hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14473.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
PRRT4 | Proline-rich transmembrane protein 4 | 3 | UniProt   NCBI |
PITPNM1 | Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) | 5 | UniProt   NCBI |
OSBP | Oxysterol-binding protein 1 | 5 | UniProt   NCBI |
PITPNM2 | Membrane-associated phosphatidylinositol transfer protein 2 (Phosphatidylinositol transfer protein, membrane-associated 2) (PITPnm 2) (Pyk2 N-terminal domain-interacting receptor 3) (NIR-3) | 5 | UniProt   NCBI |
OSBP2 | Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (ORP-4) (OSBP-related protein 4) | 5 | UniProt   NCBI |
USP20 | Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (VHL-interacting deubiquitinating enzyme 2) (hVDU2) | 5 | UniProt   NCBI |
OSBPL9 | Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9) | 5 | UniProt   NCBI |
SLC22A15 | Solute carrier family 22 member 15 (Fly-like putative transporter 1) (Flipt 1) | 5 | UniProt   NCBI |
OSBPL10 | Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10) | 5 | UniProt   NCBI |
PITPNM3 | Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1) | 5 | UniProt   NCBI |
VAPA | Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33) | 5 | UniProt   NCBI |
RAB3GAP1 | Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP) | 5 | UniProt   NCBI |
USP33 | Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.4.19.12) (Deubiquitinating enzyme 33) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (VHL-interacting deubiquitinating enzyme 1) (hVDU1) | 5 | UniProt   NCBI |
RASSF3 | Ras association domain-containing protein 3 | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  GO:0005319 | 2.54602877408e-07 | 0.5 | OSBPL9 PITPNM3 OSBP2 PITPNM2 PITPNM1 OSBP OSBPL10 | lipid transporter activity |
  REAC:R-HSA-1483226 | 1.96338187373e-06 | 0.214285714286 | PITPNM1 PITPNM2 PITPNM3 | Synthesis of PI |
  REAC:R-HSA-556833 | 0.000162707251422 | 0.5 | OSBPL9 VAPA PITPNM3 PITPNM2 PITPNM1 OSBP OSBPL10 | Metabolism of lipids |
  GO:0015248 | 0.000389049485032 | 0.285714285714 | OSBPL10 OSBP OSBP2 OSBPL9 | sterol transporter activity |
  REAC:R-HSA-1483206 | 0.000669210499299 | 0.285714285714 | PITPNM3 PITPNM1 PITPNM2 OSBPL10 | Glycerophospholipid biosynthesis |
  GO:0008526 | 0.00195378579303 | 0.214285714286 | PITPNM1 PITPNM2 PITPNM3 | phosphatidylinositol transfer activity |
  GO:0120013 | 0.00212524869335 | 0.285714285714 | PITPNM3 PITPNM1 PITPNM2 OSBP | lipid transfer activity |
  GO:0005548 | 0.00288735797113 | 0.285714285714 | PITPNM3 PITPNM1 PITPNM2 OSBPL10 | phospholipid transporter activity |
  GO:0032934 | 0.00458852246317 | 0.285714285714 | OSBPL10 OSBP OSBP2 OSBPL9 | sterol binding |
  REAC:R-HSA-1483257 | 0.00520095264123 | 0.285714285714 | PITPNM3 PITPNM1 PITPNM2 OSBPL10 | Phospholipid metabolism |
  GO:0005215 | 0.00681182491667 | 0.571428571429 | OSBPL9 PITPNM3 OSBP2 PITPNM2 PITPNM1 OSBP SLC22A15 OSBPL10 | transporter activity |
  GO:0006644 | 0.00716020683791 | 0.428571428571 | VAPA PITPNM3 PITPNM2 PITPNM1 OSBP OSBPL10 | phospholipid metabolic process |
  GO:0005496 | 0.0161936013808 | 0.285714285714 | OSBPL10 OSBP OSBP2 OSBPL9 | steroid binding |
  GO:0008654 | 0.0320658347688 | 0.357142857143 | PITPNM3 PITPNM1 VAPA PITPNM2 OSBP | phospholipid biosynthetic process |
  GO:0120014 | 0.0395048083263 | 0.214285714286 | PITPNM1 PITPNM2 PITPNM3 | phospholipid transfer activity |
  REAC:R-HSA-192105 | 0.049745617661 | 0.142857142857 | OSBP OSBPL9 | Synthesis of bile acids and bile salts |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD |
---|---|---|---|
 VAPA |  OSBPL9 | 0.998 | 0.106           |
 VAPA |  OSBP2 | 0.997 | 0.142           |
 VAPA |  OSBPL10 | 0.994 | 0.032           |
 VAPA |  OSBP | 0.992 | 0.126           |
 VAPA |  PITPNM3 | 0.992 |            |
 USP20 |  USP33 | 0.988 | 0.124           |
 VAPA |  PITPNM1 | 0.983 | 0.11           |
 SLC22A15 |  VAPA | 0.957 |            |
 VAPA |  PITPNM2 | 0.944 | 0.104363095238           |
 OSBP |  OSBP2 | 0.94 | 0.122           |
 OSBP |  USP33 | 0.938 | 0.182           |
 SLC22A15 |  RASSF3 | 0.904 |            |
 PITPNM3 |  PRRT4 | 0.902 |            |
 PRRT4 |  RASSF3 | 0.902 |            |
 SLC22A15 |  PITPNM1 | 0.902 |            |
 SLC22A15 |  PRRT4 | 0.902 |            |
 SLC22A15 |  PITPNM2 | 0.902 |            |
 PRRT4 |  PITPNM2 | 0.902 |            |
 PITPNM1 |  PRRT4 | 0.902 |            |
 PITPNM1 |  RASSF3 | 0.902 | 0.088           |
 OSBP2 |  PRRT4 | 0.902 |            |
 PITPNM2 |  RASSF3 | 0.902 | 0.072           |
 PITPNM1 |  OSBP2 | 0.897 | 0.108           |
 OSBP2 |  PITPNM2 | 0.897 | 0.082           |
 PRRT4 |  OSBPL9 | 0.892 |            |
 VAPA |  USP33 | 0.89 | 0.158           |
 PITPNM1 |  PITPNM2 | 0.881 | 0.086           |
 PITPNM1 |  OSBPL10 | 0.88 | 0.064           |
 PITPNM2 |  OSBPL10 | 0.88 | 0.036           |
 OSBP2 |  OSBPL9 | 0.862 | 0.138           |
 USP20 |  RAB3GAP1 | 0.862 | 0.156           |
 OSBP2 |  OSBPL10 | 0.849 | 0.09           |
 PITPNM1 |  PITPNM3 | 0.843 |            |
 PITPNM3 |  PITPNM2 | 0.843 |            |
 USP33 |  RAB3GAP1 | 0.826 | 0.112           |
 OSBP |  RAB3GAP1 | 0.821 | 0.376           |
 OSBP |  OSBPL9 | 0.821 | 0.104           |
 PITPNM3 |  USP33 | 0.818 |            |
 VAPA |  RAB3GAP1 | 0.792 | 0.048           |
 PITPNM3 |  OSBP2 | 0.778 |            |
 OSBPL9 |  USP33 | 0.778 | 0.296           |
 PITPNM1 |  OSBPL9 | 0.772 | 0.056           |
 PITPNM2 |  OSBPL9 | 0.772 | 0.062           |
 PRRT4 |  RAB3GAP1 | 0.754 |            |
 OSBP |  OSBPL10 | 0.751 | 0.076           |
 PITPNM1 |  USP20 | 0.739 | 0.086           |
 PITPNM2 |  USP20 | 0.739 | 0.066           |
 PITPNM1 |  RAB3GAP1 | 0.739 | 0.062           |
 PITPNM2 |  RAB3GAP1 | 0.739 | 0.04           |
 OSBPL9 |  RAB3GAP1 | 0.733 | 0.136           |
 OSBP |  PITPNM2 | 0.731 | 0.088           |
 PITPNM1 |  OSBP | 0.731 | 0.102           |
 PRRT4 |  USP20 | 0.73 |            |
 PITPNM3 |  RASSF3 | 0.722 |            |
 SLC22A15 |  OSBP2 | 0.722 |            |
 SLC22A15 |  PITPNM3 | 0.717 |            |
 SLC22A15 |  USP20 | 0.715 |            |
 OSBPL9 |  RASSF3 | 0.715 | 0.044           |
 SLC22A15 |  RAB3GAP1 | 0.715 |            |
 PITPNM1 |  USP33 | 0.699 | 0.054           |
 PITPNM2 |  USP33 | 0.699 | 0.064           |
 USP20 |  OSBPL9 | 0.698 | 0.322           |
 SLC22A15 |  OSBPL9 | 0.697 |            |
 OSBP |  PRRT4 | 0.696 |            |
 VAPA |  USP20 | 0.693 | 0.228           |
 OSBP |  PITPNM3 | 0.677 |            |
 PRRT4 |  OSBPL10 | 0.676 |            |
 PRRT4 |  USP33 | 0.675 |            |
 RAB3GAP1 |  RASSF3 | 0.675 | 0.044           |
 USP20 |  RASSF3 | 0.675 | 0.086           |
 SLC22A15 |  USP33 | 0.663 |            |
 PITPNM3 |  RAB3GAP1 | 0.652 |            |
 OSBP2 |  RASSF3 | 0.647 | 0.066           |
 SLC22A15 |  OSBPL10 | 0.633 |            |
 OSBPL9 |  OSBPL10 | 0.624 | 0.804           |
 PITPNM3 |  OSBPL10 | 0.617 |            |
 OSBP2 |  USP33 | 0.614 | 0.088           |
 PITPNM3 |  USP20 | 0.611 |            |
 PITPNM3 |  OSBPL9 | 0.611 |            |
 USP33 |  RASSF3 | 0.552 | 0.09           |
 OSBP2 |  RAB3GAP1 | 0.548 | 0.068           |
 OSBP2 |  USP20 | 0.548 | 0.112           |
 RAB3GAP1 |  OSBPL10 | 0.539 | 0.058           |
 USP20 |  OSBPL10 | 0.539 | 0.106           |
 USP33 |  OSBPL10 | 0.475 | 0.122           |
 OSBP |  USP20 | 0.441 | 0.282           |
 RASSF3 |  OSBPL10 | 0.401 | 0.032           |
 OSBP |  RASSF3 | 0.335 | 0.048           |
 SLC22A15 |  OSBP | 0.323 |            |
 VAPA |  PRRT4 | 0.188 |            |
 VAPA |  RASSF3 | 0.099 | 0.082           |
Related Complexes