hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14605.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CCNL1 | Cyclin-L1 (Cyclin-L) | 5 | UniProt NCBI |
| CPSF7 | Cleavage and polyadenylation specificity factor subunit 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Cleavage factor Im complex 59 kDa subunit) (CFIm59) (Pre-mRNA cleavage factor Im 59 kDa subunit) | 5 | UniProt NCBI |
| NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Cleavage factor Im complex 25 kDa subunit) (CFIm25) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Nudix hydrolase 21) (Pre-mRNA cleavage factor Im 68 kDa subunit) | 5 | UniProt NCBI |
| JPH3 | Junctophilin-3 (JP-3) (Junctophilin type 3) (Trinucleotide repeat-containing gene 22 protein) | 5 | UniProt NCBI |
| KHSRP | Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75) | 5 | UniProt NCBI |
| FUBP1 | Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1141 | 0.00133016076778 | 0.333333333333 | CPSF7 NUDT21 | CF IIAm complex (Cleavage factor IIAm complex) |
| REAC:R-HSA-77595 | 0.00440152140132 | 0.333333333333 | CPSF7 NUDT21 | Processing of Intronless Pre-mRNAs |
| REAC:R-HSA-75067 | 0.00902151290218 | 0.333333333333 | CPSF7 NUDT21 | Processing of Capped Intronless Pre-mRNA |
| GO:1990120 | 0.0210651876021 | 0.333333333333 | CPSF7 NUDT21 | messenger ribonucleoprotein complex assembly |
| KEGG:03015 | 0.029291198851 | 0.333333333333 | CPSF7 NUDT21 | mRNA surveillance pathway |
| REAC:R-HSA-72187 | 0.0379731829042 | 0.333333333333 | CPSF7 NUDT21 | mRNA 3'-end processing |
| GO:0110104 | 0.042122686785 | 0.333333333333 | CPSF7 NUDT21 | mRNA alternative polyadenylation |
| HPA:0010013 | 0.0436548629982 | 0.5 | KHSRP CPSF7 FUBP1 | adipose tissue; adipocytes[High] |
| REAC:R-HSA-73856 | 0.0498675109087 | 0.333333333333 | CPSF7 NUDT21 | RNA Polymerase II Transcription Termination |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CPSF7 | NUDT21 | 0.992 | 0.706 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction boldt_WMM treiber_WMM |
| FUBP1 | KHSRP | 0.986 | 0.732 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| NUDT21 | KHSRP | 0.974 | 0.786 | hein_WMM bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| CPSF7 | CCNL1 | 0.957 | 0.136 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NUDT21 | JPH3 | 0.901 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| NUDT21 | FUBP1 | 0.81 | 0.488 | bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| NUDT21 | CCNL1 | 0.786 | 0.178 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| CPSF7 | FUBP1 | 0.204 | 0.422 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM treiber_WMM |
| JPH3 | KHSRP | 0.123 | bioplex3_HEK293 WMM_only | |
| JPH3 | FUBP1 | 0.054 | bioplex3_HEK293 WMM_only | |
| CPSF7 | JPH3 | 0.037 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CPSF7 | KHSRP | 0.012 | 0.39 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| FUBP1 | CCNL1 | 0.009 | 0.312 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| KHSRP | CCNL1 | 0.001 | 0.252 | bioplex3_HEK293 youn_WMM bioplex3_HCT116 WMM_only |
Related Complexes