hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14461.1
Complex Portal: CPX-14926
Confidence: Medium  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BMX | Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) | 5 | UniProt   NCBI |
| CASP7 | Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] | 5 | UniProt   NCBI |
| CC2D1B | Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   REAC:R-HSA-111465 | 0.00405087414568 | 0.666666666667 | BMX CASP7 | Apoptotic cleavage of cellular proteins |
|   REAC:R-HSA-75153 | 0.00800131218049 | 0.666666666667 | BMX CASP7 | Apoptotic execution phase |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  BMX |  CC2D1B | 0.952 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  CASP7 |  CC2D1B | 0.943 | 0.082           |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes