hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14548.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OAZ3 | Ornithine decarboxylase antizyme 3 (AZ3) (ODC-Az 3) | 5 | UniProt NCBI |
| OAZ1 | Ornithine decarboxylase antizyme 1 (AZ1) (ODC-Az) | 5 | UniProt NCBI |
| RGN | Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30) | 5 | UniProt NCBI |
| AZIN1 | Antizyme inhibitor 1 (AZI) (AZI1) (Ornithine decarboxylase antizyme inhibitor) | 5 | UniProt NCBI |
| ODC1 | Ornithine decarboxylase (ODC) (EC 4.1.1.17) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0042979 | 3.84440695359e-06 | 0.75 | OAZ1 OAZ3 AZIN1 | ornithine decarboxylase regulator activity |
| REAC:R-HSA-350562 | 2.7436612495e-05 | 0.75 | OAZ1 OAZ3 AZIN1 | Regulation of ornithine decarboxylase (ODC) |
| REAC:R-HSA-351202 | 3.87912301308e-05 | 0.75 | OAZ1 OAZ3 AZIN1 | Metabolism of polyamines |
| REAC:R-HSA-71291 | 0.007608748274 | 0.75 | OAZ1 OAZ3 AZIN1 | Metabolism of amino acids and derivatives |
| GO:0008073 | 0.00842684400117 | 0.5 | OAZ1 OAZ3 | ornithine decarboxylase inhibitor activity |
| GO:1902267 | 0.00842684400117 | 0.5 | AZIN1 OAZ3 | regulation of polyamine transmembrane transport |
| GO:1902047 | 0.042122686785 | 0.5 | AZIN1 OAZ3 | polyamine transmembrane transport |
| CORUM:6642 | 0.049938562206 | 0.25 | OAZ1 | ODC-OAZ1-CCND1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AZIN1 | OAZ3 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| OAZ3 | ODC1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| AZIN1 | OAZ1 | 0.999 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | |
| OAZ3 | RGN | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| AZIN1 | ODC1 | 0.906 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| OAZ1 | ODC1 | 0.828 | hein_WMM hein () | |
| ODC1 | RGN | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| AZIN1 | RGN | 0.502 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes