hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14475.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAHD2A | Fumarylacetoacetate hydrolase domain-containing protein 2A (EC 3.-.-.-) | 3 | UniProt NCBI |
| GLRX5 | Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5) | 5 | UniProt NCBI |
| FAHD2B | Fumarylacetoacetate hydrolase domain-containing protein 2B (EC 3.-.-.-) | 2 | UniProt NCBI |
| BOLA3 | BolA-like protein 3 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0002928 | 0.00150383256857 | 0.5 | GLRX5 BOLA3 | Decreased activity of the pyruvate dehydrogenase complex |
| HP:0002154 | 0.00400802433742 | 0.5 | GLRX5 BOLA3 | Hyperglycinemia |
| HP:0010895 | 0.0051092979876 | 0.5 | GLRX5 BOLA3 | Abnormal circulating glycine concentration |
| HP:0010894 | 0.00701084122037 | 0.5 | GLRX5 BOLA3 | Abnormal circulating serine family amino acid concentration |
| GO:0106035 | 0.0280843539964 | 0.5 | GLRX5 BOLA3 | protein maturation by [4Fe-4S] cluster transfer |
| TF:M05423 | 0.042122686785 | 0.5 | FAHD2A FAHD2B | Factor: RREB-1; motif: NGTGGCRGGTAAACGC |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FAHD2A | FAHD2B | 0.999 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| FAHD2A | BOLA3 | 0.992 | 0.052 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GLRX5 | BOLA3 | 0.946 | 0.134 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| FAHD2B | BOLA3 | 0.909 | 0.096 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| FAHD2A | GLRX5 | 0.009 | 0.022 | bioplex_WMM WMM_only |
Related Complexes