hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14320.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| USP24 | Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) | 5 | UniProt NCBI |
| BMX | Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) | 5 | UniProt NCBI |
| CASP7 | Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] | 5 | UniProt NCBI |
| CC2D1B | Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-111465 | 0.006081926491 | 0.5 | CASP7 BMX | Apoptotic cleavage of cellular proteins |
| REAC:R-HSA-75153 | 0.0120053783973 | 0.5 | CASP7 BMX | Apoptotic execution phase |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| USP24 | BMX | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| BMX | CC2D1B | 0.952 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CASP7 | CC2D1B | 0.943 | 0.082 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| USP24 | CC2D1B | 0.219 | 0.086 | bioplex_WMM bioplex3_WMM fraction |
Related Complexes