hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14308.1
Complex Portal: CPX-16207
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZDHHC5 | Palmitoyltransferase ZDHHC5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375) | 5 | UniProt NCBI |
| PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha) | 5 | UniProt NCBI |
| TMEFF1 | Tomoregulin-1 (TR-1) (H7365) (Transmembrane protein with EGF-like and one follistatin-like domain) | 5 | UniProt NCBI |
| ZDHHC8 | Palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378) | 5 | UniProt NCBI |
| CLDND1 | Claudin domain-containing protein 1 (Membrane protein GENX-3745) | 4 | UniProt NCBI |
| MAN1A1 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Man(9)-alpha-mannosidase) (Man9-mannosidase) (Mannosidase alpha class 1A member 1) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) | 5 | UniProt NCBI |
| CHAC1 | Glutathione-specific gamma-glutamylcyclotransferase 1 (Gamma-GCG 1) (EC 4.3.2.7) (Blocks Notch protein) (Botch) (Cation transport regulator-like protein 1) | 5 | UniProt NCBI |
| GOLGA7 | Golgin subfamily A member 7 (Golgi complex-associated protein of 16 kDa) | 5 | UniProt NCBI |
| L1TD1 | LINE-1 type transposase domain-containing protein 1 (ES cell-associated protein 11) | 4 | UniProt NCBI |
| GOLGA7B | Golgin subfamily A member 7B | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9694548 | 0.000247991939921 | 0.333333333333 | ZDHHC8 ZDHHC5 GOLGA7 | Maturation of spike protein |
| REAC:R-HSA-9694635 | 0.000882703573715 | 0.333333333333 | ZDHHC8 ZDHHC5 GOLGA7 | Translation of Structural Proteins |
| REAC:R-HSA-9772573 | 0.00142112451214 | 0.333333333333 | ZDHHC8 ZDHHC5 GOLGA7 | Late SARS-CoV-2 Infection Events |
| GO:0018345 | 0.00778531456229 | 0.333333333333 | ZDHHC8 ZDHHC5 GOLGA7 | protein palmitoylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZDHHC5 | CLDND1 | 1.0 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| GOLGA7 | CLDND1 | 0.999 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ZDHHC8 | CLDND1 | 0.999 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| MAN1A1 | CLDND1 | 0.998 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ZDHHC5 | GOLGA7B | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CLDND1 | GOLGA7B | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CLDND1 | L1TD1 | 0.987 | 0.04 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CLDND1 | PI4K2A | 0.984 | 0.092 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZDHHC8 | ZDHHC5 | 0.974 | 0.056 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| TMEFF1 | CLDND1 | 0.972 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| GOLGA7 | ZDHHC5 | 0.971 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZDHHC8 | GOLGA7 | 0.967 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only | |
| MAN1A1 | ZDHHC8 | 0.932 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMEFF1 | GOLGA7 | 0.922 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZDHHC8 | GOLGA7B | 0.902 | bioplex3_WMM WMM_only | ||
| ZDHHC8 | L1TD1 | 0.902 | 0.064 | bioplex3_WMM WMM_only | |
| CHAC1 | L1TD1 | 0.902 | bioplex3_WMM WMM_only | ||
| ZDHHC8 | PI4K2A | 0.902 | 0.05 | bioplex3_WMM WMM_only | |
| L1TD1 | GOLGA7B | 0.902 | bioplex3_WMM WMM_only | ||
| MAN1A1 | GOLGA7 | 0.899 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only | |
| MAN1A1 | ZDHHC5 | 0.876 | 0.0520588235294 | bioplex_WMM bioplex3_WMM WMM_only | |
| GOLGA7B | PI4K2A | 0.869 | bioplex3_WMM WMM_only | ||
| TMEFF1 | ZDHHC5 | 0.858 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZDHHC5 | L1TD1 | 0.73 | 0.062 | bioplex3_WMM WMM_only | |
| GOLGA7 | GOLGA7B | 0.73 | bioplex3_WMM WMM_only | ||
| MAN1A1 | GOLGA7B | 0.654 | bioplex3_WMM WMM_only | ||
| GOLGA7 | PI4K2A | 0.494 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only | |
| L1TD1 | PI4K2A | 0.401 | 0.1 | bioplex3_WMM WMM_only | |
| MAN1A1 | L1TD1 | 0.389 | 0.068 | bioplex3_WMM WMM_only | |
| GOLGA7 | L1TD1 | 0.388 | 0.046 | bioplex3_WMM WMM_only | |
| ZDHHC5 | PI4K2A | 0.356 | 0.094 | bioplex3_WMM WMM_only | |
| MAN1A1 | PI4K2A | 0.117 | 0.07 | bioplex3_WMM WMM_only |
Related Complexes