hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_14637.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RELL1 | RELT-like protein 1 | 5 | UniProt NCBI |
| RELL2 | RELT-like protein 2 | 5 | UniProt NCBI |
| OXSR1 | Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) | 5 | UniProt NCBI |
| MGST2 | Microsomal glutathione S-transferase 2 (Microsomal GST-2) (EC 2.5.1.18) (Glutathione peroxidase MGST2) (EC 1.11.1.-) (Leukotriene C4 synthase MGST2) (EC 4.4.1.20) (Microsomal glutathione S-transferase II) (Microsomal GST-II) | 5 | UniProt NCBI |
| STK39 | STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1900745 | 0.000929874009882 | 0.6 | RELL1 RELL2 STK39 | positive regulation of p38MAPK cascade |
| GO:1900744 | 0.00350285844735 | 0.6 | RELL1 RELL2 STK39 | regulation of p38MAPK cascade |
| GO:0038066 | 0.00744248347584 | 0.6 | RELL1 RELL2 STK39 | p38MAPK cascade |
| GO:0003096 | 0.0468008499735 | 0.4 | OXSR1 STK39 | renal sodium ion transport |
| GO:0038146 | 0.0468008499735 | 0.4 | OXSR1 STK39 | chemokine (C-X-C motif) ligand 12 signaling pathway |
| GO:0070294 | 0.0468008499735 | 0.4 | OXSR1 STK39 | renal sodium ion absorption |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| OXSR1 | RELL2 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| STK39 | RELL2 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RELL1 | OXSR1 | 0.992 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| MGST2 | RELL2 | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| STK39 | OXSR1 | 0.979 | 0.198 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| RELL1 | STK39 | 0.966 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| STK39 | MGST2 | 0.189 | 0.018 | bioplex_WMM bioplex3_WMM WMM_only |
| OXSR1 | MGST2 | 0.178 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes