hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14305.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UBA52 | Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)] | 5 | UniProt NCBI |
| METAP1 | Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1) | 5 | UniProt NCBI |
| SAMD1 | Sterile alpha motif domain-containing protein 1 (SAM domain-containing protein 1) (Atherin) | 5 | UniProt NCBI |
| CDC6 | Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP466 | 0.002190823719 | 0.5 | UBA52 CDC6 | DNA replication |
| REAC:R-HSA-68949 | 0.0246065982605 | 0.5 | UBA52 CDC6 | Orc1 removal from chromatin |
| REAC:R-HSA-69017 | 0.0253175164514 | 0.5 | UBA52 CDC6 | CDK-mediated phosphorylation and removal of Cdc6 |
| REAC:R-HSA-69052 | 0.0407325822829 | 0.5 | UBA52 CDC6 | Switching of origins to a post-replicative state |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SAMD1 | CDC6 | 0.946 | 0.054 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| METAP1 | UBA52 | 0.934 | 0.682833333333 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| SAMD1 | METAP1 | 0.918 | 0.054 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| SAMD1 | UBA52 | 0.911 | 0.428 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| CDC6 | UBA52 | 0.888 | 0.366461379717 | hein_WMM bioplex3_WMM hein () |
Related Complexes