hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14562.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DGUOK | Deoxyguanosine kinase, mitochondrial (EC 2.7.1.113) (Deoxyadenosine kinase, mitochondrial) (EC 2.7.1.76) | 5 | UniProt NCBI |
| DCK | Deoxycytidine kinase (dCK) (EC 2.7.1.74) (Deoxyadenosine kinase) (EC 2.7.1.76) (Deoxyguanosine kinase) (EC 2.7.1.113) | 5 | UniProt NCBI |
| PLEKHG2 | Pleckstrin homology domain-containing family G member 2 (PH domain-containing family G member 2) | 5 | UniProt NCBI |
| ERC2 | ERC protein 2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-74217 | 0.000563428413222 | 0.5 | DCK DGUOK | Purine salvage |
| REAC:R-HSA-8956321 | 0.00214930898727 | 0.5 | DCK DGUOK | Nucleotide salvage |
| GO:0004138 | 0.0028092043205 | 0.5 | DCK DGUOK | deoxyguanosine kinase activity |
| KEGG:01232 | 0.00601982850302 | 0.5 | DCK DGUOK | Nucleotide metabolism |
| KEGG:00230 | 0.0118173906169 | 0.5 | DCK DGUOK | Purine metabolism |
| GO:0019136 | 0.0168521501606 | 0.5 | DCK DGUOK | deoxynucleoside kinase activity |
| REAC:R-HSA-15869 | 0.0297941212351 | 0.5 | DCK DGUOK | Metabolism of nucleotides |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| DCK | DGUOK | 0.999 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PLEKHG2 | DCK | 0.991 | 0.146 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ERC2 | DGUOK | 0.823 | 0.084 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ERC2 | DCK | 0.205 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes