hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14400.1
Complex Portal: CPX-12741
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARHGAP18 | Rho GTPase-activating protein 18 (MacGAP) (Rho-type GTPase-activating protein 18) | 5 | UniProt NCBI |
| JAK2 | Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2028 | 0.0249718442457 | 0.5 | JAK2 | JAK2-IL12RB2 complex |
| CORUM:5178 | 0.0249718442457 | 0.5 | JAK2 | JAK2-PAFR-TYK2 complex |
| HP:0031386 | 0.0499436884913 | 0.5 | JAK2 | Increased micromegakaryocyte count |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ARHGAP18 | JAK2 | 0.946 | 0.390647058824 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ARHGAP18 | huMAP3_04535.1 huMAP3_07450.1 huMAP3_10043.1 huMAP3_12096.1 huMAP3_12970.1 huMAP3_14400.1 |
| JAK2 | huMAP3_11343.1 huMAP3_12096.1 huMAP3_12970.1 huMAP3_13577.1 huMAP3_14400.1 |