hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14430.1
Complex Portal: CPX-23279
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ERI3 | ERI1 exoribonuclease 3 (EC 3.1.-.-) (Prion interactor 1) (Prion protein-interacting protein) | 4 | UniProt NCBI |
| VWC2L | von Willebrand factor C domain-containing protein 2-like (VWC2-like protein) (Brorin-like) | 5 | UniProt NCBI |
| NR1I3 | Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67) | 5 | UniProt NCBI |
| NCOA1 | Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1) | 5 | UniProt NCBI |
| STAT6 | Signal transducer and activator of transcription 6 (IL-4 Stat) | 5 | UniProt NCBI |
| SPX | Spexin (NPQ) (Neuropeptide Q) (Spexin hormone) [Cleaved into: Spexin-1; Spexin-2 (NPQ 53-70)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2875 | 0.00276984458443 | 0.333333333333 | NR1I3 NCOA1 | Constitutive androstane receptor pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ERI3 | VWC2L | 0.98 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| STAT6 | NCOA1 | 0.976 | 0.114 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ERI3 | SPX | 0.967 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NCOA1 | NR1I3 | 0.96 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| NCOA1 | VWC2L | 0.939 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NCOA1 | SPX | 0.873 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NCOA1 | ERI3 | 0.081 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes