hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14516.1
Complex Portal: CPX-14644
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAP10 | Microtubule-associated protein 10 (Microtubule regulator of 120 KDa) | 5 | UniProt NCBI |
| CEP76 | Centrosomal protein of 76 kDa (Cep76) | 5 | UniProt NCBI |
| RPS6KB2 | Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta) | 5 | UniProt NCBI |
| SH2B3 | SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) | 5 | UniProt NCBI |
| ZFAND1 | AN1-type zinc finger protein 1 (Zinc finger AN1-type-containing protein 1) | 5 | UniProt NCBI |
| FHL5 | Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP-responsive element modulator in testis) (Activator of CREM in testis) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0180053 | 0.01045837038 | 0.833333333333 | CEP76 SH2B3 MAP10 ZFAND1 RPS6KB2 | epididymis; glandular cells[High] |
| CORUM:3185 | 0.0499436884912 | 0.166666666667 | FHL5 | ACT homodimer complex |
| CORUM:3191 | 0.0499436884912 | 0.166666666667 | FHL5 | ACT-CREB complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CEP76 | RPS6KB2 | 0.998 | 0.11 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CEP76 | MAP10 | 0.988 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ZFAND1 | CEP76 | 0.904 | 0.118 | bioplex3_WMM WMM_only | |
| CEP76 | SH2B3 | 0.904 | 0.17 | bioplex3_WMM WMM_only | |
| CEP76 | FHL5 | 0.851 | bioplex3_HEK293 bioplex () |
Related Complexes