hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14339.1

Complex Portal: CPX-19467

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
PDK1	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)	5	UniProt NCBI
PDHA2	Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (EC 1.2.4.1) (PDHE1-A type II)	5	UniProt NCBI
PDHX	Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX)	5	UniProt NCBI
PDK3	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3)	5	UniProt NCBI
PDK2	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)	5	UniProt NCBI
CA5A	Carbonic anhydrase 5A, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VA) (Carbonic anhydrase VA) (CA-VA)	5	UniProt NCBI
STAT5A	Signal transducer and activator of transcription 5A	5	UniProt NCBI
PDHA1	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)	5	UniProt NCBI
STAT5B	Signal transducer and activator of transcription 5B	5	UniProt NCBI
PDHB	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHE1-B) (EC 1.2.4.1)	5	UniProt NCBI
FOXD4	Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead-related transcription factor 5) (FREAC-5) (Myeloid factor-alpha)	4	UniProt NCBI
DLAT	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (M2 antigen complex 70 kDa subunit) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)	5	UniProt NCBI
PDK4	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-204174	3.45842818368e-17	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	Regulation of pyruvate dehydrogenase (PDH) complex
GO:0006086	7.01157996122e-17	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	acetyl-CoA biosynthetic process from pyruvate
REAC:R-HSA-70268	6.13380009356e-15	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	Pyruvate metabolism
GO:0006085	1.1344382768e-14	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	acetyl-CoA biosynthetic process
REAC:R-HSA-5362517	3.09678616092e-14	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	Signaling by Retinoic Acid
GO:0006084	3.82879788951e-13	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	acetyl-CoA metabolic process
REAC:R-HSA-71406	4.00965162968e-13	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	Pyruvate metabolism and Citric Acid (TCA) cycle
GO:0071616	7.3246383038e-12	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	acyl-CoA biosynthetic process
GO:0035384	7.3246383038e-12	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	thioester biosynthetic process
GO:0034033	4.26309060351e-11	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine nucleoside bisphosphate biosynthetic process
GO:0034030	4.26309060351e-11	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	ribonucleoside bisphosphate biosynthetic process
GO:0033866	4.26309060351e-11	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	nucleoside bisphosphate biosynthetic process
GO:0006790	2.15583533767e-10	0.818181818182	PDHX STAT5B PDK2 PDHA2 STAT5A PDHA1 PDK4 PDK1 PDK3	sulfur compound metabolic process
GO:0006637	1.38270094604e-09	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	acyl-CoA metabolic process
GO:0035383	1.38270094604e-09	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	thioester metabolic process
REAC:R-HSA-1428517	2.00705008256e-09	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	The citric acid (TCA) cycle and respiratory electron transport
GO:0006090	3.6404756475e-09	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	pyruvate metabolic process
GO:0034032	7.35077323208e-09	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine nucleoside bisphosphate metabolic process
GO:0033875	7.35077323208e-09	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	ribonucleoside bisphosphate metabolic process
GO:0033865	7.35077323208e-09	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	nucleoside bisphosphate metabolic process
GO:0010510	8.68316823302e-09	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0050812	8.68316823302e-09	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of acyl-CoA biosynthetic process
REAC:R-HSA-9006931	2.9203695774e-08	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	Signaling by Nuclear Receptors
GO:0004740	4.33992010508e-08	0.363636363636	PDK1 PDK4 PDK3 PDK2	pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0044272	6.33381147463e-08	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	sulfur compound biosynthetic process
GO:0009152	2.29735542097e-07	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine ribonucleotide biosynthetic process
GO:0045254	3.03561565333e-07	0.363636363636	PDHA2 PDK2 PDHA1 PDHX	pyruvate dehydrogenase complex
GO:0005967	3.03561565333e-07	0.363636363636	PDHA2 PDK2 PDHA1 PDHX	mitochondrial pyruvate dehydrogenase complex
GO:0009260	3.41176421947e-07	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	ribonucleotide biosynthetic process
GO:0046390	4.38791767201e-07	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	ribose phosphate biosynthetic process
GO:0006164	7.92926868251e-07	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine nucleotide biosynthetic process
GO:0072522	9.5548657402e-07	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine-containing compound biosynthetic process
GO:0006082	1.16850934856e-06	0.818181818182	PDHX STAT5B PDK2 PDHA2 STAT5A PDHA1 PDK4 PDK1 PDK3	organic acid metabolic process
GO:0009165	1.68116745427e-06	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	nucleotide biosynthetic process
GO:0042762	1.81927560642e-06	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of sulfur metabolic process
GO:1901293	1.92283626743e-06	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	nucleoside phosphate biosynthetic process
GO:0005759	2.39486168038e-06	0.727272727273	PDHX PDK2 PDHA2 PDHA1 PDK3 PDK4 PDK1 CA5A	mitochondrial matrix
KEGG:05415	6.28226176485e-06	0.454545454545	PDHA1 PDHA2 PDK4 PDK3 PDK2	Diabetic cardiomyopathy
GO:0044281	8.97562162963e-06	0.909090909091	PDHX STAT5B PDK2 PDHA2 STAT5A PDK3 PDHA1 PDK4 PDK1 CA5A	small molecule metabolic process
GO:1900371	1.18026398065e-05	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of purine nucleotide biosynthetic process
GO:0030808	1.18026398065e-05	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of nucleotide biosynthetic process
GO:0009150	3.0307186542e-05	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine ribonucleotide metabolic process
WP:WP4206	3.7482998324e-05	0.272727272727	PDK1 PDHA1 PDHA2	Hereditary leiomyomatosis and renal cell carcinoma pathway
GO:0009259	3.77313638489e-05	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	ribonucleotide metabolic process
GO:0019693	4.8641717733e-05	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	ribose phosphate metabolic process
WP:WP581	5.05933326484e-05	0.272727272727	PDK1 STAT5A STAT5B	EPO receptor signaling
GO:0006163	0.000116835697795	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine nucleotide metabolic process
GO:0072521	0.000155563544425	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	purine-containing compound metabolic process
REAC:R-HSA-389661	0.000187302344386	0.272727272727	PDHA2 PDHA1 PDHX	Glyoxylate metabolism and glycine degradation
REAC:R-HSA-162582	0.000201719438232	0.818181818182	PDHX STAT5B PDK2 PDHA2 STAT5A PDHA1 PDK4 PDK1 PDK3	Signal Transduction
GO:0032787	0.000208218838948	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	monocarboxylic acid metabolic process
GO:0009117	0.000222606811508	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	nucleotide metabolic process
GO:0006753	0.000245775154223	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	nucleoside phosphate metabolic process
GO:0090407	0.000275374979405	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	organophosphate biosynthetic process
GO:0004738	0.000316805542726	0.272727272727	PDHA2 PDHA1 PDHX	pyruvate dehydrogenase activity
WP:WP528	0.00053693805875	0.181818181818	PDHA2 PDHA1	Acetylcholine synthesis
GO:0055086	0.000564495741932	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	nucleobase-containing small molecule metabolic process
GO:1901137	0.000660821036188	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	carbohydrate derivative biosynthetic process
KEGG:05230	0.000754370008701	0.272727272727	PDK1 PDHA1 PDHA2	Central carbon metabolism in cancer
REAC:R-HSA-9645135	0.000799893187683	0.181818181818	STAT5A STAT5B	STAT5 Activation
REAC:R-HSA-9027283	0.00133260792819	0.181818181818	STAT5A STAT5B	Erythropoietin activates STAT5
REAC:R-HSA-1430728	0.00140104828406	0.727272727273	PDHX PDK2 PDHA2 PDHA1 PDK3 PDK4 PDK1 CA5A	Metabolism
WP:WP4255	0.0015449623769	0.272727272727	PDK1 STAT5A STAT5B	Non small cell lung cancer
WP:WP5050	0.00241126491604	0.181818181818	PDK1 PDHA1	TCA cycle in senescence
KEGG:04066	0.00243761561614	0.272727272727	PDK1 PDHA1 PDHA2	HIF-1 signaling pathway
REAC:R-HSA-9020958	0.00279617904977	0.181818181818	STAT5A STAT5B	Interleukin-21 signaling
WP:WP3925	0.00294376640307	0.272727272727	PDHX PDHA1 PDK4	Amino acid metabolism
GO:0019752	0.00300650667516	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	carboxylic acid metabolic process
GO:0010906	0.00312623068186	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of glucose metabolic process
WP:WP5063	0.00353361833038	0.181818181818	STAT5A STAT5B	FOXP3 in COVID 19
GO:0043436	0.00355450176754	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	oxoacid metabolic process
GO:0019217	0.00360844884004	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of fatty acid metabolic process
REAC:R-HSA-9702518	0.00372670794354	0.181818181818	STAT5A STAT5B	STAT5 activation downstream of FLT3 ITD mutants
REAC:R-HSA-8985947	0.00372670794354	0.181818181818	STAT5A STAT5B	Interleukin-9 signaling
GO:1900542	0.00386939458835	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of purine nucleotide metabolic process
KEGG:00785	0.00398991378584	0.181818181818	PDHA2 PDHA1	Lipoic acid metabolism
GO:0006140	0.00414418736138	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of nucleotide metabolic process
REAC:R-HSA-2586552	0.00478951429206	0.181818181818	STAT5A STAT5B	Signaling by Leptin
REAC:R-HSA-9020558	0.00478951429206	0.181818181818	STAT5A STAT5B	Interleukin-2 signaling
WP:WP22	0.00486811003538	0.181818181818	STAT5A STAT5B	IL 9 signaling pathway
GO:0043604	0.00517234338248	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	amide biosynthetic process
HP:0500231	0.00714132578593	0.181818181818	PDHX PDHA1	Abnormal CSF pyruvate family amino acid concentration
WP:WP205	0.0072664591732	0.181818181818	STAT5A STAT5B	IL 7 signaling pathway
REAC:R-HSA-1170546	0.00876996466453	0.181818181818	STAT5A STAT5B	Prolactin receptor signaling
HP:0003348	0.0103212579368	0.272727272727	PDHX CA5A PDHA1	Hyperalaninemia
REAC:R-HSA-8983432	0.0103602481019	0.181818181818	STAT5A STAT5B	Interleukin-15 signaling
REAC:R-HSA-9703648	0.0103602481019	0.181818181818	STAT5A STAT5B	Signaling by FLT3 ITD and TKD mutants
HP:0010916	0.0108416069954	0.272727272727	PDHX CA5A PDHA1	Abnormal circulating alanine concentration
HP:0010915	0.0108416069954	0.272727272727	PDHX CA5A PDHA1	Abnormal circulating pyruvate family amino acid concentration
GO:0019637	0.0112413101244	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	organophosphate metabolic process
KEGG:00020	0.0112881061339	0.181818181818	PDHA2 PDHA1	Citrate cycle (TCA cycle)
KEGG:01210	0.0112881061339	0.181818181818	PDHA2 PDHA1	2-Oxocarboxylic acid metabolism
REAC:R-HSA-9703465	0.0159192181681	0.181818181818	STAT5A STAT5B	Signaling by FLT3 fusion proteins
REAC:R-HSA-1839117	0.0159192181681	0.181818181818	STAT5A STAT5B	Signaling by cytosolic FGFR1 fusion mutants
WP:WP4149	0.0159763787346	0.181818181818	STAT5A STAT5B	White fat cell differentiation
HP:0033108	0.0163236887013	0.272727272727	PDHX CA5A PDHA1	Abnormal circulating proteinogenic amino acid derivative concentration
WP:WP3972	0.0173006372103	0.181818181818	STAT5A STAT5B	PDGFR beta pathway
GO:1901135	0.0179050392937	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	carbohydrate derivative metabolic process
REAC:R-HSA-9669938	0.0180343727667	0.181818181818	STAT5A STAT5B	Signaling by KIT in disease
REAC:R-HSA-9670439	0.0180343727667	0.181818181818	STAT5A STAT5B	Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
GO:0010565	0.0196054888171	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of cellular ketone metabolic process
HP:0002928	0.0213888128664	0.181818181818	PDHX PDHA1	Decreased activity of the pyruvate dehydrogenase complex
WP:WP5358	0.0215858775392	0.181818181818	STAT5A STAT5B	JAK STAT signaling in the regulation of Beta cells
GO:0005739	0.0221223946978	0.727272727273	PDHX PDK2 PDHA2 PDHA1 PDK3 PDK4 PDK1 CA5A	mitochondrion
REAC:R-HSA-9006335	0.022656954619	0.181818181818	STAT5A STAT5B	Signaling by Erythropoietin
KEGG:00620	0.0233077837061	0.181818181818	PDHA2 PDHA1	Pyruvate metabolism
WP:WP127	0.0247024437992	0.181818181818	STAT5A STAT5B	IL 5 signaling pathway
GO:0097411	0.0257510396046	0.181818181818	PDK1 PDK3	hypoxia-inducible factor-1alpha signaling pathway
GO:0034654	0.0273693774831	0.909090909091	PDHX STAT5B PDK2 PDHA2 STAT5A PDHA1 FOXD4 PDK4 PDK1 PDK3	nucleobase-containing compound biosynthetic process
REAC:R-HSA-982772	0.0278014860056	0.181818181818	STAT5A STAT5B	Growth hormone receptor signaling
WP:WP49	0.0280261977151	0.181818181818	STAT5A STAT5B	IL 2 signaling pathway
WP:WP2203	0.0297656085673	0.181818181818	STAT5A STAT5B	Thymic stromal lymphopoietin TSLP signaling pathway
REAC:R-HSA-8854691	0.0305690780225	0.181818181818	STAT5A STAT5B	Interleukin-20 family signaling
GO:0018130	0.0327201680984	0.909090909091	PDHX STAT5B PDK2 PDHA2 STAT5A PDHA1 FOXD4 PDK4 PDK1 PDK3	heterocycle biosynthetic process
GO:0019438	0.0330622518626	0.909090909091	PDHX STAT5B PDK2 PDHA2 STAT5A PDHA1 FOXD4 PDK4 PDK1 PDK3	aromatic compound biosynthetic process
REAC:R-HSA-9705462	0.0334666719879	0.181818181818	STAT5A STAT5B	Inactivation of CSF3 (G-CSF) signaling
REAC:R-HSA-1839124	0.0364941063676	0.181818181818	STAT5A STAT5B	FGFR1 mutant receptor activation
REAC:R-HSA-9682385	0.0364941063676	0.181818181818	STAT5A STAT5B	FLT3 signaling in disease
GO:0043603	0.0382274839441	0.636363636364	PDHX PDK2 PDHA2 PDHA1 PDK4 PDK1 PDK3	amide metabolic process
WP:WP5220	0.0392354234732	0.181818181818	PDHX PDHA1	Metabolic reprogramming in pancreatic cancer
GO:0006006	0.0399279910051	0.363636363636	PDK1 PDK4 PDK3 PDK2	glucose metabolic process
REAC:R-HSA-186763	0.0429378509001	0.181818181818	STAT5A STAT5B	Downstream signal transduction
KEGG:05221	0.0438742392764	0.181818181818	STAT5A STAT5B	Acute myeloid leukemia
GO:1901362	0.0438918850918	0.909090909091	PDHX STAT5B PDK2 PDHA2 STAT5A PDHA1 FOXD4 PDK4 PDK1 PDK3	organic cyclic compound biosynthetic process
WP:WP286	0.0455332057338	0.181818181818	STAT5A STAT5B	IL 3 signaling pathway
KEGG:04917	0.0484301779192	0.181818181818	STAT5A STAT5B	Prolactin signaling pathway
KEGG:00010	0.0484301779192	0.181818181818	PDHA2 PDHA1	Glycolysis / Gluconeogenesis
REAC:R-HSA-9674555	0.0498990220101	0.181818181818	STAT5A STAT5B	Signaling by CSF3 (G-CSF)
GO:0006109	0.0499091508905	0.363636363636	PDK1 PDK4 PDK3 PDK2	regulation of carbohydrate metabolic process
CORUM:2023	0.049976851631	0.0909090909091	STAT5A	STAT5A homodimer complex
CORUM:2013	0.049976851631	0.0909090909091	STAT5B	STAT5B homodimer complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
PDHA1	PDHB	1.0	0.958	structurally_consistent (dimer)
STAT5A	PDHA1	1.0	0.158
STAT5A	DLAT	1.0	0.086
PDK3	STAT5A	1.0	0.03
PDK3	FOXD4	1.0		structurally_consistent (Q15119) structurally_consistent (dimer)
PDHA1	DLAT	1.0	0.718
PDHB	DLAT	1.0	0.694
PDK3	DLAT	0.999	0.118	structurally_consistent (dimer)
STAT5A	PDHB	0.999	0.124
PDK1	PDK2	0.999	0.058	structurally_consistent (dimer)
PDK3	PDK1	0.999	0.278	structurally_consistent (dimer)
STAT5A	PDHX	0.999	0.04
PDK3	PDHB	0.999	0.124	structurally_consistent (dimer)
STAT5A	STAT5B	0.999	0.768	structurally_consistent (dimer)
PDHX	PDHA1	0.998	0.684
PDK3	PDHX	0.998	0.06	structurally_consistent (dimer)
PDHX	DLAT	0.997	0.652
PDK3	PDHA1	0.997	0.18	structurally_consistent (dimer)
PDHA1	PDK2	0.996	0.204
PDK3	PDK2	0.996	0.088	structurally_consistent (dimer)
FOXD4	PDHA1	0.996
PDK1	PDHA1	0.996	0.29
PDK2	DLAT	0.994	0.236	structurally_consistent (dimer)
PDHX	PDK2	0.994	0.07
FOXD4	PDK2	0.994		structurally_consistent (P11177) structurally_consistent (dimer)
STAT5B	PDHX	0.993	0.078
PDHX	PDHB	0.991	0.568
STAT5B	PDHA1	0.989	0.11
PDK4	PDK3	0.987		structurally_consistent (dimer)
PDK3	PDHA2	0.986		structurally_consistent (dimer)
FOXD4	PDHX	0.986		mutually_exclusive (Q15120)
FOXD4	PDHB	0.984		structurally_consistent (Q15119) structurally_consistent (dimer)
PDK1	PDHX	0.984	0.218
FOXD4	DLAT	0.982		structurally_consistent (Q15119)
STAT5B	PDHB	0.981	0.086
FOXD4	PDK1	0.977		structurally_consistent (Q15119)
PDK1	PDHB	0.964	0.429538461538
PDHB	PDK2	0.957	0.354	structurally_consistent (dimer)
PDHA1	CA5A	0.947
PDK4	PDK2	0.927		mutually_exclusive (Q15120)
PDK1	DLAT	0.924	0.3708
STAT5B	DLAT	0.88	0.092
PDHA2	PDHB	0.844		structurally_consistent (dimer)
DLAT	CA5A	0.816
PDK3	STAT5B	0.789	0.024
PDK4	PDK1	0.713
PDHB	CA5A	0.647
PDHA2	DLAT	0.587		structurally_consistent (Q15120)
PDHA2	PDHX	0.505
PDHX	CA5A	0.469
PDHA2	PDHA1	0.313		mutually_exclusive (P11177)
STAT5A	PDK2	0.239	0.110288
PDHA2	PDK1	0.168		structurally_consistent (Q15120)
STAT5B	PDK2	0.143	0.06
PDHA2	PDK2	0.143		structurally_consistent (Q15120)
PDK4	PDHA1	0.007		structurally_consistent (dimer)
PDK4	DLAT	0.005

Related Complexes

Genename	Complexes
PDK1	huMAP3_04704.1 huMAP3_04919.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
PDHA2	huMAP3_02577.1 huMAP3_11877.1 huMAP3_12045.1 huMAP3_12248.1 huMAP3_13797.1 huMAP3_13948.1 huMAP3_14339.1 huMAP3_14864.1
PDHX	huMAP3_04704.1 huMAP3_04919.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
PDK3	huMAP3_00016.1 huMAP3_04704.1 huMAP3_04919.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
PDK2	huMAP3_04919.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
CA5A	huMAP3_11377.1 huMAP3_11473.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_12936.1 huMAP3_14339.1 huMAP3_14864.1 huMAP3_15110.1
STAT5A	huMAP3_03752.1 huMAP3_05442.1 huMAP3_07514.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
PDHA1	huMAP3_04704.1 huMAP3_04919.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
STAT5B	huMAP3_03752.1 huMAP3_04704.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
PDHB	huMAP3_04704.1 huMAP3_04919.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
FOXD4	huMAP3_01427.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1
DLAT	huMAP3_04919.1 huMAP3_07514.1 huMAP3_08216.1 huMAP3_09761.1 huMAP3_10412.1 huMAP3_10899.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1
PDK4	huMAP3_00016.1 huMAP3_11877.1 huMAP3_12248.1 huMAP3_14339.1 huMAP3_14864.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_14339.1

Complex Portal: CPX-19467