hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_14621.1

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
ELF2	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor)	5	UniProt NCBI
ADAM22	Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22) (Metalloproteinase-disintegrin ADAM22-3) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2)	5	UniProt NCBI
LGI1	Leucine-rich glioma-inactivated protein 1 (Epitempin-1)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:7395	3.41752350426e-06	0.666666666667	LGI1 ADAM22	ADAM22-LGI1 complex
REAC:R-HSA-5682910	0.000306718584473	0.666666666667	LGI1 ADAM22	LGI-ADAM interactions
HP:0002266	0.00708857159683	0.666666666667	LGI1 ADAM22	Focal clonic seizure
HP:0007334	0.00985306624309	0.666666666667	LGI1 ADAM22	Bilateral tonic-clonic seizure with focal onset
HP:0020221	0.0262448238426	0.666666666667	LGI1 ADAM22	Clonic seizure

Protein 1	Protein 2	Score	ProteomeHD	Evidence
ADAM22	LGI1	0.984		bioplex3_HEK293 bioplex3_WMM WMM_only
ELF2	LGI1	0.901		bioplex3_HEK293 bioplex3_WMM WMM_only
ELF2	ADAM22	0.085		bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
ELF2	huMAP3_00710.1 huMAP3_01324.1 huMAP3_06065.1 huMAP3_06983.1 huMAP3_07161.1 huMAP3_08341.1 huMAP3_08472.1 huMAP3_08475.1 huMAP3_08908.1 huMAP3_09086.1 huMAP3_10941.1 huMAP3_11883.1 huMAP3_12494.1 huMAP3_12561.1 huMAP3_13128.1 huMAP3_14146.1 huMAP3_14621.1
ADAM22	huMAP3_04951.1 huMAP3_10589.1 huMAP3_10708.1 huMAP3_11788.1 huMAP3_13027.1 huMAP3_13284.1 huMAP3_14621.1
LGI1	huMAP3_04951.1 huMAP3_10589.1 huMAP3_10790.1 huMAP3_11788.1 huMAP3_12494.1 huMAP3_13389.1 huMAP3_14014.1 huMAP3_14621.1