hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14283.1
Complex Portal: CPX-22502
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ACY1 | Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) | 5 | UniProt NCBI |
| NUDT1 | Oxidized purine nucleoside triphosphate hydrolase (EC 3.6.1.56) (2-hydroxy-dATP diphosphatase) (7,8-dihydro-8-oxoguanine triphosphatase) (8-oxo-dGTPase) (Methylated purine nucleoside triphosphate hydrolase) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 1) (Nudix motif 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5579007 | 0.0249718442457 | 0.5 | ACY1 | Defective ACY1 causes encephalopathy |
| WP:WP4519 | 0.0435328773163 | 0.5 | ACY1 | Cerebral organic acidurias including diseases |
| KEGG:00220 | 0.0451122773679 | 0.5 | ACY1 | Arginine biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NUDT1 | ACY1 | 0.967 | 0.032 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
Related Complexes
| Genename | Complexes |
|---|---|
| ACY1 | huMAP3_10676.1 huMAP3_14283.1 huMAP3_14519.1 |
| NUDT1 | huMAP3_07863.1 huMAP3_10676.1 huMAP3_11181.1 huMAP3_11904.1 huMAP3_14283.1 huMAP3_15062.1 |