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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_14633.1
Complex Portal:
CPX-21828
Confidence:
Medium
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
BMP4
Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)
5
UniProt
NCBI
IL20
Interleukin-20 (IL-20) (Cytokine Zcyto10)
5
UniProt
NCBI
LEP
Leptin (Obese protein) (Obesity factor)
5
UniProt
NCBI
LEPR
Leptin receptor (LEP-R) (HuB219) (OB receptor) (OB-R) (CD antigen CD295)
5
UniProt
NCBI
TWSG1
Twisted gastrulation protein homolog 1
5
UniProt
NCBI
Showing 1 to 5 of 5 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
WP:WP5400
9.18788843787e-05
0.5
LEPR LEP
6q16 copy number variation
WP:WP3934
0.000114838123418
0.5
LEPR LEP
Leptin and adiponectin
KEGG:04630
0.000124866609719
0.75
LEPR IL20 LEP
JAK-STAT signaling pathway
WP:WP3935
0.000306067313039
0.5
LEPR LEP
Leptin insulin signaling overlap
KEGG:04060
0.000426496412782
0.75
LEPR IL20 LEP
Cytokine-cytokine receptor interaction
HP:0005419
0.000501460556964
0.5
LEPR LEP
Decreased T cell activation
HP:0410035
0.000501460556964
0.5
LEPR LEP
Abnormal T cell activation
HP:0003292
0.00183784982408
0.5
LEPR LEP
Decreased serum leptin
HP:0004361
0.00260592941411
0.5
LEPR LEP
Abnormal circulating leptin concentration
HP:0004926
0.00303997345979
0.5
LEPR LEP
Orthostatic hypotension due to autonomic dysfunction
Showing 1 to 10 of 37 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
LEPR
LEP
0.997
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
TWSG1
BMP4
0.979
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
BMP4
IL20
0.932
bioplex3_WMM bioplex3_HCT116 WMM_only
BMP4
LEP
0.86
bioplex3_WMM bioplex3_HCT116 WMM_only
BMP4
LEPR
0.175
bioplex3_WMM WMM_only
Showing 1 to 5 of 5 entries
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Related Complexes
Genename
Complexes
LEPR
huMAP3_00554.1
huMAP3_06280.1
huMAP3_08004.1
huMAP3_14276.1
huMAP3_14616.1
huMAP3_14633.1
BMP4
huMAP3_00379.1
huMAP3_04460.1
huMAP3_06092.1
huMAP3_09977.1
huMAP3_11438.1
huMAP3_12416.1
huMAP3_12892.1
huMAP3_14633.1
LEP
huMAP3_01484.1
huMAP3_06280.1
huMAP3_08004.1
huMAP3_14276.1
huMAP3_14633.1
IL20
huMAP3_00634.1
huMAP3_05862.1
huMAP3_11438.1
huMAP3_12416.1
huMAP3_13232.1
huMAP3_14633.1
huMAP3_15084.1
TWSG1
huMAP3_00379.1
huMAP3_11438.1
huMAP3_14633.1