hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
UTY	Histone demethylase UTY (EC 1.14.11.68) (Ubiquitously-transcribed TPR protein on the Y chromosome) (Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase UTY)	5	UniProt NCBI
MTIF3	Translation initiation factor IF-3, mitochondrial (IF-3(Mt)) (IF-3Mt) (IF3(mt)) (IF3mt)	5	UniProt NCBI
PAGR1	PAXIP1-associated glutamate-rich protein 1 (Glutamate-rich coactivator interacting with SRC1) (GAS) (PAXIP1-associated protein 1) (PTIP-associated protein 1)	5	UniProt NCBI
KMT2D	Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)	5	UniProt NCBI
PAXIP1	PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0044666	4.33992010508e-08	0.8	UTY KMT2D PAXIP1 PAGR1	MLL3/4 complex
CORUM:6467	2.35251050842e-07	0.6	PAGR1 PAXIP1 KMT2D	MLL4 complex
REAC:R-HSA-9772755	3.07163147334e-05	0.6	PAGR1 PAXIP1 KMT2D	Formation of WDR5-containing histone-modifying complexes
WP:WP4949	6.85359532624e-05	0.6	PAGR1 PAXIP1 KMT2D	16p11 2 proximal deletion syndrome
GO:0035097	8.33174548553e-05	0.8	UTY KMT2D PAXIP1 PAGR1	histone methyltransferase complex
CORUM:6340	0.000136445626745	0.4	KMT2D PAXIP1	PITX2-MLL4-ASH2L-RBBP5-PTIP complex
GO:0034708	0.000349949920328	0.8	UTY KMT2D PAXIP1 PAGR1	methyltransferase complex
CORUM:6461	0.000490935356523	0.4	PAGR1 PAXIP1	MLL3 complex
REAC:R-HSA-5619507	0.000595712868223	0.6	PAGR1 PAXIP1 KMT2D	Activation of HOX genes during differentiation
REAC:R-HSA-5617472	0.000595712868223	0.6	PAGR1 PAXIP1 KMT2D	Activation of anterior HOX genes in hindbrain development during early embryogenesis
CORUM:5195	0.000613585186048	0.4	PAGR1 PAXIP1	PTIP-HMT complex
CORUM:3075	0.000899678549321	0.4	KMT2D PAXIP1	UTX-MLL2/3 complex
WP:WP5351	0.00237924603132	0.4	PAGR1 PAXIP1	Kleefstra syndrome
REAC:R-HSA-212165	0.00251144305955	0.6	PAGR1 PAXIP1 KMT2D	Epigenetic regulation of gene expression

Protein 1	Protein 2	Score	ProteomeHD	Evidence
PAGR1	PAXIP1	0.999	0.176	bioplex3_HEK293 bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
PAGR1	KMT2D	0.998	0.106	bioplex3_WMM bioplex3_HCT116 WMM_only
PAGR1	UTY	0.998		bioplex3_WMM bioplex3_HCT116 WMM_only
PAGR1	MTIF3	0.989	0.128	bioplex3_HEK293 bioplex3_WMM WMM_only
PAXIP1	KMT2D	0.975	0.172	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
UTY	PAXIP1	0.91		bioplex3_WMM WMM_only
UTY	KMT2D	0.902		bioplex3_WMM WMM_only
UTY	MTIF3	0.214		bioplex3_WMM WMM_only
MTIF3	KMT2D	0.131	0.05	bioplex3_WMM WMM_only
PAXIP1	MTIF3	0.078	0.176	bioplex3_WMM WMM_only

Genename	Complexes
UTY	huMAP3_00175.1 huMAP3_11602.1 huMAP3_12119.1 huMAP3_12373.1 huMAP3_14057.1 huMAP3_14367.1
MTIF3	huMAP3_02955.1 huMAP3_06832.1 huMAP3_09713.1 huMAP3_10828.1 huMAP3_14057.1 huMAP3_14366.1 huMAP3_14367.1
PAGR1	huMAP3_00175.1 huMAP3_11602.1 huMAP3_12119.1 huMAP3_12373.1 huMAP3_14057.1 huMAP3_14367.1
KMT2D	huMAP3_07585.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_12119.1 huMAP3_12373.1 huMAP3_14057.1 huMAP3_14367.1
PAXIP1	huMAP3_01260.1 huMAP3_11602.1 huMAP3_12119.1 huMAP3_12373.1 huMAP3_14057.1 huMAP3_14367.1