hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14401.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
HDAC6	Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)	5	UniProt NCBI
KCNAB2	Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) (hKvbeta2)	5	UniProt NCBI
KCNA3	Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)	5	UniProt NCBI
KCNAB1	Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1)	5	UniProt NCBI
KCNAB3	Voltage-gated potassium channel subunit beta-3 (EC 1.1.1.-) (K(+) channel subunit beta-3) (Kv-beta-3)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1296072	6.37824653444e-09	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	Voltage gated Potassium channels
REAC:R-HSA-1296071	3.06812697185e-07	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	Potassium Channels
GO:0008076	4.14930734417e-05	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	voltage-gated potassium channel complex
GO:0034705	6.84426164966e-05	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	potassium channel complex
REAC:R-HSA-112316	0.000135335223169	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	Neuronal System
WP:WP702	0.000477678931024	0.6	KCNAB1 KCNAB2 KCNAB3	Metapathway biotransformation Phase I and II
GO:0071805	0.00118663084114	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	potassium ion transmembrane transport
GO:0034703	0.00148410028721	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	cation channel complex
GO:0006813	0.00157850838896	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	potassium ion transport
GO:0004033	0.00194127795747	0.6	KCNAB1 KCNAB2 KCNAB3	aldo-keto reductase (NADP) activity
GO:0034702	0.00407551040215	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	monoatomic ion channel complex
GO:0015459	0.00522817157061	0.6	KCNAB1 KCNAB2 KCNAB3	potassium channel regulator activity
GO:1902495	0.0187071120569	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	transmembrane transporter complex
GO:1901379	0.0224016609185	0.6	KCNAB1 KCNAB2 KCNAB3	regulation of potassium ion transmembrane transport
GO:1990351	0.025656507175	0.8	KCNA3 KCNAB3 KCNAB2 KCNAB1	transporter complex
GO:0043266	0.0294915925302	0.6	KCNAB1 KCNAB2 KCNAB3	regulation of potassium ion transport
GO:0030424	0.0334179111257	0.8	KCNA3 KCNAB1 HDAC6 KCNAB2	axon
HP:0000878	0.0497672375822	0.4	HDAC6 KCNAB2	11 pairs of ribs
CORUM:7389	0.0498708842806	0.2	KCNAB2	Potassium channel complex (KCNA1, KCNA2, KCNAB2)

Protein 1	Protein 2	Score	ProteomeHD	Evidence
KCNAB2	KCNAB3	0.998	0.132	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
HDAC6	KCNAB3	0.994	0.07	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
KCNAB1	KCNAB2	0.988	0.63	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
KCNAB2	KCNA3	0.944		bioplex_WMM bioplex3_WMM WMM_only
KCNAB2	HDAC6	0.91	0.052	bioplex_WMM bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
HDAC6	huMAP3_06461.1 huMAP3_09251.1 huMAP3_10381.1 huMAP3_12248.1 huMAP3_14401.1
KCNAB2	huMAP3_02341.1 huMAP3_04930.1 huMAP3_07655.1 huMAP3_09448.1 huMAP3_10381.1 huMAP3_13061.1 huMAP3_14401.1
KCNA3	huMAP3_03607.1 huMAP3_06902.1 huMAP3_08542.1 huMAP3_08781.1 huMAP3_09093.1 huMAP3_09697.1 huMAP3_10584.1 huMAP3_12212.1 huMAP3_13061.1 huMAP3_14401.1
KCNAB1	huMAP3_02341.1 huMAP3_04930.1 huMAP3_07655.1 huMAP3_09448.1 huMAP3_10381.1 huMAP3_13061.1 huMAP3_14401.1
KCNAB3	huMAP3_07655.1 huMAP3_09251.1 huMAP3_10381.1 huMAP3_11194.1 huMAP3_13061.1 huMAP3_14401.1 huMAP3_15127.1