hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14611.1
Complex Portal: CPX-21733
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OR6Q1 | Olfactory receptor 6Q1 (Olfactory receptor OR11-226) | 3 | UniProt NCBI |
| OXT | Oxytocin-neurophysin 1 (OT-NPI) [Cleaved into: Oxytocin (Ocytocin); Neurophysin 1] | 5 | UniProt NCBI |
| GAREM2 | GRB2-associated and regulator of MAPK protein 2 (GRB2-associated and regulator of MAPK1-like) | 3 | UniProt NCBI |
| SHC1 | SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1) | 5 | UniProt NCBI |
| ALK | ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246) | 5 | UniProt NCBI |
| GAREM1 | GRB2-associated and regulator of MAPK protein 1 (GRB2-associated and regulator of MAPK1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4928 | 0.000534376000489 | 0.4 | GAREM2 ALK | MAPK pathway in congenital thyroid cancer |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GAREM2 | GAREM1 | 0.998 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GAREM1 | OR6Q1 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SHC1 | GAREM1 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| OXT | SHC1 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| GAREM2 | OR6Q1 | 0.902 | bioplex3_WMM WMM_only | ||
| SHC1 | OR6Q1 | 0.892 | bioplex3_WMM WMM_only | ||
| SHC1 | ALK | 0.827 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SHC1 | GAREM2 | 0.796 | bioplex3_WMM WMM_only |
Related Complexes