hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14317.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
SPIDR | DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair) | 5 | UniProt   NCBI |
SWSAP1 | ATPase SWSAP1 (SWIM-type zinc finger 7-associated protein 1) (SWS1-associated protein 1) (ZSWIM7-associated protein 1) (ZSWIM7AP1) | 5 | UniProt   NCBI |
PLA2G10 | Group 10 secretory phospholipase A2 (EC 3.1.1.4) (Group X secretory phospholipase A2) (GX sPLA2) (sPLA2-X) (Phosphatidylcholine 2-acylhydrolase 10) | 5 | UniProt   NCBI |
ZSWIM7 | Zinc finger SWIM domain-containing protein 7 (SWIM domain-containing and Srs2-interacting protein 1 homolog) (SWIM-type zinc finger domain-containing protein 7) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  GO:0097196 | 0.0028092043205 | 0.5 | SWSAP1 ZSWIM7 | Shu complex |
  HP:0005625 | 0.00303997345979 | 0.5 | SPIDR ZSWIM7 | Osteoporosis of vertebrae |
  HP:0040161 | 0.00350734148159 | 0.5 | SPIDR ZSWIM7 | Localized osteoporosis |
  HP:0011969 | 0.00701084122037 | 0.5 | SPIDR ZSWIM7 | Elevated circulating luteinizing hormone level |
  HP:0010464 | 0.00771122114953 | 0.5 | SPIDR ZSWIM7 | Streak ovary |
  HP:0000133 | 0.0135443934278 | 0.5 | SPIDR ZSWIM7 | Gonadal dysgenesis |
  HP:0008232 | 0.0135443934278 | 0.5 | SPIDR ZSWIM7 | Elevated circulating follicle stimulating hormone level |
  HP:0002225 | 0.021003726131 | 0.5 | SPIDR ZSWIM7 | Sparse pubic hair |
  HP:0008214 | 0.0234332085093 | 0.5 | SPIDR ZSWIM7 | Decreased serum estradiol |
  HP:0100133 | 0.0234332085093 | 0.5 | SPIDR ZSWIM7 | Abnormality of the pubic hair |
  HP:0025132 | 0.034474601612 | 0.5 | SPIDR ZSWIM7 | Abnormal circulating estrogen level |
  HP:0025133 | 0.034474601612 | 0.5 | SPIDR ZSWIM7 | Abnormal serum estradiol |
  HP:0030345 | 0.036003514982 | 0.5 | SPIDR ZSWIM7 | Abnormal circulating luteinizing hormone concentration |
  HP:0009888 | 0.0476300363671 | 0.5 | SPIDR ZSWIM7 | Abnormality of secondary sexual hair |
  HP:0030346 | 0.0476300363671 | 0.5 | SPIDR ZSWIM7 | Abnormal circulating follicle-stimulating hormone concentration |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 SWSAP1 |  ZSWIM7 | 1.0 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 SPIDR |  SWSAP1 | 0.996 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 ZSWIM7 |  PLA2G10 | 0.994 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 SPIDR |  PLA2G10 | 0.992 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 SPIDR |  ZSWIM7 | 0.984 |            | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     WMM_only     |
 SWSAP1 |  PLA2G10 | 0.965 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes