hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14495.1
Complex Portal: CPX-12290
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PPM1K | Protein phosphatase Mn(2+)-dependent 1K (EC 3.1.3.16) (Branched-chain alpha-ketoacid dehydrogenase phosphatase) (BCKDH) (BDP) (EC 3.1.3.52) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C family member) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) ([3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase, mitochondrial) | 5 | UniProt NCBI |
| CD1A | T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a) | 5 | UniProt NCBI |
| BCKDHB | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010892 | 0.000695688281083 | 0.666666666667 | PPM1K BCKDHB | Abnormal circulating branched chain amino acid concentration |
| REAC:R-HSA-70895 | 0.00143063482691 | 0.666666666667 | PPM1K BCKDHB | Branched-chain amino acid catabolism |
| HP:0033107 | 0.0493566712329 | 0.666666666667 | PPM1K BCKDHB | Abnormal circulating proteinogenic amino acid concentration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BCKDHB | PPM1K | 0.844 |
structurally_consistent (P12694)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CD1A | BCKDHB | 0.811 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes