hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14348.1
Complex Portal: CPX-13587
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ACBD7 | Acyl-CoA-binding domain-containing protein 7 | 3 | UniProt NCBI |
| ACOX1 | Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Peroxisomal fatty acyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) (SCOX) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain] | 5 | UniProt NCBI |
| ACAA1 | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1941 | 3.39807600054e-06 | 0.666666666667 | ACOX1 ACAA1 | Peroxisomal beta oxidation of tetracosanoyl CoA |
| REAC:R-HSA-9033500 | 0.000102258192243 | 0.666666666667 | ACOX1 ACAA1 | TYSND1 cleaves peroxisomal proteins |
| KEGG:00592 | 0.00011671046881 | 0.666666666667 | ACOX1 ACAA1 | alpha-Linolenic acid metabolism |
| WP:WP4721 | 0.000135842423213 | 0.666666666667 | ACOX1 ACAA1 | Eicosanoid metabolism via lipooxygenases LOX |
| KEGG:01040 | 0.00017617774418 | 0.666666666667 | ACOX1 ACAA1 | Biosynthesis of unsaturated fatty acids |
| WP:WP4719 | 0.000286309588192 | 0.666666666667 | ACOX1 ACAA1 | Eicosanoid metabolism via cyclooxygenases COX |
| KEGG:00071 | 0.000594396930969 | 0.666666666667 | ACOX1 ACAA1 | Fatty acid degradation |
| KEGG:01212 | 0.000933081380813 | 0.666666666667 | ACOX1 ACAA1 | Fatty acid metabolism |
| KEGG:03320 | 0.00130273084965 | 0.666666666667 | ACOX1 ACAA1 | PPAR signaling pathway |
| KEGG:04146 | 0.00153460242624 | 0.666666666667 | ACOX1 ACAA1 | Peroxisome |
| WP:WP3942 | 0.00155728900053 | 0.666666666667 | ACOX1 ACAA1 | PPAR signaling pathway |
| GO:0016401 | 0.00421361424067 | 0.666666666667 | ACOX1 ACAA1 | palmitoyl-CoA oxidase activity |
| REAC:R-HSA-9033241 | 0.00767507889467 | 0.666666666667 | ACOX1 ACAA1 | Peroxisomal protein import |
| GO:0003997 | 0.0140440992017 | 0.666666666667 | ACOX1 ACAA1 | acyl-CoA oxidase activity |
| GO:0016634 | 0.0294899169624 | 0.666666666667 | ACOX1 ACAA1 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor |
| WP:WP2882 | 0.0351361093338 | 0.666666666667 | ACOX1 ACAA1 | Nuclear receptors meta pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ACBD7 | ACOX1 | 0.98 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ACOX1 | ACAA1 | 0.973 | 0.214 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes