hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14394.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CALCRL | Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor) | 5 | UniProt NCBI |
| PIGL | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (EC 3.5.1.89) (Phosphatidylinositol-glycan biosynthesis class L protein) (PIG-L) | 5 | UniProt NCBI |
| SMIM20 | Small integral membrane protein 20 (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa) (MITRAC7) [Cleaved into: Phoenixin-14 (PNX-14); Phoenixin-20 (PNX-20)] | 5 | UniProt NCBI |
| RAMP1 | Receptor activity-modifying protein 1 (Calcitonin-receptor-like receptor activity-modifying protein 1) (CRLR activity-modifying protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1301 | 5.12628525639e-06 | 0.5 | CALCRL RAMP1 | CRLR-RAMP1 complex |
| CORUM:1300 | 5.12628525639e-06 | 0.5 | CALCRL RAMP1 | CRLR-RAMP1 complex |
| REAC:R-HSA-419812 | 0.000215205765992 | 0.5 | CALCRL RAMP1 | Calcitonin-like ligand receptors |
| WP:WP2197 | 0.000588856887782 | 0.5 | CALCRL RAMP1 | Endothelin pathways |
| GO:0001635 | 0.0028092043205 | 0.5 | CALCRL RAMP1 | calcitonin gene-related peptide receptor activity |
| GO:1990406 | 0.0028092043205 | 0.5 | CALCRL RAMP1 | CGRP receptor complex |
| GO:1990408 | 0.00842684400117 | 0.5 | CALCRL RAMP1 | calcitonin gene-related peptide receptor signaling pathway |
| GO:0097644 | 0.00842684400117 | 0.5 | CALCRL RAMP1 | calcitonin family binding |
| KEGG:04270 | 0.0113396114984 | 0.5 | CALCRL RAMP1 | Vascular smooth muscle contraction |
| WP:WP5224 | 0.0138131669346 | 0.5 | CALCRL RAMP1 | 2q37 copy number variation syndrome |
| GO:1903439 | 0.0168521501606 | 0.5 | CALCRL RAMP1 | calcitonin family receptor complex |
| GO:0097642 | 0.0168521501606 | 0.5 | CALCRL RAMP1 | calcitonin family receptor activity |
| REAC:R-HSA-373080 | 0.0232149434748 | 0.5 | CALCRL RAMP1 | Class B/2 (Secretin family receptors) |
| GO:0097646 | 0.042122686785 | 0.5 | CALCRL RAMP1 | calcitonin family receptor signaling pathway |
| REAC:R-HSA-418555 | 0.0425656343513 | 0.5 | CALCRL RAMP1 | G alpha (s) signalling events |
| CORUM:3140 | 0.049938562206 | 0.25 | CALCRL | CRLR-RAMP2 complex |
| CORUM:3141 | 0.049938562206 | 0.25 | CALCRL | CRLR-RAMP3 complex |
| CORUM:6410 | 0.049938562206 | 0.25 | SMIM20 | MITRAC7-COX1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CALCRL | RAMP1 | 0.989 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SMIM20 | CALCRL | 0.902 | bioplex3_WMM WMM_only | |
| SMIM20 | PIGL | 0.902 | bioplex3_WMM WMM_only | |
| PIGL | CALCRL | 0.902 | bioplex3_WMM WMM_only |
Related Complexes