hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14281.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
AP3B1	AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)	5	UniProt NCBI
EPB41L3	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]	5	UniProt NCBI
AP3M2	AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B)	5	UniProt NCBI
AP3M1	AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin)	5	UniProt NCBI
AP3D1	AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)	5	UniProt NCBI
AP3S2	AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adaptor-related protein complex 3 subunit sigma-2) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b)	5	UniProt NCBI
AP3B2	AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:59	3.78260034975e-19	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	AP3 adaptor complex
GO:0035652	1.81186556753e-16	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	clathrin-coated vesicle cargo loading
GO:0035654	1.81186556753e-16	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	clathrin-coated vesicle cargo loading, AP-3-mediated
CORUM:652	2.70328971504e-16	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	AP3-BLOC1 complex
GO:0030123	2.17398353113e-15	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	AP-3 adaptor complex
GO:0048490	4.80196613796e-13	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	anterograde synaptic vesicle transport
GO:0099514	4.80196613796e-13	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	synaptic vesicle cytoskeletal transport
GO:0099517	4.80196613796e-13	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	synaptic vesicle transport along microtubule
GO:0035459	1.90309081662e-11	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	vesicle cargo loading
GO:0048489	2.34212799259e-11	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	synaptic vesicle transport
GO:0030119	4.19445139257e-11	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	AP-type membrane coat adaptor complex
GO:0097479	6.00683068035e-11	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	synaptic vesicle localization
KEGG:04142	1.14031378527e-10	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	Lysosome
GO:0047496	1.16151397783e-10	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	vesicle transport along microtubule
GO:0008089	1.35501997046e-10	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	anterograde axonal transport
GO:0098930	6.66661439204e-10	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	axonal transport
GO:0008088	1.29181280378e-09	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	axo-dendritic transport
GO:0099518	1.7529090922e-09	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	vesicle cytoskeletal trafficking
GO:0072384	3.69313015979e-09	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	organelle transport along microtubule
GO:0016183	4.60395405777e-09	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	synaptic vesicle coating
GO:0048475	1.30094786824e-08	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	coated membrane
GO:0030117	1.30094786824e-08	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	membrane coat
GO:0016185	3.22170910527e-08	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	synaptic vesicle budding from presynaptic endocytic zone membrane
GO:0070142	3.22170910527e-08	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	synaptic vesicle budding
GO:0010970	2.01869184354e-07	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	transport along microtubule
GO:0099111	4.1400936744e-07	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	microtubule-based transport
GO:0051650	7.31513734074e-07	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	establishment of vesicle localization
GO:0030705	8.74299375372e-07	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	cytoskeleton-dependent intracellular transport
GO:0051648	9.05470698191e-07	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	vesicle localization
GO:1903232	2.81160701714e-06	0.571428571429	AP3D1 AP3B1 AP3S2 AP3M1	melanosome assembly
GO:0060155	5.49646107354e-06	0.571428571429	AP3D1 AP3B1 AP3S2 AP3M1	platelet dense granule organization
GO:0005769	1.29667426464e-05	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	early endosome
GO:0007018	1.32595390184e-05	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	microtubule-based movement
GO:0016050	1.65028399687e-05	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	vesicle organization
CORUM:2307	2.05265451394e-05	0.285714285714	AP3D1 AP3S2	AP3D1-AP3S2 complex
WP:WP5408	3.00494857537e-05	0.428571428571	AP3M2 AP3B2 AP3D1	15q25 copy number variation
GO:0006901	4.7975405982e-05	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	vesicle coating
GO:0048753	5.39634524328e-05	0.571428571429	AP3D1 AP3B1 AP3S2 AP3M1	pigment granule organization
GO:0032438	5.39634524328e-05	0.571428571429	AP3D1 AP3B1 AP3S2 AP3M1	melanosome organization
GO:0033363	6.76004009067e-05	0.571428571429	AP3D1 AP3B1 AP3S2 AP3M1	secretory granule organization
GO:0051656	8.25239567577e-05	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	establishment of organelle localization
GO:0140238	0.000136293772339	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	presynaptic endocytosis
GO:0048488	0.000136293772339	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	synaptic vesicle endocytosis
GO:0036465	0.000288863510592	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	synaptic vesicle recycling
GO:0033059	0.000311468173387	0.571428571429	AP3D1 AP3B1 AP3S2 AP3M1	cellular pigmentation
GO:0051640	0.000360456132631	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	organelle localization
GO:0006900	0.000936913630871	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	vesicle budding from membrane
GO:0043473	0.000991064088366	0.571428571429	AP3D1 AP3B1 AP3S2 AP3M1	pigmentation
HP:0011125	0.00166533696614	0.285714285714	AP3D1 AP3B1	Abnormality of dermal melanosomes
GO:0007017	0.00377199817885	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	microtubule-based process
GO:0005768	0.00428640519627	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	endosome
GO:0099504	0.00432969529852	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	synaptic vesicle cycle
GO:0099003	0.0048515986555	0.571428571429	AP3M2 AP3B2 AP3S2 AP3D1	vesicle-mediated transport in synapse
HP:0001022	0.0199339480346	0.285714285714	AP3D1 AP3B1	Albinism
GO:0098796	0.0206938362537	0.857142857143	AP3B1 AP3S2 AP3B2 AP3D1 AP3M1 AP3M2	membrane protein complex
GO:0010256	0.0233487573869	0.714285714286	EPB41L3 AP3D1 AP3B1 AP3S2 AP3M1	endomembrane system organization
GO:0006897	0.0288491325703	0.714285714286	AP3M2 AP3B2 AP3M1 AP3S2 AP3D1	endocytosis
HP:0001107	0.0348446257606	0.285714285714	AP3D1 AP3B1	Ocular albinism

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
AP3M1	AP3B2	1.0	0.044	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
AP3B1	AP3M1	1.0	0.782	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM
AP3M1	AP3D1	1.0	0.794	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction
AP3B1	AP3M2	0.999	0.28	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction
EPB41L3	AP3M2	0.998		bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
AP3M2	AP3M1	0.998	0.636	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM
EPB41L3	AP3B1	0.996		bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
EPB41L3	AP3M1	0.995		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
AP3M2	AP3D1	0.995	0.604	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction
AP3B1	AP3D1	0.993	0.806	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM
AP3M1	AP3S2	0.991	0.068	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM
AP3B1	AP3B2	0.991	0.04	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
AP3M2	AP3B2	0.98	0.036	bioplex_WMM bioplex3_WMM WMM_only
AP3M2	AP3S2	0.978	0.074	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
EPB41L3	AP3D1	0.971		bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
AP3D1	AP3S2	0.938	0.136	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
AP3D1	AP3B2	0.921	0.038	bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
EPB41L3	AP3B2	0.913		bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
AP3B1	AP3S2	0.834	0.066	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
AP3S2	AP3B2	0.747	0.06	bioplex_WMM bioplex3_WMM WMM_only
EPB41L3	AP3S2	0.741		bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only

Related Complexes

Genename	Complexes
AP3B1	huMAP3_03149.1 huMAP3_03536.1 huMAP3_04281.1 huMAP3_06230.1 huMAP3_11077.1 huMAP3_11493.1 huMAP3_12157.1 huMAP3_12325.1 huMAP3_12813.1 huMAP3_13727.1 huMAP3_13786.1 huMAP3_14281.1 huMAP3_15082.1
EPB41L3	huMAP3_00103.1 huMAP3_07467.1 huMAP3_08647.1 huMAP3_09803.1 huMAP3_11077.1 huMAP3_11121.1 huMAP3_11493.1 huMAP3_12157.1 huMAP3_12325.1 huMAP3_12813.1 huMAP3_12829.1 huMAP3_14281.1 huMAP3_15082.1
AP3M2	huMAP3_03149.1 huMAP3_04148.1 huMAP3_04238.1 huMAP3_11493.1 huMAP3_12157.1 huMAP3_12325.1 huMAP3_12813.1 huMAP3_13727.1 huMAP3_14281.1 huMAP3_15082.1
AP3M1	huMAP3_03149.1 huMAP3_04148.1 huMAP3_04238.1 huMAP3_11493.1 huMAP3_12157.1 huMAP3_12325.1 huMAP3_12813.1 huMAP3_13727.1 huMAP3_14281.1 huMAP3_15082.1
AP3D1	huMAP3_03149.1 huMAP3_03536.1 huMAP3_04238.1 huMAP3_06230.1 huMAP3_11493.1 huMAP3_12157.1 huMAP3_12325.1 huMAP3_12813.1 huMAP3_13727.1 huMAP3_14281.1 huMAP3_15082.1
AP3S2	huMAP3_03149.1 huMAP3_03809.1 huMAP3_04148.1 huMAP3_04238.1 huMAP3_06631.1 huMAP3_07739.1 huMAP3_11493.1 huMAP3_12157.1 huMAP3_12325.1 huMAP3_12813.1 huMAP3_13727.1 huMAP3_14281.1 huMAP3_15082.1
AP3B2	huMAP3_03149.1 huMAP3_03536.1 huMAP3_04238.1 huMAP3_06230.1 huMAP3_11493.1 huMAP3_12157.1 huMAP3_12325.1 huMAP3_12813.1 huMAP3_13727.1 huMAP3_14281.1 huMAP3_15082.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_14281.1