hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14608.1

Confidence: Medium

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Genename	Protein Name	Uniprot Annotation Score	Links
CDC34	Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)	5	UniProt NCBI
CTC1	CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B)	5	UniProt NCBI
STN1	CST complex subunit STN1 (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog)	5	UniProt NCBI
TEN1	CST complex subunit TEN1 (Protein telomeric pathways with STN1 homolog) (Telomere length regulation protein TEN1 homolog)	5	UniProt NCBI
UBE2R2	Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2)	5	UniProt NCBI
VWC2L	von Willebrand factor C domain-containing protein 2-like (VWC2-like protein) (Brorin-like)	5	UniProt NCBI

Showing 1 to 6 of 6 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6075	4.67737426163e-09	0.5	CTC1 STN1 TEN1	CST complex
GO:1990879	1.92240082153e-06	0.5	CTC1 STN1 TEN1	CST complex
REAC:R-HSA-174430	2.01823692347e-06	0.5	CTC1 STN1 TEN1	Telomere C-strand synthesis initiation
REAC:R-HSA-174411	1.83108883385e-05	0.5	CTC1 STN1 TEN1	Polymerase switching on the C-strand of the telomere
REAC:R-HSA-174417	4.20912658431e-05	0.5	CTC1 STN1 TEN1	Telomere C-strand (Lagging Strand) Synthesis
REAC:R-HSA-180786	0.000146098747122	0.5	CTC1 STN1 TEN1	Extension of Telomeres
GO:0000782	0.00042234232358	0.5	CTC1 STN1 TEN1	telomere cap complex
GO:0000783	0.00042234232358	0.5	CTC1 STN1 TEN1	nuclear telomere cap complex
GO:0140445	0.000548960443183	0.5	CTC1 STN1 TEN1	chromosome, telomeric repeat region
REAC:R-HSA-157579	0.00112585873244	0.5	CTC1 STN1 TEN1	Telomere Maintenance

Showing 1 to 10 of 20 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
UBE2R2	CDC34	0.999	0.186	bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
STN1	TEN1	0.998		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
STN1	CTC1	0.998	0.082	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
TEN1	CTC1	0.993		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116
CDC34	CTC1	0.976	0.058	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
STN1	CDC34	0.945	0.146	bioplex3_WMM bioplex3_HCT116 WMM_only
STN1	VWC2L	0.917		bioplex3_HEK293 bioplex3_WMM WMM_only
VWC2L	CTC1	0.895		bioplex3_HEK293 bioplex3_WMM WMM_only
UBE2R2	CTC1	0.76	0.084	bioplex3_HEK293 bioplex3_WMM WMM_only
STN1	UBE2R2	0.691	0.0848888888889	bioplex3_HEK293 bioplex3_WMM WMM_only

Showing 1 to 10 of 10 entries

Related Complexes

Genename	Complexes
STN1	huMAP3_01570.1 huMAP3_05430.1 huMAP3_09250.1 huMAP3_14608.1
VWC2L	huMAP3_03590.1 huMAP3_04209.1 huMAP3_09172.1 huMAP3_10918.1 huMAP3_11260.1 huMAP3_11373.1 huMAP3_11687.1 huMAP3_12920.1 huMAP3_14430.1 huMAP3_14608.1 huMAP3_14931.1
CTC1	huMAP3_05430.1 huMAP3_05946.1 huMAP3_08768.1 huMAP3_09250.1 huMAP3_14608.1
TEN1	huMAP3_01570.1 huMAP3_02475.1 huMAP3_05946.1 huMAP3_09250.1 huMAP3_12858.1 huMAP3_14608.1
UBE2R2	huMAP3_03088.1 huMAP3_03868.1 huMAP3_04044.1 huMAP3_05733.1 huMAP3_06177.1 huMAP3_07002.1 huMAP3_07489.1 huMAP3_07691.1 huMAP3_10453.1 huMAP3_10829.1 huMAP3_12112.1 huMAP3_12772.1 huMAP3_14608.1
CDC34	huMAP3_03088.1 huMAP3_03868.1 huMAP3_04044.1 huMAP3_06177.1 huMAP3_07002.1 huMAP3_07691.1 huMAP3_10453.1 huMAP3_10829.1 huMAP3_12112.1 huMAP3_12772.1 huMAP3_14608.1