hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14450.1
Complex Portal: CPX-15871
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MTFMT | Methionyl-tRNA formyltransferase, mitochondrial (MtFMT) (EC 2.1.2.9) | 5 | UniProt NCBI |
| MRPL12 | Large ribosomal subunit protein bL12m (39S ribosomal protein L12, mitochondrial) (L12mt) (MRP-L12) (5c5-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0008347 | 0.00507502240382 | 1.0 | MTFMT MRPL12 | Decreased activity of mitochondrial complex IV |
| REAC:R-HSA-5368286 | 0.00639247771471 | 1.0 | MTFMT MRPL12 | Mitochondrial translation initiation |
| REAC:R-HSA-5368287 | 0.00731008277561 | 1.0 | MTFMT MRPL12 | Mitochondrial translation |
| HP:0011923 | 0.0133830220427 | 1.0 | MTFMT MRPL12 | Decreased activity of mitochondrial complex I |
| HP:0008972 | 0.0277776310426 | 1.0 | MTFMT MRPL12 | Decreased activity of mitochondrial respiratory chain |
| HP:0011922 | 0.0295479082178 | 1.0 | MTFMT MRPL12 | Abnormal activity of mitochondrial respiratory chain |
| KEGG:00670 | 0.0356198329076 | 0.5 | MTFMT | One carbon pool by folate |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MRPL12 | MTFMT | 0.962 | 0.37 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes