hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_14589.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| POFUT1 | GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1) | 5 | UniProt NCBI |
| HEXB | Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A] | 5 | UniProt NCBI |
| NENF | Neudesin (Cell immortalization-related protein 2) (Neuron-derived neurotrophic factor) (Protein GIG47) (Secreted protein of unknown function) (SPUF protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6275 | 0.0249718442456 | 0.333333333333 | HEXB | HEXB homodimer complex |
| REAC:R-HSA-3656248 | 0.0498224659464 | 0.333333333333 | HEXB | Defective HEXB causes GM2G2 |
| CORUM:6274 | 0.0499402709677 | 0.333333333333 | HEXB | HEXA-HEXB complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HEXB | POFUT1 | 0.963 | 0.042 | bioplex_WMM Guru bioplex3_WMM fraction |
| NENF | POFUT1 | 0.951 | 0.19 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
| HEXB | NENF | 0.056 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| POFUT1 | huMAP3_08771.1 huMAP3_10763.1 huMAP3_14589.1 |
| HEXB | huMAP3_02312.1 huMAP3_08135.1 huMAP3_10763.1 huMAP3_13392.1 huMAP3_14235.1 huMAP3_14589.1 |
| NENF | huMAP3_04470.1 huMAP3_11747.1 huMAP3_13775.1 huMAP3_14589.1 |