EXOSC8 MTREX DIS3L | RNA degradation |
| REAC:R-HSA-429958 | 3.7476271078e-24 | 0.5 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 HBS1L EXOSC1 | mRNA decay by 3' to 5' exoribonuclease |
| CORUM:789 | 4.02598980755e-24 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Exosome |
| GO:0000177 | 6.03367964356e-22 | 0.5 | DIS3L EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC8 EXOSC6 | cytoplasmic exosome (RNase complex) |
| GO:0101019 | 1.00351768677e-21 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | nucleolar exosome (RNase complex) |
| GO:0006364 | 2.61784741778e-21 | 0.75 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 EXOSC2 C1D EXOSC8 WDR43 UTP4 NOL11 MTREX | rRNA processing |
| REAC:R-HSA-450513 | 7.10162997295e-21 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA |
| GO:0034470 | 1.06935625571e-20 | 0.85 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 C1D ZCCHC8 MTREX UTP4 NOL11 EXOSC6 | ncRNA processing |
| REAC:R-HSA-450604 | 1.50807310154e-20 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | KSRP (KHSRP) binds and destabilizes mRNA |
| REAC:R-HSA-450385 | 1.50807310154e-20 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA |
| GO:0034660 | 4.50860120105e-20 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX UTP4 NOL11 DIS3L | ncRNA metabolic process |
| REAC:R-HSA-8953854 | 5.05492119982e-20 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 C1D EXOSC1 MTREX HBS1L UTP4 NOL11 EXOSC6 | Metabolism of RNA |
| GO:0034475 | 1.22236042457e-19 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | U4 snRNA 3'-end processing |
| GO:0006396 | 3.67900150382e-19 | 0.95 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX UTP4 NOL11 EXOSC1 | RNA processing |
| GO:0034661 | 8.83714817446e-19 | 0.55 | DIS3L EXOSC7 EXOSC5 MTREX EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC8 ZCCHC8 EXOSC6 | ncRNA catabolic process |
| GO:0042254 | 1.88984621138e-18 | 0.75 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 EXOSC2 C1D EXOSC8 WDR43 UTP4 NOL11 MTREX | ribosome biogenesis |
| REAC:R-HSA-380994 | 1.92651748521e-18 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | ATF4 activates genes in response to endoplasmic reticulum stress |
| GO:0016075 | 4.85270251669e-18 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 DIS3L | rRNA catabolic process |
| REAC:R-HSA-381042 | 1.23880724777e-17 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | PERK regulates gene expression |
| REAC:R-HSA-429914 | 1.33590897411e-17 | 0.5 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 HBS1L EXOSC1 | Deadenylation-dependent mRNA decay |
| GO:0034427 | 2.0124792221e-17 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' |
| GO:0071027 | 3.65469234502e-16 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | nuclear RNA surveillance |
| GO:0016073 | 1.16551352636e-15 | 0.5 | EXOSC7 EXOSC5 MTREX EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 ZCCHC8 | snRNA metabolic process |
| GO:0022613 | 1.40877969717e-15 | 0.75 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 EXOSC2 C1D EXOSC8 WDR43 UTP4 NOL11 MTREX | ribonucleoprotein complex biogenesis |
| GO:0071025 | 1.56400921869e-15 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | RNA surveillance |
| GO:0000460 | 3.81034927307e-15 | 0.45 | EXOSC7 MTREX EXOSC3 EXOSC4 EXOSC9 EXOSC2 MPHOSPH6 EXOSC8 C1D | maturation of 5.8S rRNA |
| GO:0000291 | 1.52636441201e-14 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | nuclear-transcribed mRNA catabolic process, exonucleolytic |
| GO:0006401 | 2.46303377341e-14 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | RNA catabolic process |
| GO:0034472 | 2.4638639181e-14 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | snRNA 3'-end processing |
| GO:0016180 | 1.88470592708e-13 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | snRNA processing |
| REAC:R-HSA-450531 | 1.94962082749e-13 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Regulation of mRNA stability by proteins that bind AU-rich elements |
| REAC:R-HSA-381119 | 2.18208920598e-13 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Unfolded Protein Response (UPR) |
| GO:0005730 | 8.53956156471e-13 | 0.8 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 EXOSC2 EXOSC8 C1D EXOSC1 WDR43 UTP4 NOL11 EXOSC6 | nucleolus |
| GO:0034655 | 9.66241287081e-12 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | nucleobase-containing compound catabolic process |
| GO:0046700 | 2.37647737084e-11 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | heterocycle catabolic process |
| GO:0044270 | 2.45126485935e-11 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | cellular nitrogen compound catabolic process |
| GO:0019439 | 2.85878675543e-11 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | aromatic compound catabolic process |
| GO:0071028 | 3.00006608103e-11 | 0.3 | EXOSC7 EXOSC9 EXOSC4 EXOSC8 EXOSC5 EXOSC6 | nuclear mRNA surveillance |
| GO:1901361 | 4.61955513563e-11 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | organic cyclic compound catabolic process |
| GO:0043928 | 2.44544521275e-10 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | exonucleolytic catabolism of deadenylated mRNA |
| GO:0000956 | 5.14442348697e-10 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 HBS1L EXOSC8 | nuclear-transcribed mRNA catabolic process |
| GO:0000175 | 9.0371004676e-10 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | 3'-5'-RNA exonuclease activity |
| GO:0016896 | 2.06060827465e-09 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | RNA exonuclease activity, producing 5'-phosphomonoesters |
| GO:0004532 | 2.49575905902e-09 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | RNA exonuclease activity |
| GO:0071029 | 2.92667108476e-09 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | nuclear ncRNA surveillance |
| GO:0071035 | 2.92667108476e-09 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | nuclear polyadenylation-dependent rRNA catabolic process |
| GO:0071038 | 2.92667108476e-09 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | nuclear polyadenylation-dependent tRNA catabolic process |
| GO:0071046 | 2.92667108476e-09 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | nuclear polyadenylation-dependent ncRNA catabolic process |
| GO:0016070 | 3.80687962813e-09 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | RNA metabolic process |
| GO:0031123 | 5.04055511564e-09 | 0.4 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 EXOSC8 | RNA 3'-end processing |
| GO:0140513 | 7.54794878689e-09 | 0.75 | EXOSC7 EXOSC5 EXOSC3 MTREX MPHOSPH6 EXOSC4 EXOSC9 EXOSC2 EXOSC8 C1D EXOSC1 ZCCHC8 UTP4 NOL11 EXOSC6 | nuclear protein-containing complex |
| GO:0003723 | 7.7526715191e-09 | 0.8 | EXOSC7 WDR75 C1D EXOSC3 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 EXOSC1 MTREX UTP4 NOL11 ZCCHC8 | RNA binding |
| GO:0043633 | 7.79777844544e-09 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | polyadenylation-dependent RNA catabolic process |
| GO:0043634 | 7.79777844544e-09 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | polyadenylation-dependent ncRNA catabolic process |
| GO:0071051 | 7.79777844544e-09 | 0.25 | EXOSC4 EXOSC2 EXOSC5 EXOSC6 EXOSC3 | polyadenylation-dependent snoRNA 3'-end processing |
| GO:0106354 | 7.79777844544e-09 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | tRNA surveillance |
| GO:0000467 | 1.75299888387e-08 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0008408 | 1.77424057892e-08 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | 3'-5' exonuclease activity |
| GO:0016796 | 2.04263842536e-08 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0031125 | 3.50299770166e-08 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | rRNA 3'-end processing |
| GO:0090304 | 4.45181652697e-08 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | nucleic acid metabolic process |
| GO:0031126 | 1.09905870225e-07 | 0.25 | EXOSC4 EXOSC2 EXOSC5 EXOSC6 EXOSC3 | sno(s)RNA 3'-end processing |
| GO:0006402 | 1.18569099698e-07 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 HBS1L EXOSC8 | mRNA catabolic process |
| GO:0043144 | 1.7844419879e-07 | 0.25 | EXOSC4 EXOSC2 EXOSC5 EXOSC6 EXOSC3 | sno(s)RNA processing |
| GO:0004527 | 1.92334642348e-07 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | exonuclease activity |
| GO:0006139 | 3.67482666118e-07 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | nucleobase-containing compound metabolic process |
| GO:0016078 | 4.15657421171e-07 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | tRNA catabolic process |
| GO:0016074 | 4.15657421171e-07 | 0.25 | EXOSC4 EXOSC2 EXOSC5 EXOSC6 EXOSC3 | sno(s)RNA metabolic process |
| GO:0046483 | 6.58630997614e-07 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | heterocycle metabolic process |
| GO:0006725 | 7.00899535086e-07 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | cellular aromatic compound metabolic process |
| GO:0016071 | 1.29658456264e-06 | 0.55 | EXOSC7 EXOSC5 MTREX EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 HBS1L ZCCHC8 | mRNA metabolic process |
| GO:1901360 | 1.44354273853e-06 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | organic cyclic compound metabolic process |
| GO:0010467 | 1.56092634503e-06 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | gene expression |
| GO:0004540 | 2.35520764139e-06 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | RNA nuclease activity |
| GO:0009057 | 3.01291241048e-06 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | macromolecule catabolic process |
| GO:0034641 | 3.47647015828e-06 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | cellular nitrogen compound metabolic process |
| GO:0000466 | 3.62321209544e-06 | 0.25 | EXOSC2 EXOSC7 EXOSC3 EXOSC8 EXOSC9 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| REAC:R-HSA-6790901 | 4.14481232756e-06 | 0.25 | UTP4 WDR43 UTP15 NOL11 WDR75 | rRNA modification in the nucleus and cytosol |
| GO:0009059 | 8.06819866495e-06 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | macromolecule biosynthetic process |
| GO:0000288 | 8.41444425822e-06 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| GO:0032991 | 1.27773392589e-05 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | protein-containing complex |
| GO:0044248 | 1.34588359119e-05 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | cellular catabolic process |
| GO:1902494 | 1.86089100686e-05 | 0.7 | EXOSC7 EXOSC5 EXOSC3 MTREX EXOSC2 EXOSC4 EXOSC9 EXOSC6 MPHOSPH6 EXOSC8 C1D EXOSC1 ZCCHC8 DIS3L | catalytic complex |
| GO:0045006 | 2.66313661765e-05 | 0.2 | EXOSC3 EXOSC5 EXOSC6 EXOSC4 | DNA deamination |
| REAC:R-HSA-2262752 | 5.38614540045e-05 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Cellular responses to stress |
| GO:0004518 | 5.68217431812e-05 | 0.35 | EXOSC7 EXOSC3 EXOSC2 EXOSC9 EXOSC4 DIS3L EXOSC5 | nuclease activity |
| REAC:R-HSA-8953897 | 5.84793361804e-05 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC6 EXOSC2 EXOSC8 EXOSC1 | Cellular responses to stimuli |
| GO:0005654 | 6.55846462281e-05 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX UTP4 NOL11 EXOSC1 | nucleoplasm |
| GO:0061157 | 7.77897155309e-05 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | mRNA destabilization |
| HP:0004886 | 9.09957458529e-05 | 0.15 | EXOSC9 EXOSC8 EXOSC3 | Congenital laryngeal stridor |
| GO:0050779 | 9.52188127139e-05 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | RNA destabilization |
| GO:0061014 | 0.000101701712283 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | positive regulation of mRNA catabolic process |
| GO:0043232 | 0.000104482477937 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 EXOSC2 EXOSC8 EXOSC6 EXOSC1 WDR43 HBS1L UTP4 NOL11 DIS3L | intracellular non-membrane-bounded organelle |
| GO:0043228 | 0.000104482477937 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 EXOSC2 EXOSC8 EXOSC6 EXOSC1 WDR43 HBS1L UTP4 NOL11 DIS3L | non-membrane-bounded organelle |
| GO:0044249 | 0.000107135022537 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | cellular biosynthetic process |
| GO:0034473 | 0.000109576846827 | 0.15 | EXOSC9 EXOSC8 EXOSC7 | U1 snRNA 3'-end processing |
| GO:0034476 | 0.000109576846827 | 0.15 | EXOSC9 EXOSC8 EXOSC7 | U5 snRNA 3'-end processing |
| GO:1901576 | 0.000126076411928 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | organic substance biosynthetic process |
| GO:0009058 | 0.000142326407017 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | biosynthetic process |
| KEGG:03008 | 0.000156419332967 | 0.2 | UTP4 UTP15 WDR43 WDR75 | Ribosome biogenesis in eukaryotes |
| CORUM:7349 | 0.000194638873543 | 0.1 | ZCCHC8 MTREX | MTR4-RBM7-ZCCHC8 complex |
| GO:0031981 | 0.000201516485834 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX UTP4 NOL11 EXOSC1 | nuclear lumen |
| GO:0140098 | 0.000219724116163 | 0.4 | EXOSC7 MTREX EXOSC3 EXOSC4 EXOSC9 EXOSC2 DIS3L EXOSC5 | catalytic activity, acting on RNA |
| GO:1901575 | 0.000263304556569 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | organic substance catabolic process |
| GO:0003676 | 0.00028110733103 | 0.8 | EXOSC7 WDR75 C1D EXOSC3 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 EXOSC1 MTREX UTP4 NOL11 ZCCHC8 | nucleic acid binding |
| GO:1903313 | 0.00038845291997 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | positive regulation of mRNA metabolic process |
| GO:0071042 | 0.000437924933217 | 0.15 | EXOSC9 EXOSC8 EXOSC7 | nuclear polyadenylation-dependent mRNA catabolic process |
| GO:0071047 | 0.000437924933217 | 0.15 | EXOSC9 EXOSC8 EXOSC7 | polyadenylation-dependent mRNA catabolic process |
| GO:0097159 | 0.000482444976423 | 0.85 | EXOSC7 WDR75 C1D EXOSC3 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 EXOSC1 MTREX HBS1L UTP4 NOL11 ZCCHC8 | organic cyclic compound binding |
| GO:0044085 | 0.000616742136617 | 0.75 | EXOSC7 EXOSC5 EXOSC3 WDR75 MPHOSPH6 EXOSC4 EXOSC9 UTP15 EXOSC2 C1D EXOSC8 WDR43 UTP4 NOL11 MTREX | cellular component biogenesis |
| HP:0005348 | 0.000739680930563 | 0.15 | EXOSC9 EXOSC8 EXOSC3 | Inspiratory stridor |
| GO:0043488 | 0.0011534519082 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | regulation of mRNA stability |
| GO:0043487 | 0.00174850330588 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | regulation of RNA stability |
| GO:0061013 | 0.00204848440653 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | regulation of mRNA catabolic process |
| HP:0002398 | 0.00210122732653 | 0.15 | EXOSC9 EXOSC8 EXOSC3 | Degeneration of anterior horn cells |
| HP:0006802 | 0.00249303032448 | 0.15 | EXOSC9 EXOSC8 EXOSC3 | Abnormal anterior horn cell morphology |
| CORUM:822 | 0.00290284517391 | 0.1 | EXOSC2 EXOSC4 | mRNA decay complex (UPF1, UPF2, UPF3B, DCP2, XRN1, XRN2, EXOSC2, EXOSC4, EXOSC10, PARN) |
| GO:0009056 | 0.00390192977449 | 0.65 | EXOSC7 EXOSC5 EXOSC1 EXOSC3 EXOSC4 EXOSC9 MTREX EXOSC6 EXOSC2 EXOSC8 ZCCHC8 HBS1L DIS3L | catabolic process |
| HP:0012110 | 0.00405760883832 | 0.2 | EXOSC9 EXOSC3 EXOSC1 EXOSC8 | Hypoplasia of the pons |
| GO:0043170 | 0.00429302442438 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | macromolecule metabolic process |
| GO:0045943 | 0.00575876059091 | 0.2 | NOL11 UTP15 WDR43 WDR75 | positive regulation of transcription by RNA polymerase I |
| GO:0140640 | 0.00708895687729 | 0.4 | EXOSC7 MTREX EXOSC3 EXOSC4 EXOSC9 EXOSC2 DIS3L EXOSC5 | catalytic activity, acting on a nucleic acid |
| GO:0042274 | 0.00710011914424 | 0.25 | UTP4 WDR43 UTP15 NOL11 WDR75 | ribosomal small subunit biogenesis |
| GO:0031974 | 0.00823103225323 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX UTP4 NOL11 EXOSC1 | membrane-enclosed lumen |
| GO:0043233 | 0.00823103225323 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX UTP4 NOL11 EXOSC1 | organelle lumen |
| GO:0070013 | 0.00823103225323 | 0.9 | EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX UTP4 NOL11 EXOSC1 | intracellular organelle lumen |
| HP:0007361 | 0.0100966493633 | 0.2 | EXOSC9 EXOSC3 EXOSC1 EXOSC8 | Abnormal pons morphology |
| GO:0010629 | 0.0105738456627 | 0.45 | EXOSC7 EXOSC5 EXOSC3 EXOSC4 EXOSC9 EXOSC2 EXOSC6 HBS1L EXOSC8 | negative regulation of gene expression |
| HP:0001308 | 0.0114441733377 | 0.15 | EXOSC9 EXOSC8 EXOSC3 | Tongue fasciculations |
| GO:2000234 | 0.0130691170406 | 0.15 | WDR43 UTP15 WDR75 | positive regulation of rRNA processing |
| GO:0006807 | 0.013511035506 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | nitrogen compound metabolic process |
| GO:0006356 | 0.0167097438311 | 0.2 | NOL11 UTP15 WDR43 WDR75 | regulation of transcription by RNA polymerase I |
| WP:WP4352 | 0.0203073106199 | 0.2 | EXOSC4 EXOSC2 EXOSC7 EXOSC9 | Ciliary landscape |
| HP:0010307 | 0.024957439701 | 0.15 | EXOSC9 EXOSC8 EXOSC3 | Stridor |
| GO:0044237 | 0.0274985384047 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | cellular metabolic process |
| GO:1903311 | 0.0287316334241 | 0.3 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC5 EXOSC8 | regulation of mRNA metabolic process |
| GO:0044238 | 0.0335492388027 | 1.0 | DIS3L EXOSC7 EXOSC5 EXOSC3 WDR75 C1D MPHOSPH6 EXOSC4 EXOSC9 UTP15 WDR43 EXOSC2 EXOSC8 EXOSC6 ZCCHC8 MTREX HBS1L UTP4 NOL11 EXOSC1 | primary metabolic process |
| HPA:0090162 | 0.0351842512347 | 0.65 | EXOSC7 EXOSC3 MTREX MPHOSPH6 EXOSC4 EXOSC9 EXOSC2 EXOSC1 C1D HBS1L UTP4 NOL11 ZCCHC8 | cerebellum; Purkinje cells[>=Medium] |
| GO:0006304 | 0.0480708749151 | 0.2 | EXOSC3 EXOSC5 EXOSC6 EXOSC4 | DNA modification |
| GO:0051254 | 0.0486253924609 | 0.5 | EXOSC7 WDR75 EXOSC3 EXOSC9 UTP15 EXOSC2 EXOSC8 WDR43 NOL11 EXOSC5 | positive regulation of RNA metabolic process |
| HP:0030810 | 0.0490804565205 | 0.15 | EXOSC9 EXOSC8 EXOSC3 | Abnormal tongue physiology |
| CORUM:2004 | 0.0499436884912 | 0.05 | C1D | C1D homodimer protein |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| EXOSC6 | EXOSC2 | 1.0 | 0.946 |
| EXOSC5 | EXOSC2 | 1.0 | 0.972 |
| EXOSC1 | EXOSC2 | 1.0 | 0.944 |
| EXOSC1 | EXOSC4 | 1.0 | 0.842 |
| EXOSC7 | MPHOSPH6 | 1.0 | 0.208 |
| EXOSC4 | EXOSC6 | 1.0 | 0.764 |
| EXOSC1 | MPHOSPH6 | 1.0 | 0.416 |
| EXOSC4 | EXOSC2 | 1.0 | 0.97 |
| MPHOSPH6 | EXOSC5 | 1.0 | 0.236 |
| MPHOSPH6 | EXOSC2 | 1.0 | 0.166 |
| EXOSC4 | EXOSC5 | 1.0 | 0.966 |
| EXOSC8 | MPHOSPH6 | 1.0 | 0.136 |
| EXOSC2 | EXOSC9 | 1.0 | 0.992 |
| EXOSC3 | MPHOSPH6 | 1.0 | 0.246 |
| MPHOSPH6 | EXOSC6 | 1.0 | 0.322 |
| MPHOSPH6 | EXOSC9 | 1.0 | 0.132 |
| EXOSC1 | EXOSC9 | 1.0 | 0.978 |
| EXOSC3 | EXOSC7 | 1.0 | 0.982 |
| EXOSC2 | C1D | 1.0 | 0.356 |
| EXOSC4 | MPHOSPH6 | 1.0 | 0.426 |
| EXOSC6 | EXOSC5 | 1.0 | 0.634 |
| EXOSC3 | EXOSC6 | 1.0 | 0.946 |
| EXOSC8 | EXOSC2 | 1.0 | 0.902 |
| MTREX | C1D | 1.0 | 0.334 |
| EXOSC4 | C1D | 1.0 | 0.438 |
| EXOSC1 | C1D | 1.0 | 0.528 |
| EXOSC3 | EXOSC9 | 1.0 | 0.994 |
| EXOSC3 | EXOSC2 | 1.0 | 0.982 |
| EXOSC3 | EXOSC5 | 1.0 | 0.982 |
| EXOSC6 | C1D | 1.0 | 0.256 |
| EXOSC1 | EXOSC5 | 1.0 | 0.962 |
| EXOSC4 | EXOSC9 | 1.0 | 0.97 |
| EXOSC5 | EXOSC9 | 1.0 | 0.982 |
| EXOSC1 | EXOSC7 | 1.0 | 0.932 |
| C1D | EXOSC9 | 1.0 | 0.3 |
| EXOSC7 | EXOSC2 | 1.0 | 0.988 |
| MPHOSPH6 | C1D | 1.0 | 0.314 |
| EXOSC7 | EXOSC4 | 1.0 | 0.974 |
| MTREX | EXOSC2 | 1.0 | 0.81 |
| EXOSC5 | C1D | 1.0 | 0.366 |
| EXOSC7 | EXOSC5 | 1.0 | 0.95 |
| EXOSC1 | DIS3L | 1.0 | 0.136 |
| EXOSC3 | C1D | 1.0 | 0.546 |
| MTREX | MPHOSPH6 | 1.0 | 0.128 |
| DIS3L | EXOSC4 | 1.0 | 0.23 |
| EXOSC8 | EXOSC5 | 1.0 | 0.712 |
| EXOSC3 | EXOSC4 | 1.0 | 0.974 |
| EXOSC1 | EXOSC3 | 1.0 | 0.966 |
| EXOSC6 | EXOSC9 | 1.0 | 0.688 |
| UTP4 | UTP15 | 1.0 | 0.99 |
| ZCCHC8 | C1D | 1.0 | 0.13 |
| EXOSC1 | EXOSC8 | 1.0 | 0.884 |
| UTP4 | WDR75 | 1.0 | 0.93 |
| EXOSC1 | EXOSC6 | 1.0 | 0.928 |
| DIS3L | EXOSC2 | 1.0 | 0.132 |
| EXOSC7 | C1D | 1.0 | 0.501428571429 |
| DIS3L | EXOSC5 | 1.0 | 0.17 |
| EXOSC7 | EXOSC9 | 1.0 | 0.982 |
| EXOSC7 | DIS3L | 1.0 | 0.108 |
| EXOSC3 | DIS3L | 1.0 | 0.202 |
| UTP4 | WDR43 | 1.0 | 0.946 |
| UTP4 | NOL11 | 1.0 | 0.94 |
| EXOSC3 | HBS1L | 1.0 | 0.092 |
| EXOSC7 | EXOSC6 | 0.999 | 0.788 |
| EXOSC3 | MTREX | 0.999 | 0.746 |
| EXOSC8 | EXOSC4 | 0.999 | 0.778 |
| DIS3L | MPHOSPH6 | 0.999 | 0.09 |
| EXOSC3 | EXOSC8 | 0.999 | 0.856 |
| MTREX | EXOSC5 | 0.999 | 0.576 |
| EXOSC3 | ZCCHC8 | 0.999 | 0.192 |
| EXOSC7 | EXOSC8 | 0.999 | 0.944 |
| EXOSC4 | ZCCHC8 | 0.999 | 0.156 |
| EXOSC7 | MTREX | 0.999 | 0.79 |
| EXOSC1 | HBS1L | 0.999 | 0.084 |
| EXOSC8 | EXOSC9 | 0.999 | 0.934 |
| MTREX | EXOSC4 | 0.999 | 0.588 |
| DIS3L | C1D | 0.999 | 0.132 |
| EXOSC7 | HBS1L | 0.999 | 0.1 |
| EXOSC8 | EXOSC6 | 0.999 | 0.706 |
| EXOSC7 | ZCCHC8 | 0.999 | 0.154 |
| DIS3L | EXOSC9 | 0.999 | 0.186 |
| EXOSC8 | C1D | 0.998 | 0.56 |
| MTREX | EXOSC8 | 0.998 | 0.66 |
| EXOSC4 | HBS1L | 0.998 | 0.126 |
| MTREX | ZCCHC8 | 0.998 | 0.266 |
| MTREX | EXOSC6 | 0.998 | 0.472 |
| MPHOSPH6 | ZCCHC8 | 0.998 | 0.1 |
| EXOSC1 | MTREX | 0.997 | 0.636 |
| EXOSC2 | ZCCHC8 | 0.997 | 0.272 |
| MTREX | DIS3L | 0.997 | 0.13 |
| EXOSC5 | ZCCHC8 | 0.997 | 0.278 |
| EXOSC2 | HBS1L | 0.996 | 0.102 |
| NOL11 | WDR43 | 0.996 | 0.95 |
| WDR43 | UTP15 | 0.996 | 0.924 |
| EXOSC5 | HBS1L | 0.996 | 0.064 |
| DIS3L | EXOSC6 | 0.996 | 0.13 |
| DIS3L | EXOSC8 | 0.996 | 0.126 |
| WDR43 | MPHOSPH6 | 0.995 | 0.186 |
| MTREX | EXOSC9 | 0.995 | 0.824 |
| WDR43 | C1D | 0.995 | 0.67 |
| WDR75 | WDR43 | 0.994 | 0.91 |
| EXOSC8 | ZCCHC8 | 0.994 | 0.27 |
| C1D | HBS1L | 0.991 | 0.084 |
| EXOSC8 | HBS1L | 0.991 | 0.05 |
| NOL11 | UTP15 | 0.989 | 0.986 |
| EXOSC1 | ZCCHC8 | 0.988 | 0.17 |
| DIS3L | HBS1L | 0.987 | 0.13 |
| DIS3L | ZCCHC8 | 0.985 | 0.09 |
| UTP15 | MPHOSPH6 | 0.979 | 0.174 |
| WDR75 | C1D | 0.977 | 0.372 |
| WDR75 | NOL11 | 0.968 | 0.942 |
| UTP15 | C1D | 0.967 | 0.612 |
| NOL11 | MPHOSPH6 | 0.963 | 0.16 |
| WDR75 | EXOSC5 | 0.963 | 0.31 |
| WDR75 | UTP15 | 0.963 | 0.966 |
| MPHOSPH6 | HBS1L | 0.962 | 0.14 |
| EXOSC6 | ZCCHC8 | 0.96 | 0.194 |
| ZCCHC8 | EXOSC9 | 0.954 | 0.226 |
| NOL11 | C1D | 0.953 | 0.572 |
| MTREX | HBS1L | 0.943 | 0.118 |
| EXOSC6 | HBS1L | 0.942 | 0.09 |
| WDR75 | EXOSC2 | 0.941 | 0.244 |
| WDR43 | EXOSC5 | 0.938 | 0.246 |
| WDR43 | EXOSC2 | 0.925 | 0.324 |
| WDR75 | MPHOSPH6 | 0.924 | 0.198 |
| WDR43 | EXOSC4 | 0.914 | 0.372 |
| WDR75 | EXOSC3 | 0.91 | 0.384 |
| HBS1L | EXOSC9 | 0.9 | 0.112 |
| WDR43 | EXOSC3 | 0.897 | 0.448 |
| WDR43 | EXOSC9 | 0.889 | 0.512 |
| UTP15 | EXOSC5 | 0.888 | 0.544 |
| UTP4 | C1D | 0.882 | 0.376 |
| WDR43 | MTREX | 0.851 | 0.748 |
| ZCCHC8 | HBS1L | 0.817 | 0.058 |
| UTP4 | EXOSC4 | 0.8 | 0.408 |
| WDR75 | EXOSC4 | 0.753 | 0.404 |
| WDR75 | EXOSC7 | 0.738 | 0.272 |
| WDR43 | EXOSC1 | 0.735 | 0.456 |
| UTP4 | EXOSC5 | 0.731 | 0.27 |
| WDR75 | EXOSC8 | 0.728 | 0.362 |
| NOL11 | EXOSC4 | 0.712 | 0.39 |
| WDR43 | EXOSC7 | 0.71 | 0.238 |
| WDR75 | EXOSC1 | 0.69 | 0.494 |
| UTP4 | MPHOSPH6 | 0.676 | 0.168 |
| WDR43 | EXOSC8 | 0.67 | 0.358 |
| NOL11 | EXOSC5 | 0.642 | 0.402 |
| UTP15 | EXOSC4 | 0.641 | 0.34 |
| WDR43 | EXOSC6 | 0.641 | 0.188 |
| WDR75 | EXOSC9 | 0.603 | 0.326 |
| UTP15 | EXOSC2 | 0.56 | 0.544 |
| UTP4 | EXOSC2 | 0.537 | 0.356 |
| WDR43 | ZCCHC8 | 0.485 | 0.038 |
| WDR75 | EXOSC6 | 0.476 | 0.334 |
| UTP4 | ZCCHC8 | 0.425 | 0.03 |
| NOL11 | EXOSC2 | 0.363 | 0.424 |
| NOL11 | EXOSC6 | 0.347 | 0.282666666667 |
| WDR75 | DIS3L | 0.291 | 0.196 |
| UTP15 | EXOSC1 | 0.212 | 0.56 |
| NOL11 | EXOSC8 | 0.178 | 0.362 |
| UTP4 | DIS3L | 0.17 | 0.102 |
| UTP4 | MTREX | 0.165 | 0.65 |
| UTP15 | EXOSC8 | 0.162 | 0.528 |
| NOL11 | EXOSC1 | 0.16 | 0.294 |
| UTP15 | EXOSC6 | 0.146 | 0.344 |
| UTP15 | EXOSC3 | 0.14 | 0.522 |
| NOL11 | EXOSC9 | 0.134 | 0.562 |
| WDR43 | DIS3L | 0.131 | 0.084 |
| WDR75 | HBS1L | 0.125 | 0.076 |
| UTP4 | EXOSC8 | 0.117 | 0.372 |
| UTP4 | EXOSC1 | 0.098 | 0.53 |
| UTP15 | EXOSC7 | 0.09 | 0.546 |
| UTP4 | EXOSC6 | 0.072 | 0.344 |
| UTP15 | EXOSC9 | 0.062 | 0.66 |
| WDR75 | ZCCHC8 | 0.059 | 0.034 |
| NOL11 | EXOSC3 | 0.057 | 0.522 |
| UTP15 | DIS3L | 0.053 | 0.07 |
| NOL11 | EXOSC7 | 0.053 | 0.69 |
| UTP4 | EXOSC9 | 0.051 | 0.648 |
| UTP4 | EXOSC3 | 0.05 | 0.4 |
| UTP4 | EXOSC7 | 0.047 | 0.354 |
| NOL11 | DIS3L | 0.042 | 0.116 |
| NOL11 | ZCCHC8 | 0.041 | 0.058 |
| UTP15 | ZCCHC8 | 0.037 | 0.044 |
| WDR75 | MTREX | 0.011 | 0.488 |
| UTP15 | HBS1L | 0.009 | 0.104 |
| UTP4 | HBS1L | 0.009 | 0.066 |
| UTP15 | MTREX | 0.007 | 0.852 |
| NOL11 | MTREX | 0.007 | 0.834 |
| WDR43 | HBS1L | 0.007 | 0.02 |
| NOL11 | HBS1L | 0.003 | 0.036 |
Related Complexes
| Genename | Complexes |
|---|---|
| UTP4 | huMAP3_01549.1 huMAP3_01743.1 huMAP3_11250.1 huMAP3_14264.1 huMAP3_14364.1 |
| UTP15 | huMAP3_01743.1 huMAP3_14264.1 |
| ZCCHC8 | huMAP3_05382.1 huMAP3_14264.1 |
| WDR75 | huMAP3_01743.1 huMAP3_14264.1 |
| MPHOSPH6 | huMAP3_05382.1 huMAP3_14264.1 |
| EXOSC2 | huMAP3_05382.1 huMAP3_14264.1 |
| EXOSC1 | huMAP3_05194.1 huMAP3_05382.1 huMAP3_14264.1 |
| DIS3L | huMAP3_05382.1 huMAP3_14264.1 |
| EXOSC6 | huMAP3_05382.1 huMAP3_14264.1 |
| EXOSC8 | huMAP3_05382.1 huMAP3_14264.1 |
| EXOSC9 | huMAP3_05382.1 huMAP3_14264.1 |
| EXOSC3 | huMAP3_05382.1 huMAP3_14264.1 |
| EXOSC7 | huMAP3_05382.1 huMAP3_14264.1 |
| MTREX | huMAP3_05382.1 huMAP3_14264.1 |
| NOL11 | huMAP3_01743.1 huMAP3_14264.1 huMAP3_14364.1 |
| EXOSC4 | huMAP3_05382.1 huMAP3_14264.1 |
| WDR43 | huMAP3_01743.1 huMAP3_14264.1 |
| EXOSC5 | huMAP3_05382.1 huMAP3_14264.1 |
| C1D | huMAP3_05382.1 huMAP3_14264.1 |
| HBS1L | huMAP3_05382.1 huMAP3_14264.1 |