hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14549.1
Complex Portal: CPX-18751
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADA | Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase) | 5 | UniProt NCBI |
| PTRHD1 | Putative peptidyl-tRNA hydrolase PTRHD1 (EC 3.1.1.29) (Peptidyl-tRNA hydrolase domain-containing protein 1) | 2 | UniProt NCBI |
| MPI | Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9734735 | 0.0498224659464 | 0.333333333333 | ADA | Defective ADA disrupts (deoxy)adenosine deamination |
| REAC:R-HSA-4043916 | 0.0498224659464 | 0.333333333333 | MPI | Defective MPI causes MPI-CDG |
| CORUM:7308 | 0.0499402709677 | 0.333333333333 | ADA | ADA-DPP4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MPI | ADA | 0.946 | 0.04 | bioplex3_WMM bioplex3_HCT116 fraction | |
| MPI | PTRHD1 | 0.841 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes