hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14453.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
CCSER1	Serine-rich coiled-coil domain-containing protein 1 (Coiled-coil serine-rich protein 1)	3	UniProt NCBI
NDE1	Nuclear distribution protein nudE homolog 1 (NudE)	5	UniProt NCBI
FAM124A	Protein FAM124A	5	UniProt NCBI
SHTN1	Shootin-1 (Shootin1)	5	UniProt NCBI
PAFAH1B3	Platelet-activating factor acetylhydrolase IB subunit alpha1 (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma)	5	UniProt NCBI
CGNL1	Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin)	5	UniProt NCBI
NDEL1	Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)	5	UniProt NCBI
PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)	5	UniProt NCBI
CCSER2	Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog)	4	UniProt NCBI
PAFAH1B2	Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta)	5	UniProt NCBI
DIXDC1	Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP5409	3.79807015955e-09	0.363636363636	PAFAH1B2 PAFAH1B3 NDEL1 PAFAH1B1	PAFAH1B1 copy number variation
GO:0008247	1.58598067776e-05	0.272727272727	PAFAH1B3 PAFAH1B2 PAFAH1B1	1-alkyl-2-acetylglycerophosphocholine esterase complex
KEGG:00565	0.000123874719226	0.272727272727	PAFAH1B3 PAFAH1B2 PAFAH1B1	Ether lipid metabolism
REAC:R-HSA-6811436	0.00157982189593	0.272727272727	PAFAH1B3 PAFAH1B2 PAFAH1B1	COPI-independent Golgi-to-ER retrograde traffic
REAC:R-HSA-141444	0.00994872303174	0.272727272727	NDE1 NDEL1 PAFAH1B1	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
REAC:R-HSA-141424	0.00994872303174	0.272727272727	NDE1 NDEL1 PAFAH1B1	Amplification of signal from the kinetochores
WP:WP5376	0.0101391714355	0.181818181818	PAFAH1B1 NDEL1	17p13 3 YWHAE copy number variation
REAC:R-HSA-69618	0.0160674755621	0.272727272727	NDE1 NDEL1 PAFAH1B1	Mitotic Spindle Checkpoint
REAC:R-HSA-9648025	0.0183890488448	0.272727272727	NDE1 NDEL1 PAFAH1B1	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-2500257	0.0225435374124	0.272727272727	NDE1 NDEL1 PAFAH1B1	Resolution of Sister Chromatid Cohesion
REAC:R-HSA-8856688	0.0254282217101	0.272727272727	PAFAH1B3 PAFAH1B2 PAFAH1B1	Golgi-to-ER retrograde transport
REAC:R-HSA-5663220	0.0291963444427	0.272727272727	NDE1 NDEL1 PAFAH1B1	RHO GTPases Activate Formins
GO:0030010	0.0328160426431	0.363636363636	NDE1 PAFAH1B1 SHTN1 NDEL1	establishment of cell polarity

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
PAFAH1B3	PAFAH1B2	1.0	0.406	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 boldt_WMM
NDEL1	DIXDC1	1.0	0.094	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116
CCSER1	NDEL1	1.0		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
NDEL1	CCSER2	1.0	0.122	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM
NDE1	NDEL1	0.999		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM
CCSER1	NDE1	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
PAFAH1B1	PAFAH1B3	0.999	0.048	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 fraction boldt_WMM
PAFAH1B1	PAFAH1B2	0.997	0.52	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 fraction boldt_WMM
NDEL1	PAFAH1B1	0.996	0.266	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 gupta_WMM boldt_WMM
NDE1	CCSER2	0.994		hein_WMM bioplex_WMM bioplex3_WMM hein () gupta_WMM
NDE1	DIXDC1	0.991		hein_WMM bioplex_WMM bioplex3_WMM WMM_only
NDE1	PAFAH1B1	0.985		hein_WMM bioplex_WMM bioplex3_WMM boldt hein () gupta_WMM boldt_WMM
CCSER2	PAFAH1B1	0.982	0.0977	hein_WMM bioplex_WMM bioplex3_WMM hein () gupta_WMM
DIXDC1	PAFAH1B1	0.961	0.1	hein_WMM bioplex_WMM bioplex3_WMM hein ()
PAFAH1B1	SHTN1	0.951	0.086	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
DIXDC1	FAM124A	0.94	0.048	bioplex3_HEK293 bioplex3_WMM WMM_only
NDEL1	SHTN1	0.925	0.102	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
CCSER2	DIXDC1	0.902	0.108	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
CCSER1	PAFAH1B1	0.893		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
CCSER1	CCSER2	0.885		bioplex_WMM bioplex3_WMM WMM_only
NDE1	CGNL1	0.869		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
CCSER1	DIXDC1	0.735		bioplex_WMM bioplex3_WMM WMM_only
NDE1	SHTN1	0.497		hein_WMM bioplex_WMM bioplex3_WMM WMM_only
NDEL1	PAFAH1B3	0.354	0.102	hein_WMM WMM_only boldt_WMM
CCSER2	CGNL1	0.331	0.058	bioplex3_WMM youn_WMM WMM_only
DIXDC1	SHTN1	0.22	0.098	bioplex_WMM bioplex3_WMM WMM_only
CCSER1	SHTN1	0.201		bioplex_WMM bioplex3_WMM WMM_only
CCSER2	PAFAH1B3	0.192	0.048	hein_WMM WMM_only
CCSER2	PAFAH1B2	0.192	0.076	hein_WMM WMM_only
NDE1	FAM124A	0.182		bioplex3_HEK293 bioplex3_WMM WMM_only
CCSER2	SHTN1	0.17	0.1	bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM
DIXDC1	PAFAH1B3	0.063	0.06	hein_WMM WMM_only
DIXDC1	PAFAH1B2	0.063	0.04	hein_WMM WMM_only
NDEL1	PAFAH1B2	0.062	0.312	hein_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
NDE1	PAFAH1B2	0.056		hein_WMM boldt boldt_WMM WMM_only
NDEL1	FAM124A	0.043	0.156	bioplex3_HEK293 WMM_only
NDE1	PAFAH1B3	0.043		hein_WMM WMM_only boldt_WMM
NDEL1	CGNL1	0.032	0.084	bioplex3_WMM gupta_WMM WMM_only
PAFAH1B2	SHTN1	0.008	0.076	gupta_WMM WMM_only
SHTN1	CGNL1	0.006	0.05	youn_WMM WMM_only
PAFAH1B3	SHTN1	0.005	0.084	bioplex3_WMM gupta_WMM WMM_only

Related Complexes

Genename	Complexes
CCSER1	huMAP3_01204.1 huMAP3_01919.1 huMAP3_10973.1 huMAP3_11571.1 huMAP3_12060.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1
NDE1	huMAP3_01204.1 huMAP3_08459.1 huMAP3_09108.1 huMAP3_10973.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1
FAM124A	huMAP3_01821.1 huMAP3_04175.1 huMAP3_05795.1 huMAP3_11571.1 huMAP3_11667.1 huMAP3_12060.1 huMAP3_12687.1 huMAP3_13495.1 huMAP3_13624.1 huMAP3_13860.1 huMAP3_14453.1 huMAP3_14642.1 huMAP3_15025.1
SHTN1	huMAP3_04943.1 huMAP3_07887.1 huMAP3_09314.1 huMAP3_09646.1 huMAP3_10738.1 huMAP3_11571.1 huMAP3_11880.1 huMAP3_13680.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1
PAFAH1B3	huMAP3_01909.1 huMAP3_10973.1 huMAP3_11571.1 huMAP3_12060.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1
CGNL1	huMAP3_13860.1 huMAP3_14453.1
NDEL1	huMAP3_01204.1 huMAP3_08459.1 huMAP3_09108.1 huMAP3_10973.1 huMAP3_11571.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1
PAFAH1B1	huMAP3_01909.1 huMAP3_02284.1 huMAP3_06898.1 huMAP3_10973.1 huMAP3_11571.1 huMAP3_12060.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1
CCSER2	huMAP3_01204.1 huMAP3_01883.1 huMAP3_06898.1 huMAP3_09108.1 huMAP3_09374.1 huMAP3_10079.1 huMAP3_10973.1 huMAP3_11571.1 huMAP3_12060.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1
PAFAH1B2	huMAP3_01909.1 huMAP3_02284.1 huMAP3_06898.1 huMAP3_10973.1 huMAP3_11571.1 huMAP3_12060.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1
DIXDC1	huMAP3_01204.1 huMAP3_07988.1 huMAP3_08459.1 huMAP3_09108.1 huMAP3_10973.1 huMAP3_11571.1 huMAP3_11667.1 huMAP3_12060.1 huMAP3_12360.1 huMAP3_13624.1 huMAP3_13860.1 huMAP3_14428.1 huMAP3_14453.1 huMAP3_15025.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_14453.1