hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14480.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MFN2 | Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2) | 5 | UniProt NCBI |
| MFN1 | Mitofusin-1 (EC 3.6.5.-) (Fzo homolog) (Transmembrane GTPase MFN1) | 5 | UniProt NCBI |
| UQCC6 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (Protein BRAWNIN) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9013419 | 0.000143154936711 | 0.666666666667 | MFN2 MFN1 | RHOT2 GTPase cycle |
| REAC:R-HSA-9715370 | 0.000190864539041 | 0.666666666667 | MFN2 MFN1 | Miro GTPase Cycle |
| REAC:R-HSA-5205685 | 0.00143063482691 | 0.666666666667 | MFN2 MFN1 | PINK1-PRKN Mediated Mitophagy |
| REAC:R-HSA-5205647 | 0.00221357222266 | 0.666666666667 | MFN2 MFN1 | Mitophagy |
| KEGG:04137 | 0.00361241039138 | 0.666666666667 | MFN2 MFN1 | Mitophagy - animal |
| KEGG:04621 | 0.00802719593767 | 0.666666666667 | MFN2 MFN1 | NOD-like receptor signaling pathway |
| REAC:R-HSA-9663891 | 0.0188582038017 | 0.666666666667 | MFN2 MFN1 | Selective autophagy |
| KEGG:05012 | 0.0212975456297 | 0.666666666667 | MFN2 MFN1 | Parkinson disease |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MFN1 | MFN2 | 0.994 | 0.286 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| UQCC6 | MFN2 | 0.877 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes