hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14558.1
Complex Portal: CPX-10578
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BOLA2 | BolA-like protein 2 | 5 | UniProt NCBI |
| GLRX3 | Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2) | 5 | UniProt NCBI |
| NDOR1 | NADPH-dependent diflavin oxidoreductase 1 (EC 1.18.1.-) (NADPH-dependent FMN and FAD-containing oxidoreductase) (Novel reductase 1) | 5 | UniProt NCBI |
| RGS19 | Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP) | 5 | UniProt NCBI |
| CIAPIN1 | Anamorsin (Cytokine-induced apoptosis inhibitor 1) (Fe-S cluster assembly protein DRE2 homolog) | 5 | UniProt NCBI |
| RGS20 | Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1) | 5 | UniProt NCBI |
| MPLKIP | M-phase-specific PLK1-interacting protein (TTD non-photosensitive 1 protein) | 5 | UniProt NCBI |
| BOLA1 | BolA-like protein 1 (hBolA) | 5 | UniProt NCBI |
| NARF | Nuclear prelamin A recognition factor (Iron-only hydrogenase-like protein 2) (IOP2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016226 | 3.75147389958e-05 | 0.5 | BOLA1 CIAPIN1 GLRX3 NDOR1 | iron-sulfur cluster assembly |
| GO:0031163 | 3.75147389958e-05 | 0.5 | BOLA1 CIAPIN1 GLRX3 NDOR1 | metallo-sulfur cluster assembly |
| REAC:R-HSA-2564830 | 0.00433819320746 | 0.25 | NDOR1 CIAPIN1 | Cytosolic iron-sulfur cluster assembly |
| REAC:R-HSA-418597 | 0.0328938418336 | 0.25 | RGS20 RGS19 | G alpha (z) signalling events |
| CORUM:6211 | 0.0499436884912 | 0.125 | RGS20 | RSG20-MT1-MT2 complex |
| CORUM:6958 | 0.0499436884912 | 0.125 | GLRX3 | BOLA2-GLRX3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GLRX3 | CIAPIN1 | 1.0 | 0.3 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| BOLA1 | GLRX3 | 1.0 | 0.114 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RGS20 | GLRX3 | 0.999 | 0.09 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NARF | RGS20 | 0.999 | 0.124 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NDOR1 | CIAPIN1 | 0.998 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RGS20 | CIAPIN1 | 0.998 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| BOLA1 | CIAPIN1 | 0.996 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| BOLA2 | CIAPIN1 | 0.993 | 0.098 |
structurally_consistent (O76003)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RGS19 | RGS20 | 0.993 | 0.17 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GLRX3 | BOLA2 | 0.987 | 0.22 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RGS20 | BOLA2 | 0.985 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GLRX3 | NDOR1 | 0.983 | 0.08 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM fraction | |
| MPLKIP | NDOR1 | 0.929 | 0.09 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| NARF | BOLA2 | 0.917 | 0.118 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| BOLA1 | NDOR1 | 0.878 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only | |
| BOLA1 | RGS20 | 0.873 | 0.11 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| BOLA1 | BOLA2 | 0.868 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| NARF | GLRX3 | 0.807 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only | |
| NDOR1 | BOLA2 | 0.744 | 0.116 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| NARF | RGS19 | 0.627 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only | |
| NARF | CIAPIN1 | 0.563 | 0.11 | bioplex_WMM bioplex3_WMM WMM_only | |
| RGS19 | CIAPIN1 | 0.553 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| RGS19 | GLRX3 | 0.545 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only | |
| RGS19 | BOLA2 | 0.455 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| BOLA1 | NARF | 0.143 | 0.126 | bioplex_WMM bioplex3_WMM WMM_only | |
| MPLKIP | GLRX3 | 0.086 | 0.092 | bioplex3_WMM WMM_only | |
| BOLA1 | RGS19 | 0.058 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only | |
| MPLKIP | CIAPIN1 | 0.047 | 0.084 | bioplex3_WMM WMM_only | |
| NARF | MPLKIP | 0.042 | 0.118 | bioplex3_WMM WMM_only | |
| MPLKIP | BOLA2 | 0.016 | 0.098 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes