hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14286.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RABGEF1 | Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) | 5 | UniProt NCBI |
| RABEP1 | Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17) | 5 | UniProt NCBI |
| HGFAC | Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:50 | 1.02521027753e-05 | 0.666666666667 | RABEP1 RABGEF1 | RAB5-RABAPTIN5-RABEX5 complex |
| REAC:R-HSA-8854214 | 0.00504394814871 | 0.666666666667 | RABEP1 RABGEF1 | TBC/RABGAPs |
| REAC:R-HSA-9007101 | 0.0392065258044 | 0.666666666667 | RABEP1 RABGEF1 | Rab regulation of trafficking |
| CORUM:1090 | 0.0499402709677 | 0.333333333333 | RABEP1 | APLG1-Rababtin5 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RABGEF1 | RABEP1 | 0.998 | 0.314 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 boldt_WMM |
| HGFAC | RABGEF1 | 0.949 | 0.012 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| HGFAC | RABEP1 | 0.218 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes