hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14373.1
Complex Portal: CPX-24144
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CCNL1 | Cyclin-L1 (Cyclin-L) | 5 | UniProt NCBI |
| CDK11A | Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2) | 5 | UniProt NCBI |
| SAP30BP | SAP30-binding protein (Transcriptional regulator protein HCNGP) | 5 | UniProt NCBI |
| CCNL2 | Cyclin-L2 (Paneth cell-enhanced expression protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5345 | 0.00578263137464 | 0.5 | CCNL2 CDK11A | 1p36 copy number variation syndrome |
| GO:0000307 | 0.0100599149475 | 0.75 | CCNL2 CCNL1 CDK11A | cyclin-dependent protein kinase holoenzyme complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CDK11A | SAP30BP | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM Malo bioplex3_HCT116 fraction boldt_WMM | ||
| CDK11A | CCNL1 | 1.0 | bioplex3_HEK293 Guru bioplex3_WMM youn_WMM bioplex3_HCT116 fraction | ||
| CCNL1 | SAP30BP | 1.0 | 0.298 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 fraction | |
| CCNL2 | SAP30BP | 0.998 | 0.158 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| CDK11A | CCNL2 | 0.99 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM fraction | |
| CCNL1 | CCNL2 | 0.753 | 0.142 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes