hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14586.1

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
AMMECR1	Nuclear protein AMMECR1 (AMME syndrome candidate gene 1 protein)	5	UniProt NCBI
ARL4C	ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)	5	UniProt NCBI
BTBD7	BTB/POZ domain-containing protein 7	4	UniProt NCBI
CLP1	Polyribonucleotide 5'-hydroxyl-kinase Clp1 (EC 2.7.1.78) (Polyadenylation factor Clp1) (Polynucleotide kinase Clp1) (Pre-mRNA cleavage complex II protein Clp1)	5	UniProt NCBI
GADD45A	Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage-inducible transcript 1 protein) (DDIT-1)	5	UniProt NCBI
GREB1L	GREB1-like protein (Growth regulation by estrogen in breast cancer 1-like protein)	5	UniProt NCBI
PCF11	Pre-mRNA cleavage complex 2 protein Pcf11 (Pre-mRNA cleavage complex II protein Pcf11)	5	UniProt NCBI
PHLDA2	Pleckstrin homology-like domain family A member 2 (Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein) (Imprinted in placenta and liver protein) (Tumor-suppressing STF cDNA 3 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein) (p17-Beckwith-Wiedemann region 1 C) (p17-BWR1C)	5	UniProt NCBI
TSEN15	tRNA-splicing endonuclease subunit Sen15 (SEN15 homolog) (HsSEN15) (tRNA-intron endonuclease Sen15)	5	UniProt NCBI
TSEN2	tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2)	5	UniProt NCBI

Showing 1 to 10 of 13 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:5283	1.302095624e-14	0.384615384615	TSEN34 TSEN54 TSEN2 TSEN15 CLP1	tRNA splicing endonuclease
HP:0006850	5.87343548758e-09	0.307692307692	TSEN34 TSEN54 TSEN15 TSEN2	Hypoplasia of the ventral pons
HP:0012765	5.87343548758e-09	0.307692307692	TSEN34 TSEN54 TSEN15 TSEN2	Widened cerebellar subarachnoid space
HP:0200049	2.73823562594e-08	0.307692307692	TSEN34 TSEN54 TSEN15 TSEN2	Upper limb hypertonia
CORUM:5284	3.08880131998e-08	0.230769230769	TSEN54 CLP1 TSEN2	RNA endonuclease (SEN2deltaEx8, SEN54, CLP1)
HP:0003558	1.28897474085e-07	0.307692307692	TSEN34 TSEN54 TSEN15 TSEN2	Viral infection-induced rhabdomyolysis
HP:0031162	1.93250909762e-07	0.307692307692	TSEN34 TSEN54 TSEN15 TSEN2	Impaired oropharyngeal swallow response
REAC:R-HSA-6784531	2.15320027879e-07	0.384615384615	TSEN34 TSEN54 TSEN2 TSEN15 CLP1	tRNA processing in the nucleus
HP:0002268	9.2687804265e-07	0.307692307692	TSEN34 TSEN54 TSEN15 TSEN2	Paroxysmal dystonia
HP:0011171	2.3262323028e-06	0.307692307692	TSEN34 TSEN54 TSEN15 TSEN2	Simple febrile seizure

Showing 1 to 10 of 73 entries

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Protein 1	Protein 2	Score	ProteomeHD
TSEN15	TSEN34	1.0	0.22
TSEN15	TSEN2	0.999	0.084
CLP1	TSEN2	0.999	0.166
TSEN2	TSEN34	0.999	0.108
TSEN2	TSEN54	0.999	0.116
CLP1	TSEN54	0.999	0.124
TSEN15	CLP1	0.998	0.07
CLP1	TSEN34	0.998	0.12
CLP1	PCF11	0.997	0.27
TSEN15	TSEN54	0.994	0.098

Showing 1 to 10 of 56 entries

Related Complexes

Genename	Complexes
BTBD7	huMAP3_03873.1 huMAP3_06096.1 huMAP3_10939.1 huMAP3_11939.1 huMAP3_13639.1 huMAP3_14576.1 huMAP3_14586.1 huMAP3_15245.1
TSEN54	huMAP3_04582.1 huMAP3_06042.1 huMAP3_07243.1 huMAP3_10697.1 huMAP3_13483.1 huMAP3_13865.1 huMAP3_14586.1 huMAP3_14839.1
TSEN15	huMAP3_02940.1 huMAP3_06042.1 huMAP3_10697.1 huMAP3_13483.1 huMAP3_13865.1 huMAP3_14576.1 huMAP3_14586.1 huMAP3_14839.1 huMAP3_15245.1
PHLDA2	huMAP3_02940.1 huMAP3_04582.1 huMAP3_06042.1 huMAP3_10697.1 huMAP3_11956.1 huMAP3_13483.1 huMAP3_13693.1 huMAP3_14586.1 huMAP3_14839.1 huMAP3_14984.1
GREB1L	huMAP3_13483.1 huMAP3_14586.1 huMAP3_14839.1
AMMECR1	huMAP3_04582.1 huMAP3_08573.1 huMAP3_08812.1 huMAP3_10697.1 huMAP3_11762.1 huMAP3_13483.1 huMAP3_13511.1 huMAP3_14586.1 huMAP3_14839.1
CLP1	huMAP3_02940.1 huMAP3_04582.1 huMAP3_06042.1 huMAP3_10697.1 huMAP3_13483.1 huMAP3_14586.1 huMAP3_14839.1
PCF11	huMAP3_02940.1 huMAP3_04582.1 huMAP3_06042.1 huMAP3_10697.1 huMAP3_12111.1 huMAP3_13730.1 huMAP3_14483.1 huMAP3_14586.1
GADD45A	huMAP3_01737.1 huMAP3_01965.1 huMAP3_05425.1 huMAP3_07243.1 huMAP3_07720.1 huMAP3_07918.1 huMAP3_10622.1 huMAP3_12847.1 huMAP3_13865.1 huMAP3_14298.1 huMAP3_14586.1 huMAP3_14839.1
TSEN2	huMAP3_02940.1 huMAP3_04582.1 huMAP3_06042.1 huMAP3_10697.1 huMAP3_13483.1 huMAP3_13865.1 huMAP3_14586.1 huMAP3_14839.1
TSEN34	huMAP3_02940.1 huMAP3_04582.1 huMAP3_06042.1 huMAP3_10697.1 huMAP3_13483.1 huMAP3_13865.1 huMAP3_14586.1 huMAP3_14839.1
XRCC2	huMAP3_03417.1 huMAP3_07905.1 huMAP3_12173.1 huMAP3_12847.1 huMAP3_14586.1
ARL4C	huMAP3_01199.1 huMAP3_07243.1 huMAP3_13483.1 huMAP3_13865.1 huMAP3_14586.1 huMAP3_14839.1